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S Schmidt Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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A Hommel Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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V Gawlik Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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R Augustin Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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N Junicke Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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S Florian Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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M Richter Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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D J Walther Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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D Montag Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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H-G Joost Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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A Schürmann Toxicology, Department of Human Molecular Genetics, Research Group Neurogenetics, Departments of

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). GLUT3 is also expressed in other cells (sperm, pre- and post-implantation embryo circulating white blood cells, and carcinoma cells) where it triggers the specific requirements for glucose ( Simpson et al . 2008 ). Several studies have demonstrated

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0262
Volume/Issue:
Volume 200: Issue 1
Open access
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Antonia Hufnagel University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

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Laura Dearden University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

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Denise S Fernandez-Twinn University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

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Susan E Ozanne University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke’s Hospital, Cambridge, Cambridgeshire, UK

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placenta at term ( Nelson et al. 1978 ). The glycocalyx, a network of glycoproteins, is present on the maternal microvillous membrane and has been proposed to play a role in the regulation of transport across the syncytiotrophoblast ( Fabre-Gray et al

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-21-0332
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Volume 253: Issue 2
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Sara Della Torre Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

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Gianpaolo Rando Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

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Clara Meda Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

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Paolo Ciana Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy

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Luisa Ottobrini Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Adriana Maggi Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

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active in most reproductive and non-reproductive tissue cells ( Ciocca & Roig 1995 , Maggi et al. 2004 , Bookout et al. 2006 ). Their expression and transcriptional activity in the course of embryo development is less studied ( Brandenberger et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0003
Volume/Issue:
Volume 238: Issue 3
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Seokwon Jo Department of Integrative Biology & Physiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA

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Emilyn U Alejandro Department of Integrative Biology & Physiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA

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-cells arise from progenitor cells located in the endoderm of the developing embryo. These progenitor cells differentiate into islet cells, including insulin-producing beta-cells, which comprise the endocrine pancreas. This process is regulated by a complex

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https://doi.org/10.1530/JOE-23-0069
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Volume 259: Issue 3
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Denys deCatanzaro Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, Ontario, Canada

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Tyler Pollock Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, Ontario, Canada

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leukocytes including neutrophils, eosinophils, macrophages and uterine natural killer cells ( Tibbetts et al . 1999 , Hunt et al . 2000 ). E 2 also facilitates transport of preimplantation embryos from the oviduct to the uterus ( Roblero & Garavagno 1979

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0247
Volume/Issue:
Volume 231: Issue 3
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Antonio Gázquez Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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Francisca Rodríguez Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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María Sánchez-Campillo Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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Lidia E Martínez-Gascón Department of Clinical Analysis, Biomedical Research Institute of Murcia, Santa Lucia General University Hospital, Murcia, Spain

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Marino B Arnao Department of Plant Biology (Plant Physiology), University of Murcia, Murcia, Spain

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Pedro Saura-Garre Department of Clinical Psychology, University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain

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María D Albaladejo-Otón Department of Clinical Analysis, Biomedical Research Institute of Murcia, Santa Lucia General University Hospital, Murcia, Spain

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Elvira Larqué Department of Physiology, CEIR Campus Mare Nostrum, University of Murcia, Biomedical Research Institute of Murcia, Murcia, Spain

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transport of docosahexaenoic acid (22:6 n-3, DHA) by GDM ( Herrera & Ortega-Senovilla 2010 , Leveille et al. 2018 ), likely as a consequence of alterations in fatty acids (FA) transport proteins related to phospholipids transfer such as the major

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-20-0617
Volume/Issue:
Volume 251: Issue 1
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Gulizar Issa Ameen Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

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Silvia Mora Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

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Introduction Casitas b-lymphoma (Cbl) is a proximal insulin receptor adaptor protein identified as necessary for insulin-mediated activation of glucose transport in adipocytes ( Baumann et al . 2000 , Chiang et al . 2001 , Chang et al

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https://doi.org/10.1530/JOE-17-0359
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Volume 236: Issue 1
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K A Staines
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A S Pollard
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I M McGonnell
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C Farquharson Comparative Biomedical Sciences, Roslin Institute and R(D)SVS, The Royal Veterinary College, Royal College Street, London NW1 0TU, UK

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A A Pitsillides
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184 447 – 456 . Arkill KP Winlove CP 2008 Solute transport in the deep and calcified zones of articular cartilage . Osteoarthritis and Cartilage 16 708 – 714 . ( doi:10.1016/j.joca.2007.10.001 ) Ballock RT O'Keefe RJ 2003

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https://doi.org/10.1530/JOE-13-0276
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Volume 219: Issue 1
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Nadia Schoenmakers University of Cambridge Metabolic Research Laboratories, Developmental Endocrinology Research Group, Wellcome Trust‐Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Level 4, PO Box 289, Hills Road, Cambridge CB2 0QQ, UK

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Kyriaki S Alatzoglou University of Cambridge Metabolic Research Laboratories, Developmental Endocrinology Research Group, Wellcome Trust‐Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Level 4, PO Box 289, Hills Road, Cambridge CB2 0QQ, UK

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V Krishna Chatterjee University of Cambridge Metabolic Research Laboratories, Developmental Endocrinology Research Group, Wellcome Trust‐Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Level 4, PO Box 289, Hills Road, Cambridge CB2 0QQ, UK

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Mehul T Dattani University of Cambridge Metabolic Research Laboratories, Developmental Endocrinology Research Group, Wellcome Trust‐Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Level 4, PO Box 289, Hills Road, Cambridge CB2 0QQ, UK

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hormone-producing cell types ( Lanctot et al . 1999 ). Pitx1 null embryos have normal pituitary morphogenesis; however, at birth the number of thyrotropes and gonadotropes are reduced. This absence of early defects may in part be explained by the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-15-0341
Volume/Issue:
Volume 227: Issue 3
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Shisan Xu Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Fangjing Xie Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Li Tian Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Samane Fallah Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Fatemeh Babaei Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Sinai H C Manno Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Francis A M Manno III School of Biomedical Engineering, Faculty of Engineering, University of Sydney, Sydney, New South Wales, Australia

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Lina Zhu Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Kin Fung Wong Department of Biomedical Engineering, Polytechnic University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Yimin Liang Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Rajkumar Ramalingam Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Lei Sun Department of Biomedical Engineering, Polytechnic University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Xin Wang Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Robert Plumb Waters Technologies Corporation, Milford, Massachusetts, USA

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Lee Gethings Waters Technologies Corporation, Milford, Massachusetts, USA

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Yun Wah Lam Department of Chemistry, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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Shuk Han Cheng Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong SAR, People’s Republic of China
State Key Laboratory of Marine Pollution (SKLMP) at City University of Hong Kong, Hong Kong SAR, People’s Republic of China
Department of Materials Science and Engineering, College of Science and Engineering, City University of Hong Kong, Hong Kong SAR, People’s Republic of China

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hormones in zebrafish cardiac development and function. Inhibition of E2 synthesis treatment with aromatase enzyme induces a phenotype similar to congestive heart failure and tamponade in zebrafish embryos ( Allgood Jr et al . 2013 ). These conditions are

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0413
Volume/Issue:
Volume 245: Issue 1
Open access