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Jethro S Johnson, Monica N Opiyo, Marian Thomson, Karim Gharbi, Jonathan R Seckl, Andreas Heger, and Karen E Chapman

is protective against the adverse metabolic and pro-inflammatory effects of a high-fat diet ( Morton et al . 2004 , Wamil et al . 2011 ) and improves insulin sensitivity/glucose homeostasis in models of type 2 diabetes ( Morton et al . 2004 ). 11β

Open access

S J Brandt, M Kleinert, M H Tschöp, and T D Müller

agonist lowered ad libitum blood glucose, improved glucose tolerance and lowered circulating insulin levels ( Finan et al. 2015 a , b ), suggesting improved insulin sensitivity. The triple agonist also lowered hepatic lipid content ( Finan et al

Open access

Alyce M Martin, Emily W Sun, and Damien J Keating

Montgomery BK Marcovina SM Kahn SE 2012 Colesevelam improves oral but not intravenous glucose tolerance by a mechanism independent of insulin sensitivity and beta-cell function . Diabetes Care 1119 – 1125 . ( https://doi.org/10.2337/dc11