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Yizhou Zhang Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, Hebei, China
Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, Hebei, China

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Meiqin Chen Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China

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Huan Chen Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, Hebei, China
Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, Hebei, China

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Shixiong Mi Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China

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Chang Wang Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, Hebei, China
Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, Hebei, China

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Hongchun Zuo Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China

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Leigang Song Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China

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Juan Du Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, Hebei, China
Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, Hebei, China

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Huixian Cui Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, Hebei, China
Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, Hebei, China

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Sha Li Department of Human Anatomy, Hebei Medical University, Shijiazhuang, Hebei, China
Neuroscience Research Center, Hebei Medical University, Shijiazhuang, Hebei, China
Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, Hebei, China

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Erk1/2 inhibitor blocked the structural synaptic plasticity of testosterone on primary rat hippocampal neurons. Phospho-CREB may bind to the promoters of susceptibility genes associated with synaptic plasticity to enhance their transcription and then

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Karin L Gustafsson Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Sofia Movérare-Skrtic Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Helen H Farman Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Cecilia Engdahl Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Petra Henning Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Karin H Nilsson Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Julia M Scheffler Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Edina Sehic Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Ulrika Islander Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Ellis Levin Division of Endocrinology, Department of Medicine, University of California, Irvine, Irvine, California, USA
Department of Veterans Affairs Medical Center, Long Beach, Long Beach, California, USA

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Claes Ohlsson Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Department of Drug Treatment, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden

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Marie K Lagerquist Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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matrix metalloproteinase 2 activity in the rat uterus . Biology of Reproduction 72 830 – 841 . ( https://doi.org/10.1095/biolreprod.104.034595 ) 15576828 Hewitt SC Deroo BJ Hansen K Collins J Grissom S Afshari CA Korach KS 2003 Estrogen

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Antonio Gázquez Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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Francisca Rodríguez Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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María Sánchez-Campillo Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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Lidia E Martínez-Gascón Department of Clinical Analysis, Biomedical Research Institute of Murcia, Santa Lucia General University Hospital, Murcia, Spain

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Marino B Arnao Department of Plant Biology (Plant Physiology), University of Murcia, Murcia, Spain

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Pedro Saura-Garre Department of Clinical Psychology, University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain

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María D Albaladejo-Otón Department of Clinical Analysis, Biomedical Research Institute of Murcia, Santa Lucia General University Hospital, Murcia, Spain

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Elvira Larqué Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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and later on visual and cognitive development ( Innis 2007 ). The aim of the present study was to investigate the effects of AdipoRon administration during gestation on glycaemia and lipid profile in both mothers and adult offspring using a rat model

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E J Agnew Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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A Garcia-Burgos Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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R V Richardson Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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H Manos Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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A J W Thomson Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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K Sooy Mass Spectrometry Core, Edinburgh Clinical Research Facility, Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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G Just Mass Spectrometry Core, Edinburgh Clinical Research Facility, Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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N Z M Homer Mass Spectrometry Core, Edinburgh Clinical Research Facility, Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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C M Moran Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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P J Brunton Centre for Discovery Brain Sciences, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, UK

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G A Gray Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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K E Chapman Centre for Cardiovascular Science, The University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK

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concentration ~10-fold lower than in the maternal liver. This is consistent with previous reports of a gradient of this magnitude between maternal and fetal serum in the late gestation rat ( Varma 1986 ). Interestingly, levels of 6-hydroxydexamethasone, an

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K A Staines
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A S Pollard
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I M McGonnell
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C Farquharson Comparative Biomedical Sciences, Roslin Institute and R(D)SVS, The Royal Veterinary College, Royal College Street, London NW1 0TU, UK

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A A Pitsillides
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.1016/j.joca.2003.09.016 ) Bush PG Parisinos CA Hall AC 2008 The osmotic sensitivity of rat growth plate chondrocytes in situ ; clarifying the mechanisms of hypertrophy . Journal of Cellular Physiology 214 621 – 629 . ( doi:10.1002/jcp

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J Jeyabalan
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M Shah
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B Viollet Department of Veterinary Basic Sciences, INSERM, CNRS, Université Paris Decartes, INSERM, Department of Endocrinology, Royal Veterinary College, Royal College Street, London NW1 0TU, UK
Department of Veterinary Basic Sciences, INSERM, CNRS, Université Paris Decartes, INSERM, Department of Endocrinology, Royal Veterinary College, Royal College Street, London NW1 0TU, UK
Department of Veterinary Basic Sciences, INSERM, CNRS, Université Paris Decartes, INSERM, Department of Endocrinology, Royal Veterinary College, Royal College Street, London NW1 0TU, UK

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J P Roux Department of Veterinary Basic Sciences, INSERM, CNRS, Université Paris Decartes, INSERM, Department of Endocrinology, Royal Veterinary College, Royal College Street, London NW1 0TU, UK

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P Chavassieux Department of Veterinary Basic Sciences, INSERM, CNRS, Université Paris Decartes, INSERM, Department of Endocrinology, Royal Veterinary College, Royal College Street, London NW1 0TU, UK

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M Korbonits Department of Veterinary Basic Sciences, INSERM, CNRS, Université Paris Decartes, INSERM, Department of Endocrinology, Royal Veterinary College, Royal College Street, London NW1 0TU, UK

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C Chenu
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rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase . Journal of Biological Chemistry 271 27879 – 27887 . doi:10.1074/jbc.271.44.27879 . Hawley SA Boudeau J Reid JL Mustard

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Graham W Aberdeen Departments of Obstetrics, Gynecology, Reproductive Sciences and Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA

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Jeffery S Babischkin Departments of Obstetrics, Gynecology, Reproductive Sciences and Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA

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Gerald J Pepe Department of Physiological Sciences, Eastern Virginia Medical School, Norfolk, Virginia, USA

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Eugene D Albrecht Departments of Obstetrics, Gynecology, Reproductive Sciences and Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA

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Mediation by M 3 -muscarinic receptors of both endothelium-dependent contraction and relaxation to acetylcholine in the aorta of the spontaneously hypertensive rat . British Journal of Pharmacology 112 519 – 524 . ( https://doi.org/10.1111/j.1476

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Renata Risi Department of Experimental Medicine, Sapienza University of Rome, Sapienza University of Rome, Rome, Italy
University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK

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Antonio Vidal-Puig University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK
Cambridge University Nanjing Centre of Technology and Innovation, Nanjing, P. R. China
Centro de Investigacion Principe Felipe, Valencia, Spain

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Guillaume Bidault University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK

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to their chain length and degree of saturation. It has been shown that saturated FAs (SFAs), such as palmitic (C16:0) and stearate (C18:0), are better enhancers of GSIS than mono- and polyunsaturated FAs in the perfused rat pancreas ( Stein et al

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Tingting Yang Department of Physiology and Biophysics, School of Life Sciences, Institutes of Brain Science, Fudan University, Shanghai, China

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Min He Department of Physiology and Biophysics, School of Life Sciences, Institutes of Brain Science, Fudan University, Shanghai, China

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Hailiang Zhang Department of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Paula Q Barrett Department of Pharmacology, University of Virginia, Charlottesville, Virginia, USA

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Changlong Hu Department of Physiology and Biophysics, School of Life Sciences, Institutes of Brain Science, Fudan University, Shanghai, China

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secretagogues in vivo ( Barrett et al . 2016 , Yang et al . 2018 ). ZG voltage-gated calcium channels are differentially expressed among mammalian species. Mainly two types of calcium currents have been identified in human, rat, mouse, and bovine ZG cells

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A Tsuchiya Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan

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T Kanno Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan

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T Nishizaki Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan

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primary rat adipocytes ( Bae et al . 2003 , Gonzalez & McGraw 2009 ). Isoform-specific activation, therefore, does not account for the selective requirement for Akt2 in the control of GLUT4 translocation to the plasma membrane in adipocytes. Akt2, but

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