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, polyploidization, and changes in gene expression including increased expression of decidual prolactin, IGF-binding protein 1 (IGFBP1) and fibroblast growth factor (FGF). Mice lacking genes that control decidualization cannot maintain pregnancy ( Laws et al. 2008
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Endometrial glands are essential for blastocyst implantation and decidualization in the mouse uterus . Biology of Reproduction 88 93 . ( https://doi.org/10.1095/biolreprod.113.107631 ) 23407384 Franco HL Dai D Lee KY Rubel CA Roop D Boerboom
Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
Wuhan Clinical Research Center for Reproductive Science and Birth Health, Wuhan Hubei Province, PR China
Department of Gynaecology and Obstetrics, Sinopharm Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei Province, PR China
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Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
Wuhan Clinical Research Center for Reproductive Science and Birth Health, Wuhan Hubei Province, PR China
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Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
Wuhan Clinical Research Center for Reproductive Science and Birth Health, Wuhan Hubei Province, PR China
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Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan Hubei Province, PR China
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orchestrating endometrial receptivity during embryo implantation. Studies reveal that specific KLF family members, including KLF12, exert a negative regulatory influence on human endometrial receptivity. Notably, KLF12 inhibits the decidualization of human
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Kangasniemi M Liakka A Spitzer T Tran N Huddleston H Irwin JC Giudice LC 2015 Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote
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– 2296 . ( doi:10.1210/en.2003-1606 ) Lockwood CJ Nemerson Y 1993 Progestational regulation of human endometrial stromal cell tissue factor expression during decidualization . Journal of Clinical Endocrinology and Metabolism 76 231 – 236