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rhythms ( Kohsaka et al. 2007 ). The levels of several hormones and cytokines show a circadian rhythm ( Andrews & Folk 1964 , Barter et al. 1971 , Vaughan et al. 1976 , Kaneko et al. 1980 , Arvidson et al. 1994 , Sinha et al. 1996
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The Lawson Health Research Institute and the Children's Health Research Institute, London, Ontario, Canada
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terms are shown at maximum. Each bubble is the -log 10 ( P -value) for the respective term and is sized according to the gene ratio. Across the GO:BP, GO:CC, and KEGG enriched terms, we observed common terms related to circadian rhythm
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thyroid hormones compared to control rats, and based on the mean concentrations, it amounted to 7.7-fold for T4, 23-fold for free T4 and two-fold for T3, respectively ( Fig. 4D, E and F ). Furthermore, daily circadian rhythms in the thyroid hormones
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cones ( Lucas & Foster 1999 ), indicating a role for the non-image-forming photoreceptor OPN4 in melatonin inhibition by light and circadian rhythms. The OPN4 photoreceptor is involved in both circadian re-setting mechanisms and pupillary light
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preoptic area (POA; de la Iglesia et al . 1995 ). Transmission of the time-of-day signal from the SCN to CRH- and GnRH-synthesizing neurons is thought to be involved in the entrainment of the circadian rhythm governing the activities of the HPA and HPO
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. Holmes MC French KL Seckl JR 1995 Modulation of serotonin and corticosteroid receptor gene expression in the rat hippocampus with circadian rhythm and stress . Molecular Brain Research 28 186 – 192 . ( doi:10.1016/0169-328X(94)00207-U
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serotonin and corticosteroid receptor gene expression in the rat hippocampus with circadian rhythm and stress . Molecular Brain Research 28 186 – 192 . Horton R Pasupuletti V Antonipillai I 1993 Androgen induction of steroid 5α-reductase may
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, revealing key species-specific differences that emphasize the importance of studying BAT in humans ( Broeders et al. 2015 , Ramage et al. 2016 , Blondin et al. 2020 ). In addition, human brown adipocytes have been used to reveal the circadian rhythm
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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. ( https://doi.org/10.1210/jc.2014-3911 ) 25658017 Rao R Somvanshi P Klerman EB Marmar C Doyle 3rd FJ 2021 Modeling the influence of chronic sleep restriction on cortisol circadian rhythms, with implications for metabolic disorders
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erythrocytes correlates well with the characterised rhythmicity of DHEAS and cortisol ( Goncharova et al . 2008 b ). Additionally, a similar age-related flattening of these SOD circadian rhythms has been observed, indicating a possible regulatory effect of