Search Results

You are looking at 1 - 10 of 23 items for :

  • "Glucose metabolism" x
  • Open access x
Clear All
Open access

Corinne Caillaud, Mie Mechta, Heidi Ainge, Andreas N Madsen, Patricia Ruell, Emilie Mas, Catherine Bisbal, Jacques Mercier, Stephen Twigg, Trevor A Mori, David Simar and Romain Barrès

as a regulator involved in glucose metabolism. Results of early studies carried out of patients with end-stage renal disease (ESRD) indicated that EPO not only treated anemia but also improved insulin sensitivity ( Borissova et al . 1993 , Mak 1996

Open access

Nikolaos Nikolaou, Anastasia Arvaniti, Nathan Appanna, Anna Sharp, Beverly A Hughes, Dena Digweed, Martin J Whitaker, Richard Ross, Wiebke Arlt, Trevor M Penning, Karen Morris, Sherly George, Brian G Keevil, Leanne Hodson, Laura L Gathercole and Jeremy W Tomlinson

decreased following dexamethasone treatment, indicative of decreased AKR1D1 activity (C). Data are presented as mean ±  s.e. of n  = 14 participants, *** P  < 0.001. AKR1D1 knockdown alters glucose metabolism gene expression through FXR, GR

Open access

Jeffrey Friedman

stimulates glucose metabolism in WT mice independent of weight loss and that it can improve the diabetes of lipodystrophic mice independent of insulin ( Kamohara et al 1997 , Asilmaz et al . 2004 ). This raised the possibility that leptin might show

Open access

Alessandro Pocai

Sequence comparisons of GLP1(7–36) amide, glucagon(1–29), glicentin, OXM, and OXMQ3E. OXM and glucose metabolism Studies have suggested that OXM may play a role in glucose homeostasis. Chronic treatment with OXM results in superior weight-lowering and

Open access

Gisela Helfer and Qing-Feng Wu

. 2007 ). Subsequent studies revealed that chemerin acts on its receptor CMKLR1 to affect adipogenesis, angiogenesis and inflammation in adipose tissue. Beyond the lipid metabolism, chemerin also influences the dysregulation of glucose metabolism

Open access

Alyce M Martin, Emily W Sun and Damien J Keating

and intracellular glucose metabolism, which leads to closure of K ATP channels and further depolarisation and exocytosis ( Reimann et al . 2008 , Gorboulev et al . 2012 , Kuhre et al . 2014 a , Sun et al . 2017 ). Additional mechanisms

Open access

Kunihisa Hamano, Yuko Nakagawa, Yoshiaki Ohtsu, Longfei Li, Johan Medina, Yuji Tanaka, Katsuyoshi Masuda, Mitsuhisa Komatsu and Itaru Kojima

activation of the glucose-sensing receptor led to an increase in [ATP] c by facilitating glucose metabolism ( Nakagawa et al . 2014 ). Accordingly, artificial sweeteners increase [ATP] c even though they do not serve as substrates for glycolysis. We next

Open access

Jin-Ran Chen, Oxana P Lazarenko, Haijun Zhao, Alexander W Alund and Kartik Shankar

and to program gene expression in key metabolic pathways, such as fatty acids and glucose metabolism ( Levin & Govek 1998 , King 2006 , Shankar et al . 2008 , Geraghty et al . 2016 ). Emerging evidence suggests that maternal obesity caused by

Open access

Nami Kim, Jung Ok Lee, Hye Jeong Lee, Yong Woo Lee, Hyung Ip Kim, Su Jin Kim, Sun Hwa Park, Chul Su Lee, Sun Woo Ryoo, Geum-Sook Hwang and Hyeon Soo Kim

motif that affects glucose metabolism. One study compared the antitumor activity of curcumin and isoeugenol ( Fujisawa et al . 2004 ). This study showed that curcumin exerted better cytotoxic effects against cancer cells than isoeugenol. Because only a

Open access

T Mracek, D Gao, T Tzanavari, Y Bao, X Xiao, C Stocker, P Trayhurn and C Bing

liver glucose metabolism in ob/ob animals. A previous study has shown that hyperglycaemia in ob/ob mice is characterised by decreased phosphoenolpyruvate carboxykinase mRNA and increased Gapdh mRNA levels in the liver ( Ferber et al . 1994 ). We