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Clocks for all seasons: unwinding the roles and mechanisms of circadian and interval timers in the hypothalamus and pituitary

Shona Wood and Andrew Loudon

-expressing cells of the PT lack the TRH receptor, therefore cannot be regulated by a conventional hypothalamus peptide (TRH). The PT thyrotrophs are organised with an internal cistern-like structure, perhaps allowing the action of TSH on hypothalamic cells