Search Results

You are looking at 41 - 50 of 79 items for :

  • fatty acids x
  • Refine by access: Open Access content only x
Clear All
Alvaro Souto Padron Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Alvaro Souto Padron in
Google Scholar
PubMed
Close
,
Ruy Andrade Louzada Neto Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil
Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Ruy Andrade Louzada Neto in
Google Scholar
PubMed
Close
,
Thiago Urgal Pantaleão Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Thiago Urgal Pantaleão in
Google Scholar
PubMed
Close
,
Maria Carolina de Souza dos Santos Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Maria Carolina de Souza dos Santos in
Google Scholar
PubMed
Close
,
Renata Lopes Araujo Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Renata Lopes Araujo in
Google Scholar
PubMed
Close
,
Bruno Moulin de Andrade Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Bruno Moulin de Andrade in
Google Scholar
PubMed
Close
,
Monique da Silva Leandro Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Monique da Silva Leandro in
Google Scholar
PubMed
Close
,
João Pedro Saar Werneck de Castro Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by João Pedro Saar Werneck de Castro in
Google Scholar
PubMed
Close
,
Andrea Claudia Freitas Ferreira Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Andrea Claudia Freitas Ferreira in
Google Scholar
PubMed
Close
, and
Denise Pires de Carvalho Laboratório de Fisiologia Endócrina Doris Rosenthal, Laboratório de Biologia do Exercício, Instituto de Biofísica Carlos Chagas Filho and Instituto de Pesquisa Translacional em Saúde e Ambiente na Região Amazônica (INPeTAM), CCS-Bloco G- Cidade Universitria, Ilha do Fundo, Rio de Janeiro 21949-900, Brazil

Search for other papers by Denise Pires de Carvalho in
Google Scholar
PubMed
Close

administered to control animals ( Lanni et al . 2005 ). Additionally, Lombardi et al . (2009) demonstrated that 3,5-T2 rapidly enhances the fatty acid oxidation rate in skeletal muscle. Apart from the chronic effects of 3,5-T2, acute and most likely non

Open access
Sushil K Mahata VA San Diego Healthcare System Metabolic Physiology & Ultrastructural Biology Lab., Department of Medicine, University of California at San Diego, La Jolla, CA, USA

Search for other papers by Sushil K Mahata in
Google Scholar
PubMed
Close
,
Hong Zheng Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA

Search for other papers by Hong Zheng in
Google Scholar
PubMed
Close
,
Sumana Mahata Caltech Division of Biology, California Institute of Technology, Pasadena, CA, USA

Search for other papers by Sumana Mahata in
Google Scholar
PubMed
Close
,
Xuefei Liu Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA

Search for other papers by Xuefei Liu in
Google Scholar
PubMed
Close
, and
Kaushik P Patel Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA

Search for other papers by Kaushik P Patel in
Google Scholar
PubMed
Close

-activated receptor-γ (PPARγ) coactivator 1α (PGC-1α) is a major regulator of exercise-induced phenotypic adaptation and substrate utilization. A modest (~25%) upregulation of PGC-1α improves mitochondrial biogenesis and fatty acid oxidation in healthy and insulin

Open access
K L Davies Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

Search for other papers by K L Davies in
Google Scholar
PubMed
Close
,
E J Camm Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Australia

Search for other papers by E J Camm in
Google Scholar
PubMed
Close
,
D J Smith Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

Search for other papers by D J Smith in
Google Scholar
PubMed
Close
,
O R Vaughan Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
Institute for Women’s Health, University College London, London, UK

Search for other papers by O R Vaughan in
Google Scholar
PubMed
Close
,
A J Forhead Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK

Search for other papers by A J Forhead in
Google Scholar
PubMed
Close
,
A J Murray Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

Search for other papers by A J Murray in
Google Scholar
PubMed
Close
, and
A L Fowden Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

Search for other papers by A L Fowden in
Google Scholar
PubMed
Close

of fatty acid oxidation capacity. In all protocols, leak state was measured in the presence of substrates before the addition of ADP, and the experiment concluded with the addition of cytochrome c (10 µM) to check outer mitochondrial membrane

Open access
Taira Wada Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

Search for other papers by Taira Wada in
Google Scholar
PubMed
Close
,
Yukiko Yamamoto Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

Search for other papers by Yukiko Yamamoto in
Google Scholar
PubMed
Close
,
Yukiko Takasugi Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

Search for other papers by Yukiko Takasugi in
Google Scholar
PubMed
Close
,
Hirotake Ishii Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

Search for other papers by Hirotake Ishii in
Google Scholar
PubMed
Close
,
Taketo Uchiyama Laboratory of Organic Chemistry, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

Search for other papers by Taketo Uchiyama in
Google Scholar
PubMed
Close
,
Kaori Saitoh Department of Psychiatry, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan

Search for other papers by Kaori Saitoh in
Google Scholar
PubMed
Close
,
Masahiro Suzuki Department of Psychiatry, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan

Search for other papers by Masahiro Suzuki in
Google Scholar
PubMed
Close
,
Makoto Uchiyama Department of Psychiatry, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan
Tokyo Adachi Hospital, Adachi, Tokyo, Japan

Search for other papers by Makoto Uchiyama in
Google Scholar
PubMed
Close
,
Hikari Yoshitane Department of Biological Sciences, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Search for other papers by Hikari Yoshitane in
Google Scholar
PubMed
Close
,
Yoshitaka Fukada Department of Biological Sciences, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Search for other papers by Yoshitaka Fukada in
Google Scholar
PubMed
Close
, and
Shigeki Shimba Laboratory of Health Science, School of Pharmacy, Nihon University, Funabshi, Chiba, Japan

Search for other papers by Shigeki Shimba in
Google Scholar
PubMed
Close

, total cholesterol, HDL cholesterol, LDL cholesterol, non-esterified fatty acids (NEFA) (FUJIFILM Wako Pure Chemical Co. ltd., Osaka, Japan), insulin (Morinaga Institute of Biological Science, Inc., Kanagawa, Japan), and adiponectin (Otsuka Pharmaceutical

Open access
R Prasad Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Centre for Endocrinology, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK

Search for other papers by R Prasad in
Google Scholar
PubMed
Close
,
J C Kowalczyk Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Centre for Endocrinology, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK

Search for other papers by J C Kowalczyk in
Google Scholar
PubMed
Close
,
E Meimaridou Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Centre for Endocrinology, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK

Search for other papers by E Meimaridou in
Google Scholar
PubMed
Close
,
H L Storr Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Centre for Endocrinology, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK

Search for other papers by H L Storr in
Google Scholar
PubMed
Close
, and
L A Metherell Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Centre for Endocrinology, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK

Search for other papers by L A Metherell in
Google Scholar
PubMed
Close

distribution and retention of selenium in the rat . Journal of Nutrition 114 1289 – 1296 . Brites P Mooyer PA El Mrabet L Waterham HR Wanders RJ 2009 Plasmalogens participate in very-long-chain fatty acid-induced pathology . Brain 132

Open access
Gisela Helfer School of Chemistry and Biosciences, University of Bradford, Bradford, UK

Search for other papers by Gisela Helfer in
Google Scholar
PubMed
Close
and
Qing-Feng Wu State Key Laboratory of Molecular Development Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

Search for other papers by Qing-Feng Wu in
Google Scholar
PubMed
Close

). Diabetes Recently, novel adipokines such as vaspin, omentin, retinal-binding protein-4, fibroblast growth factor 21, adipocyte fatty acid-binding protein and dipeptidyl peptidase 4 were found to associate with insulin resistance and T2DB in humans

Open access
T V Novoselova Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by T V Novoselova in
Google Scholar
PubMed
Close
,
R Larder University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by R Larder in
Google Scholar
PubMed
Close
,
D Rimmington University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by D Rimmington in
Google Scholar
PubMed
Close
,
C Lelliott Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by C Lelliott in
Google Scholar
PubMed
Close
,
E H Wynn Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by E H Wynn in
Google Scholar
PubMed
Close
,
R J Gorrigan Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by R J Gorrigan in
Google Scholar
PubMed
Close
,
P H Tate Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by P H Tate in
Google Scholar
PubMed
Close
,
L Guasti Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by L Guasti in
Google Scholar
PubMed
Close
,
The Sanger Mouse Genetics Project Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by The Sanger Mouse Genetics Project in
Google Scholar
PubMed
Close
,
S O’Rahilly University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by S O’Rahilly in
Google Scholar
PubMed
Close
,
A J L Clark Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by A J L Clark in
Google Scholar
PubMed
Close
,
D W Logan Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by D W Logan in
Google Scholar
PubMed
Close
,
A P Coll University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by A P Coll in
Google Scholar
PubMed
Close
, and
L F Chan Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by L F Chan in
Google Scholar
PubMed
Close

at 22°C followed by incubation at 4°C overnight with the primary antibody: anti-ACTB antibody 1/10,000 (Abcam), anti-UCP1 1/5000 (Abcam) and antibodies for Fatty Acid and Lipid Metabolism and Lipolysis Activation (8334, 8335 Cell Signaling Technology

Open access
Alessandro Pocai Diabetes and Endocrinology, Merck Research Laboratories, Merck Sharp and Dohme Corp., 126 East Lincoln Avenue, Rahway, New Jersey 07065, USA

Search for other papers by Alessandro Pocai in
Google Scholar
PubMed
Close

increases thermogenesis, satiety, lipolysis, fatty acid oxidation, and ketogenesis ( Salter 1960 , Salter et al . 1960 , Penick & Hinkle 1961 , Langhans et al . 1982 , Habegger et al . 2010 , Jones et al . 2012 ). A critical physiological role of

Open access
Gulizar Issa Ameen Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

Search for other papers by Gulizar Issa Ameen in
Google Scholar
PubMed
Close
and
Silvia Mora Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

Search for other papers by Silvia Mora in
Google Scholar
PubMed
Close

utilization and fatty acid activating AMP-activated protein kinase. Nature Medicine 8 1288 – 1295 . ( https://doi.org/10.1038/nm788 ) 12368907 10.1038/nm788 Yang C Mora S Ryder JW Coker KJ Hansen P Allen LA Pessin JE 2001

Open access
Elisa Villalobos University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

Search for other papers by Elisa Villalobos in
Google Scholar
PubMed
Close
,
Allende Miguelez-Crespo University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Allende Miguelez-Crespo in
Google Scholar
PubMed
Close
,
Ruth A Morgan University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Scotland’s Rural College, The Roslin Institute, Easter Bush Campus, United Kingdom

Search for other papers by Ruth A Morgan in
Google Scholar
PubMed
Close
,
Lisa Ivatt University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Lisa Ivatt in
Google Scholar
PubMed
Close
,
Mhairi Paul University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Mhairi Paul in
Google Scholar
PubMed
Close
,
Joanna P Simpson University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Joanna P Simpson in
Google Scholar
PubMed
Close
,
Natalie Z M Homer University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Natalie Z M Homer in
Google Scholar
PubMed
Close
,
Dominic Kurian The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom

Search for other papers by Dominic Kurian in
Google Scholar
PubMed
Close
,
Judit Aguilar The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom

Search for other papers by Judit Aguilar in
Google Scholar
PubMed
Close
,
Rachel A Kline The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom

Search for other papers by Rachel A Kline in
Google Scholar
PubMed
Close
,
Thomas M Wishart The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom

Search for other papers by Thomas M Wishart in
Google Scholar
PubMed
Close
,
Nicholas M Morton University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Centre for Systems Health and Integrated Metabolic Research, Nottingham Trent University, Nottingham, United Kingdom

Search for other papers by Nicholas M Morton in
Google Scholar
PubMed
Close
,
Roland H Stimson University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Roland H Stimson in
Google Scholar
PubMed
Close
,
Ruth Andrew University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Ruth Andrew in
Google Scholar
PubMed
Close
,
Brian R Walker University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom

Search for other papers by Brian R Walker in
Google Scholar
PubMed
Close
, and
Mark Nixon University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Search for other papers by Mark Nixon in
Google Scholar
PubMed
Close

TissueLyser II (Qiagen) and 5 mm stainless-steel beads (30 Hz, three cycles of 15 s). Protein concentration was quantified using a bicinchoninic acid (BCA) assay (Thermo Scientific). Extracted proteins (25 µg) were resolved by SDS-PAGE, using Criterion TGX

Open access