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regulated by gene regulation networks and epigenetic control, are also of great importance. Consequently, study of variations in levels of RNA transcripts has also been applied to identify new molecular mechanisms and signalling pathways involved in
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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activity) and that results in a male and female differential endocrine susceptibility and gene regulation, particularly in sex steroid-responsive genes. The relevance of oestrogen programming mechanisms within the mammalian foetus and perinatal time period
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organization and gene regulation . European Journal of Biochemistry 157 27 – 31 . ( doi:10.1111/j.1432-1033.1986.tb09633.x ) Hayashi H Oohashi M 1995 Incorporation of acetyl-CoA generated from peroxisomal β-oxidation into ethanolamine plasmalogen
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gene (data not shown). This suggested that oestrogens may contribute to RBP4 gene regulation. To determine whether 17β-estradiol regulates Rbp4 expression in adipocytes, we treated differentiated 3T3L1 adipocytes with increasing concentrations (0, 1
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fetal adrenal gland: potential interactions in gene regulation . Molecular Endocrinology 15 57 – 68 doi:10.1210/me.15.1.57 . Hay CW Docherty K 2006 Comparative analysis of insulin gene promoters: implications for diabetes research
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2002 Apelin-immunoreactivity in the rat hypothalamus and pituitary . Neuroscience Letters 327 193 – 197 . Burbach JPH Luckman SM Murphy D Gainer H 2001 Gene-regulation in the magnocellular hypothalamo-neurohypophsial system
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Sauvageau M Goff L Rinn JL Pachter L 2013 Differential analysis of gene regulation at transcript resolution with RNA-seq . Nature Biotechnology 31 46 – 53 . ( https://doi.org/10.1038/nbt.2450 ) 10.1038/nbt.2450 23222703 Vinogradov
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of mouse skin tumor promotion by adrenalectomy . Carcinogenesis 13 1925 – 1928 . ( https://doi.org/10.1093/carcin/13.10.1925 ) Pecci A Ogara MF Sanz RT & Vicent GP 2022 Choosing the right partner in hormone-dependent gene regulation