Search Results

You are looking at 11 - 20 of 31 items for :

  • adiponectin x
  • Refine by access: Open Access content only x
Clear All
Gencer Sancar German Center for Diabetes Research, Neuherberg, Germany
Department of Internal Medicine IV, Division of Diabetology, Endocrinology and Nephrology, Eberhard-Karls University of Tübingen, Tübingen, Germany
Institute for Diabetes Research and Metabolic Diseases, Helmholtz Center Munich, Eberhard-Karls University of Tübingen, Tübingen, Germany

Search for other papers by Gencer Sancar in
Google Scholar
PubMed
Close
and
Andreas L Birkenfeld German Center for Diabetes Research, Neuherberg, Germany
Department of Internal Medicine IV, Division of Diabetology, Endocrinology and Nephrology, Eberhard-Karls University of Tübingen, Tübingen, Germany
Institute for Diabetes Research and Metabolic Diseases, Helmholtz Center Munich, Eberhard-Karls University of Tübingen, Tübingen, Germany

Search for other papers by Andreas L Birkenfeld in
Google Scholar
PubMed
Close

anti-inflammatory factors such as adiponectin and IL-10, exacerbating hepatic inflammation, insulin resistance, and steatosis ( Abenavoli & Peta 2014 , Stojsavljević et al. 2014 ). While adipose tissue is an endocrine organ and the main storage place

Open access
T Mracek
Search for other papers by T Mracek in
Google Scholar
PubMed
Close
,
D Gao
Search for other papers by D Gao in
Google Scholar
PubMed
Close
,
T Tzanavari
Search for other papers by T Tzanavari in
Google Scholar
PubMed
Close
,
Y Bao
Search for other papers by Y Bao in
Google Scholar
PubMed
Close
,
X Xiao
Search for other papers by X Xiao in
Google Scholar
PubMed
Close
,
C Stocker Obesity Biology Research Unit, Clore Laboratory, School of Clinical Sciences, University of Liverpool, Duncan Building, Liverpool L69 3GA, UK

Search for other papers by C Stocker in
Google Scholar
PubMed
Close
,
P Trayhurn
Search for other papers by P Trayhurn in
Google Scholar
PubMed
Close
, and
C Bing
Search for other papers by C Bing in
Google Scholar
PubMed
Close

suggests that altered production of adipose-derived protein factors (adipokines), such as leptin, tumour necrosis factor-α (TNFα), adiponectin and chemerin, plays an important role. Zinc-α2-glycoprotein (ZAG, also called AZGP1) is a secreted, soluble

Open access
Renata Risi Department of Experimental Medicine, Sapienza University of Rome, Sapienza University of Rome, Rome, Italy
University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK

Search for other papers by Renata Risi in
Google Scholar
PubMed
Close
,
Antonio Vidal-Puig University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK
Cambridge University Nanjing Centre of Technology and Innovation, Nanjing, P. R. China
Centro de Investigacion Principe Felipe, Valencia, Spain

Search for other papers by Antonio Vidal-Puig in
Google Scholar
PubMed
Close
, and
Guillaume Bidault University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK

Search for other papers by Guillaume Bidault in
Google Scholar
PubMed
Close

higher release of adiponectin ( Drolet et al. 2009 ) and leptin ( Van Harmelen et al. 1998 ). On the other hand, vWAT tends to release larger amounts of pro-inflammatory cytokines, such as IL-6 ( Fontana et al. 2007 ). Concerning obesity, an

Open access
Yanli Miao Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Search for other papers by Yanli Miao in
Google Scholar
PubMed
Close
,
Haojie Qin Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Search for other papers by Haojie Qin in
Google Scholar
PubMed
Close
,
Yi Zhong Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Search for other papers by Yi Zhong in
Google Scholar
PubMed
Close
,
Kai Huang Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Search for other papers by Kai Huang in
Google Scholar
PubMed
Close
, and
Caijun Rao Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Search for other papers by Caijun Rao in
Google Scholar
PubMed
Close

organ that secretes a variety of 'adipokines' including leptin, adiponectin, resistin, and asprosin ( Fasshauer & Bluher 2015 ). Asprosin, the c-terminal propeptide of FBN1 ( Muthu & Reinhardt 2020 ), is a novel adipokine secreted mainly by white adipose

Open access
Geoffrey L Hammond Departments of Cellular & Physiological Sciences and Obstetrics & Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada

Search for other papers by Geoffrey L Hammond in
Google Scholar
PubMed
Close

-inflammatory cytokines (TNF-α and IL-1β) in obese individuals contribute to a reduced hepatic expression of SHBG and low plasma SHBG levels by reducing HNF4-α levels in the liver ( Simo et al. 2012a , b ). Furthermore, adiponectin appears to increase plasma SHBG

Open access
Xuefeng Yang Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Xuefeng Yang in
Google Scholar
PubMed
Close
,
Shuang Mei Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Shuang Mei in
Google Scholar
PubMed
Close
,
Haihua Gu Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Haihua Gu in
Google Scholar
PubMed
Close
,
Huailan Guo Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Huailan Guo in
Google Scholar
PubMed
Close
,
Longying Zha Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Longying Zha in
Google Scholar
PubMed
Close
,
Junwei Cai Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Junwei Cai in
Google Scholar
PubMed
Close
,
Xuefeng Li Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Xuefeng Li in
Google Scholar
PubMed
Close
,
Zhenqi Liu Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Zhenqi Liu in
Google Scholar
PubMed
Close
, and
Wenhong Cao Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA

Search for other papers by Wenhong Cao in
Google Scholar
PubMed
Close

). Leptin, adiponectin, and tumor necrosis factor α (TNFα) were measured with kits obtained from Abcam (Cambridge, UK) (Cat No: ab100718, ab108785, and ab46105). Endogenous insulin and growth hormone were detected with ELISA kits purchased from Millipore

Open access
Ya-Li Yang Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Ya-Li Yang in
Google Scholar
PubMed
Close
,
Li-Rong Ren Shenzhen Key Laboratory of Birth Defects, Shenzhen Baoan Maternal and Child Health Hospital, Shenzhen, Guangdong, China

Search for other papers by Li-Rong Ren in
Google Scholar
PubMed
Close
,
Li-Feng Sun Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Li-Feng Sun in
Google Scholar
PubMed
Close
,
Chen Huang Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
University of Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Chen Huang in
Google Scholar
PubMed
Close
,
Tian-Xia Xiao Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Tian-Xia Xiao in
Google Scholar
PubMed
Close
,
Bao-Bei Wang Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Bao-Bei Wang in
Google Scholar
PubMed
Close
,
Jie Chen Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Jie Chen in
Google Scholar
PubMed
Close
,
Brian A Zabel Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, California, USA, and Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA

Search for other papers by Brian A Zabel in
Google Scholar
PubMed
Close
,
Peigen Ren Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Peigen Ren in
Google Scholar
PubMed
Close
, and
Jian V Zhang Research Laboratory for Reproductive Health, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Search for other papers by Jian V Zhang in
Google Scholar
PubMed
Close

testicular tissue in vitro , leptin inhibited the ground state, and human chorionic gonadotropin (hCG)-stimulated testosterone secretion. Caminos et al . (2008) found that after adiponectin treatment, the ground state and hCG-stimulated testosterone

Open access
Thomas Nicholson Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK

Search for other papers by Thomas Nicholson in
Google Scholar
PubMed
Close
,
Chris Church MedImmune, Cardiovascular and Metabolic Disease (CVMD), Milstein Building, Cambridge, UK

Search for other papers by Chris Church in
Google Scholar
PubMed
Close
,
Kostas Tsintzas MRC-ARUK Centre for Musculoskeletal Ageing Research, School of Life Sciences, Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham, UK

Search for other papers by Kostas Tsintzas in
Google Scholar
PubMed
Close
,
Robert Jones MRC-ARUK Centre for Musculoskeletal Ageing Research, School of Life Sciences, Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham, UK

Search for other papers by Robert Jones in
Google Scholar
PubMed
Close
,
Leigh Breen Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK

Search for other papers by Leigh Breen in
Google Scholar
PubMed
Close
,
Edward T Davis The Royal Orthopaedic Hospital NHS Foundation Trust, Northfield, Birmingham, UK

Search for other papers by Edward T Davis in
Google Scholar
PubMed
Close
,
David J Baker MedImmune, Cardiovascular and Metabolic Disease (CVMD), Milstein Building, Cambridge, UK

Search for other papers by David J Baker in
Google Scholar
PubMed
Close
, and
Simon W Jones Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK

Search for other papers by Simon W Jones in
Google Scholar
PubMed
Close

important contributors to tissue crosstalk and systemic inflammatory burden. The functional role of the adipokines, leptin and adiponectin, as mediators of metabolic health and insulin sensitivity are well described. However, at present the functional role

Open access
Kevin J P Ryan Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Loughborough, Leics LE12 5RD, UK

Search for other papers by Kevin J P Ryan in
Google Scholar
PubMed
Close
,
Zoe C T R Daniel Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Loughborough, Leics LE12 5RD, UK

Search for other papers by Zoe C T R Daniel in
Google Scholar
PubMed
Close
,
Lucinda J L Craggs Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Loughborough, Leics LE12 5RD, UK

Search for other papers by Lucinda J L Craggs in
Google Scholar
PubMed
Close
,
Tim Parr Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Loughborough, Leics LE12 5RD, UK

Search for other papers by Tim Parr in
Google Scholar
PubMed
Close
, and
John M Brameld Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Loughborough, Leics LE12 5RD, UK

Search for other papers by John M Brameld in
Google Scholar
PubMed
Close

all three adipose-specific marker genes, PPAR γ 2 ( PPARG ; Fig. 3 A), fatty acid binding protein 4 ( FABP4 ; Fig. 3 B) and adiponectin/ ADIPOQ ( Fig. 3 C), were induced in a 1,25(OH) 2 D 3 concentration and time-dependent manner ( P <0.001 for

Open access
Alyce M Martin College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia

Search for other papers by Alyce M Martin in
Google Scholar
PubMed
Close
,
Emily W Sun College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia

Search for other papers by Emily W Sun in
Google Scholar
PubMed
Close
, and
Damien J Keating College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia
Nutrition and Metabolism, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia

Search for other papers by Damien J Keating in
Google Scholar
PubMed
Close

of these adipokines, which poses another secondary mechanism by which they regulate peripheral metabolism via adipose tissue. Specifically, 5-HT attenuates the release of adiponectin from WAT ( Uchida-Kitajima et al . 2008 ), an insulin

Open access