Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 11 - 20 of 127 items for :

  • Refine by access: Open Access content only x
Clear All
Christina Antza Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

Search for other papers by Christina Antza in
Google Scholar
PubMed Close
,
Georgios Kostopoulos Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece

Search for other papers by Georgios Kostopoulos in
Google Scholar
PubMed Close
,
Samiul Mostafa Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

Search for other papers by Samiul Mostafa in
Google Scholar
PubMed Close
,
Krishnarajah Nirantharakumar Institute of Applied Health Research, University of Birmingham, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

Search for other papers by Krishnarajah Nirantharakumar in
Google Scholar
PubMed Close
, and
Abd Tahrani Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

Search for other papers by Abd Tahrani in
Google Scholar
PubMed Close

) ( https://apps.who.int/gho/data/view.main.REGION2480A?lang=en Accessed (September) (2021)). Considering the health and economic consequences associated with obesity (type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), cancer, mortality), there

Article Type:
Review Article
Collections:
Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-21-0155
Volume/Issue:
Volume 252: Issue 2
Open access
Bernadette M Trojanowski Institute of Physiological Chemistry, Ulm University, Ulm, Germany

Search for other papers by Bernadette M Trojanowski in
Google Scholar
PubMed Close
,
Heba H Salem Faculty of Pharmacy, Cairo University, Cairo, Egypt
Faculty of Pharmacy, King Khalid University, Abha, Saudi Arabia

Search for other papers by Heba H Salem in
Google Scholar
PubMed Close
,
Heike Neubauer Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany

Search for other papers by Heike Neubauer in
Google Scholar
PubMed Close
,
Eric Simon Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany

Search for other papers by Eric Simon in
Google Scholar
PubMed Close
,
Martin Wagner Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, Ulm University, Ulm, Germany

Search for other papers by Martin Wagner in
Google Scholar
PubMed Close
,
Rajkumar Dorajoo Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore

Search for other papers by Rajkumar Dorajoo in
Google Scholar
PubMed Close
,
Bernhard O Boehm Lee Kong Chiang School of Medicine, Nanyang Technological University, Singapore, Singapore
Imperial College London, London, UK

Search for other papers by Bernhard O Boehm in
Google Scholar
PubMed Close
,
Leticia Labriola Institute of Physiological Chemistry, Ulm University, Ulm, Germany
Department of Biochemistry, University of São Paulo, São Paulo, Brazil

Search for other papers by Leticia Labriola in
Google Scholar
PubMed Close
,
Thomas Wirth Institute of Physiological Chemistry, Ulm University, Ulm, Germany

Search for other papers by Thomas Wirth in
Google Scholar
PubMed Close
, and
Bernd Baumann Institute of Physiological Chemistry, Ulm University, Ulm, Germany

Search for other papers by Bernd Baumann in
Google Scholar
PubMed Close

Introduction Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous form of diabetes that is inherited in an autosomal-dominant pattern and in general, affected families have a history of diabetes over several generations

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0208
Volume/Issue:
Volume 244: Issue 2
Open access
T’ng Choong Kwok University/BHF Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, United Kingdom

Search for other papers by T’ng Choong Kwok in
Google Scholar
PubMed Close
and
Roland H Stimson University/BHF Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, United Kingdom

Search for other papers by Roland H Stimson in
Google Scholar
PubMed Close

( Cypess et al. 2009 , van Marken Lichtenbelt et al. 2009 ). More recent analysis of large datasets support the protective effects of 18 F-FDG uptake by human BAT at room temperature against developing type 2 diabetes mellitus (T2DM), hypertension and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-23-0017
Volume/Issue:
Volume 259: Issue 1
Open access
Ryan A Lafferty Biomedical Sciences Research Institute, Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK

Search for other papers by Ryan A Lafferty in
Google Scholar
PubMed Close
,
Laura M McShane Biomedical Sciences Research Institute, Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK

Search for other papers by Laura M McShane in
Google Scholar
PubMed Close
,
Zara J Franklin Biomedical Sciences Research Institute, Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK

Search for other papers by Zara J Franklin in
Google Scholar
PubMed Close
,
Peter R Flatt Biomedical Sciences Research Institute, Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK

Search for other papers by Peter R Flatt in
Google Scholar
PubMed Close
,
Finbarr P M O’Harte Biomedical Sciences Research Institute, Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK

Search for other papers by Finbarr P M O’Harte in
Google Scholar
PubMed Close
, and
Nigel Irwin Biomedical Sciences Research Institute, Centre for Diabetes, Ulster University, Coleraine, Northern Ireland, UK

Search for other papers by Nigel Irwin in
Google Scholar
PubMed Close

Introduction It has been well established that abnormal elevation in circulating glucagon leads to an increase in hepatic glucose production and glycogen metabolism that contribute to hyperglycaemia in diabetes ( Unger 1978 ). For this reason

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-22-0106
Volume/Issue:
Volume 255: Issue 2
Open access
Alessandro Pocai Diabetes and Endocrinology, Merck Research Laboratories, Merck Sharp and Dohme Corp., 126 East Lincoln Avenue, Rahway, New Jersey 07065, USA

Search for other papers by Alessandro Pocai in
Google Scholar
PubMed Close

Introduction As the prevalence of type 2 diabetes increases, there is a medical need for additional antihyperglycemic agents that offer improved efficacy in glycemic control and tolerability. Obesity is an important risk factor for a number of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0368
Volume/Issue:
Volume 215: Issue 3
Open access
View license
Gencer Sancar German Center for Diabetes Research, Neuherberg, Germany
Department of Internal Medicine IV, Division of Diabetology, Endocrinology and Nephrology, Eberhard-Karls University of Tübingen, Tübingen, Germany
Institute for Diabetes Research and Metabolic Diseases, Helmholtz Center Munich, Eberhard-Karls University of Tübingen, Tübingen, Germany

Search for other papers by Gencer Sancar in
Google Scholar
PubMed Close
and
Andreas L Birkenfeld German Center for Diabetes Research, Neuherberg, Germany
Department of Internal Medicine IV, Division of Diabetology, Endocrinology and Nephrology, Eberhard-Karls University of Tübingen, Tübingen, Germany
Institute for Diabetes Research and Metabolic Diseases, Helmholtz Center Munich, Eberhard-Karls University of Tübingen, Tübingen, Germany

Search for other papers by Andreas L Birkenfeld in
Google Scholar
PubMed Close

fat can lead to a range of metabolic abnormalities and diseases, including dyslipidemia, metabolic dysfunction-associated steatotic liver disease (MASLD), β cell dysfunction, prediabetes, and type 2 diabetes (T2D). The common denominator of these

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-24-0115
Volume/Issue:
Volume 262: Issue 3
Open access
A Edlund Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by A Edlund in
Google Scholar
PubMed Close
,
M Barghouth Unit of Islet Pathophysiology, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by M Barghouth in
Google Scholar
PubMed Close
,
M Hühn Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Search for other papers by M Hühn in
Google Scholar
PubMed Close
,
M Abels Unit of Neuroendocrine Cell biology, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by M Abels in
Google Scholar
PubMed Close
,
J S E Esguerra Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by J S E Esguerra in
Google Scholar
PubMed Close
,
I G Mollet Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by I G Mollet in
Google Scholar
PubMed Close
,
E Svedin Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Search for other papers by E Svedin in
Google Scholar
PubMed Close
,
A Wendt Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by A Wendt in
Google Scholar
PubMed Close
,
E Renström Unit of Islet Pathophysiology, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by E Renström in
Google Scholar
PubMed Close
,
E Zhang Unit of Islet Pathophysiology, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by E Zhang in
Google Scholar
PubMed Close
,
N Wierup Unit of Neuroendocrine Cell biology, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by N Wierup in
Google Scholar
PubMed Close
,
B J Scholte Department of Cell Biology, Erasmus MC, Rotterdam, the Netherlands
Pediatric Pulmonology, Erasmus MC, Rotterdam, the Netherlands

Search for other papers by B J Scholte in
Google Scholar
PubMed Close
,
M Flodström-Tullberg Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Search for other papers by M Flodström-Tullberg in
Google Scholar
PubMed Close
, and
L Eliasson Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Search for other papers by L Eliasson in
Google Scholar
PubMed Close

reduced conductivity ( Wilke et al. 2011 ). Blood glucose abnormalities are common in CF and CF-related diabetes (CFRD) is a common secondary complication. Acquiring diabetes on the background of CF leads to an increased morbidity and mortality, and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0570
Volume/Issue:
Volume 241: Issue 1
Open access
Alyce M Martin College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia

Search for other papers by Alyce M Martin in
Google Scholar
PubMed Close
,
Emily W Sun College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia

Search for other papers by Emily W Sun in
Google Scholar
PubMed Close
, and
Damien J Keating College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia
Nutrition and Metabolism, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia

Search for other papers by Damien J Keating in
Google Scholar
PubMed Close

diseases such as type 2 diabetes (T2D) and markedly increased cardiovascular risk. Hepatic glucose production is the primary determinant of glucose homeostasis and is predominantly dictated by pancreatic insulin and glucagon. In addition, postprandial

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0399
Volume/Issue:
Volume 244: Issue 1
Open access
Hyo Youl Moon
Search for other papers by Hyo Youl Moon in
Google Scholar
PubMed Close
,
Parkyong Song BioSignal Network Laboratory, Division of Molecular and Life Sciences, Lee Gil Ya Cancer and Diabetes Institute, School of Nano-Biotechnology and Chemical Engineering, Ulsan National Institute of Science and Technology, Engineering Building 104, 689-805 Ulsan, Republic of Korea

Search for other papers by Parkyong Song in
Google Scholar
PubMed Close
,
Cheol Soo Choi BioSignal Network Laboratory, Division of Molecular and Life Sciences, Lee Gil Ya Cancer and Diabetes Institute, School of Nano-Biotechnology and Chemical Engineering, Ulsan National Institute of Science and Technology, Engineering Building 104, 689-805 Ulsan, Republic of Korea

Search for other papers by Cheol Soo Choi in
Google Scholar
PubMed Close
,
Sung Ho Ryu BioSignal Network Laboratory, Division of Molecular and Life Sciences, Lee Gil Ya Cancer and Diabetes Institute, School of Nano-Biotechnology and Chemical Engineering, Ulsan National Institute of Science and Technology, Engineering Building 104, 689-805 Ulsan, Republic of Korea

Search for other papers by Sung Ho Ryu in
Google Scholar
PubMed Close
, and
Pann-Ghill Suh
Search for other papers by Pann-Ghill Suh in
Google Scholar
PubMed Close

Introduction Excessive energy intake, including ingestion of a high-fat diet (HFD), and sedentary lifestyles cause hyperlipidemia, metabolic syndrome, and type II diabetes and are threatening to become a global epidemic ( Angulo 2007 , Lazo & Clark

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0135
Volume/Issue:
Volume 218: Issue 3
Open access
Neil Tanday Diabetes Research Centre, Ulster University, Coleraine, Londonderry, Northern Ireland

Search for other papers by Neil Tanday in
Google Scholar
PubMed Close
,
Aimee Coulter-Parkhill Diabetes Research Centre, Ulster University, Coleraine, Londonderry, Northern Ireland

Search for other papers by Aimee Coulter-Parkhill in
Google Scholar
PubMed Close
,
R Charlotte Moffett Diabetes Research Centre, Ulster University, Coleraine, Londonderry, Northern Ireland

Search for other papers by R Charlotte Moffett in
Google Scholar
PubMed Close
,
Karthick Suruli Diabetes Research Centre, Ulster University, Coleraine, Londonderry, Northern Ireland

Search for other papers by Karthick Suruli in
Google Scholar
PubMed Close
,
Vaibhav Dubey Diabetes Research Centre, Ulster University, Coleraine, Londonderry, Northern Ireland

Search for other papers by Vaibhav Dubey in
Google Scholar
PubMed Close
,
Peter R Flatt Diabetes Research Centre, Ulster University, Coleraine, Londonderry, Northern Ireland

Search for other papers by Peter R Flatt in
Google Scholar
PubMed Close
, and
Nigel Irwin Diabetes Research Centre, Ulster University, Coleraine, Londonderry, Northern Ireland

Search for other papers by Nigel Irwin in
Google Scholar
PubMed Close

Introduction Epidemiological data suggest that males are at increased risk of developing type 2 diabetes (T2D) than females, but that this sex bias is absent with onset of the menopause ( Saeedi et al. 2020 ). Clearly, there is an

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-23-0174
Volume/Issue:
Volume 259: Issue 2
Open access