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L Nicol
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M-O Faure MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Centre for Reproductive Biology, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK

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J R McNeilly
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J Fontaine MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Centre for Reproductive Biology, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK

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C Taragnat MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Centre for Reproductive Biology, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK

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A S McNeilly
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. Liu F Austin DA Mellon PL Olefsky JM Webster NJ 2002 GnRH activates ERK1/2 leading to the induction of c-fos and LHβ protein expression in LβT2 cells . Molecular Endocrinology 16 419 – 434 . Lou J Tu Y Li S Manske PR 2000 Involvement

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0542
Volume/Issue:
Volume 196: Issue 3
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David M Cartwright Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Lucy A Oakey Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Rachel S Fletcher Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Craig L Doig Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
School of Science and Technology, Nottingham Trent University, Nottingham, UK

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Silke Heising Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Dean P Larner Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Daniela Nasteska Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Caitlin E Berry Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Sam R Heaselgrave Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Christian Ludwig Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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David J Hodson Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Gareth G Lavery Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

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Antje Garten Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
Pediatric Research Center, Hospital for Child and Adolescent Medicine, Leipzig University, Leipzig, Germany

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al. 2019 ) were conducted with male C57BL/6J or C57BL/6JRj mice (B6J), a commonly used mouse model to study the effects of diet-induced obesity and glucose intolerance. A limitation of using these mice for metabolic studies is a deficiency in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-21-0123
Volume/Issue:
Volume 251: Issue 1
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Nan Yang Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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Giorgio Caratti Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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Louise M Ince Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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Toryn M Poolman Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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Peter J Trebble Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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Cathy M Holt Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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David W Ray Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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Laura C Matthews Manchester Centre for Nuclear Hormone Research in Disease and Institute of Human Development, Institute of Cardiovascular Sciences, Faculty of Medical and Human Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK

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ApoE −/− mice have been described previously ( Plump et al . 1992 ). Transgenic and WT (C57BL/6) mice were routinely housed in 12 h light:12 h darkness (L:D) cycles with ad libitum access to food and water in a pathogen-free animal facility at the

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DOI:
https://doi.org/10.1530/JOE-14-0456
Volume/Issue:
Volume 223: Issue 2
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Carolina Gaudenzi Neuro-Epigenetics Research Group, Dorothy Hodgkin Building, University of Bristol, Bristol, United Kingdom

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Karen R Mifsud Neuro-Epigenetics Research Group, Dorothy Hodgkin Building, University of Bristol, Bristol, United Kingdom

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Johannes M H M Reul Neuro-Epigenetics Research Group, Dorothy Hodgkin Building, University of Bristol, Bristol, United Kingdom

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Endocrinology 15 1586 – 1598 . ( https://doi.org/10.1210/mend.15.9.0689 ) Zhou HL Hinman MN Barron VA Geng C Zhou G Luo G Siegel RE & Lou H 2011 Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-22-0293
Volume/Issue:
Volume 258: Issue 2
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Lisa Rice Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine
Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Charlotte E Waters Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Jennifer Eccles Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Helen Garside Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Paula Sommer Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Paul Kay Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Fiona H Blackhall Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Leo Zeef Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Brian Telfer Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Ian Stratford Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Rob Clarke Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Dave Singh Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Adam Stevens Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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Anne White Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine
Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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David W Ray Faculty of Medical and Human Sciences, Faculty of Life Sciences, Faculty of Medical and Human Sciences, School of Medicine

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adding 3 μg of each into 48 μl annealing buffer (100 mM sodium chloride, 50 mM HEPES (pH 7.4)). The mixture was then incubated at 90 °C for 4 min, followed by 70 °C for 10 min. The mixture was then slowly cooled to 10 °C. The shRNA sequences were then

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0019
Volume/Issue:
Volume 198: Issue 3
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Pauline Campos College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, UK

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Jamie J Walker College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, UK
EPSRC Centre for Predictive Modelling in Healthcare, University of Exeter, Exeter, UK
Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, UK

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Patrice Mollard IGF, University of Montpellier, CNRS, INSERM, Montpellier, France

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newly discovered genetic mutations result in phenotypic changes (B) can be elucidated using in vivo deep brain imaging. Researchers will greatly benefit from real-time visualisation of single neuron calcium activity (C), population calcium activity (D

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-20-0028
Volume/Issue:
Volume 246: Issue 2
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Samrin Kagdi Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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Sulayman A Lyons Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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Jacqueline L Beaudry Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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provided a subcutaneous GIP infusion, they showed an increase in NEFA levels during the first 3 h, without changes in fasting plasma levels of C-peptide or insulin ( Heimburger et al. 2022 ). GIP infusions initially lowered the respiratory exchange ratio

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DOI:
https://doi.org/10.1530/JOE-23-0361
Volume/Issue:
Volume 261: Issue 3
Open access