Search Results

You are looking at 1 - 8 of 8 items for :

  • TRH receptor x
  • Refine by Access: Open Access content only x
Clear All
Open access

T V Novoselova, R Larder, D Rimmington, C Lelliott, E H Wynn, R J Gorrigan, P H Tate, L Guasti, The Sanger Mouse Genetics Project, S O’Rahilly, A J L Clark, D W Logan, A P Coll, and L F Chan

Introduction Melanocortin receptor accessory protein (MRAP) and its paralogue MRAP2 are a recently identified class of small, single-pass transmembrane domain accessory proteins ( Chan et al . 2009 , Novoselova et al . 2013 ). Both MRAP and

Open access

Nadia Schoenmakers, Kyriaki S Alatzoglou, V Krishna Chatterjee, and Mehul T Dattani

Diagramatic representation of the hypothalamic–pituitary–thyroid axis with positive regulation (black) predominantly mediated by thyrotropin-releasing hormone (TRH) and negative (grey) feedback influences, predominantly mediated by thyroid hormone receptor (TR

Open access

Pauline Campos, Jamie J Walker, and Patrice Mollard

trigger large and rapid calcium (Ca 2+ ) influx through voltage-gated channels. AP firing can therefore be assessed by measuring changes in concentrations of intracellular Ca 2+ ( Yasuda et al. 2004 ). Similarly, activation of neurotransmitter receptors

Open access

J Fahrenkrug, B Georg, J Hannibal, and H L Jørgensen

established ( Rookh et al . 1979 , Jordan et al . 1980 , Ottenweller & Hedge 1982 , Wong et al . 1983 , Kalsbeek et al . 2000 , Guo et al . 2015 ). Nerve fibres originating in the SCN innervating thyroid-releasing hormone (TRH) neurons in the

Open access

David R Grattan

the portal blood accounted for changes in prolactin secretion in various physiological conditions ( Ben-Jonathan et al . 1977 , 1980 , Gibbs & Neill 1978 , De Greef & Neill 1979 ). Dopamine receptors were identified on lactotroph cells in the

Open access

Shona Wood and Andrew Loudon

β sub-units of thyroid-stimulating hormone (TSH). These cells lack receptors for the hypothalamic thyrotropin-releasing hormone (TRH) ( Bockmann et al . 1997 ), and do not respond to conventional hypothalamic outputs. In mammals, the MT1 receptor co

Open access

Alvaro Souto Padron, Ruy Andrade Louzada Neto, Thiago Urgal Pantaleão, Maria Carolina de Souza dos Santos, Renata Lopes Araujo, Bruno Moulin de Andrade, Monique da Silva Leandro, João Pedro Saar Werneck de Castro, Andrea Claudia Freitas Ferreira, and Denise Pires de Carvalho

TSH regulation, strongly support the hypothesis that 3,5-T2 functions as an agonist of the β isoform of thyroid hormone receptor (TR) in vivo . Figure 4 Type 1 (D1) and type 2 (D2) iodothyronine deiodinase activities in control rats and rats treated

Open access

Dominik Simon Botermann, Nadine Brandes, Anke Frommhold, Ina Heß, Alexander Wolff, Arne Zibat, Heidi Hahn, Rolf Buslei, and Anja Uhmann

binding of Hh ligands (e.g. mammalian Sonic, Indian or Desert Hh) to the receptor protein Patched1 (Ptch). This releases the inhibition of Smoothened (Smo), which results in translocation of Smo into the primary cilium and nuclear translocation of