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Geoffrey L Hammond

aldosterone, which is bound primarily by albumin, other steroid hormones bind to CBG and SHBG with high (nM) affinity and specificity, with SHBG binding the major androgens and estrogens, and CBG binding the glucocorticoids and progesterone, preferentially

Open access

Virginia Rider, Alex Talbott, Anuradha Bhusri, Zach Krumsick, Sierra Foster, Joshua Wormington, and Bruce F Kimler

Introduction In adult female mammals, the uterus undergoes remodeling with a regular cyclicity under the control of the sex hormones, progesterone and estradiol ( Bell 1983 , Pawar et al . 2014 ). In the rodent uterus, estradiol stimulates

Open access

Ya-Li Yang, Li-Rong Ren, Li-Feng Sun, Chen Huang, Tian-Xia Xiao, Bao-Bei Wang, Jie Chen, Brian A Zabel, Peigen Ren, and Jian V Zhang

. Discussion Follicular development directly influences the number of ova and ovarian endocrine functions, such as secretion of steroid hormones (estrogen, progesterone, and testosterone) ( Su & Eppig 2002 ). Theca cells, granulosa cells, and oocytes are the

Open access

Yoshihiro Joshua Ono, Yoshito Terai, Akiko Tanabe, Atsushi Hayashi, Masami Hayashi, Yoshiki Yamashita, Satoru Kyo, and Masahide Ohmichi

stromal cells. However, we confirmed that the CRL-4003 cells were useful in identifying both the hormonal status (estrogen receptor (ER) and progesterone receptor (PR)) and expression of DCN mRNA treated with dienogest in primary cultured endometriotic

Open access

Denys deCatanzaro and Tyler Pollock

puberty in female mice: confirmation of the role of estrogen . Endocrinology 96 511 – 514 . ( doi:10.1210/endo-96-2-511 ) Butcher RL Collins WE Fugo NW 1974 Plasma concentration of LH, FSH, prolactin, progesterone and estradiol-17β

Open access

Ekaterine Tskitishvili, Christel Pequeux, Carine Munaut, Renaud Viellevoye, Michelle Nisolle, Agnes Noël, and Jean-Michel Foidart

Molecular Biology 110 138 – 143 . ( doi:10.1016/j.jsbmb.2008.03.027 ) Irwin RW Yao J Hamilton RT Cadenas E Brinton RD Nilsen J 2008 Progesterone and estrogen regulate oxidative metabolism in brain mitochondria

Open access

Shisan Xu, Fangjing Xie, Li Tian, Samane Fallah, Fatemeh Babaei, Sinai H C Manno, Francis A M Manno III, Lina Zhu, Kin Fung Wong, Yimin Liang, Rajkumar Ramalingam, Lei Sun, Xin Wang, Robert Plumb, Lee Gethings, Yun Wah Lam, and Shuk Han Cheng

cardiomyocytes are sexually dimorphic ( Isensee et al . 2008 , Tsuji et al . 2017 ), and estrogen receptor expression is deregulated in some cardiomyopathies ( Mahmoodzadeh et al . 2006 ). Despite the apparent involvement of estrogen in CVD, clinical

Open access

Karin L Gustafsson, Sofia Movérare-Skrtic, Helen H Farman, Cecilia Engdahl, Petra Henning, Karin H Nilsson, Julia M Scheffler, Edina Sehic, Ulrika Islander, Ellis Levin, Claes Ohlsson, and Marie K Lagerquist

Introduction Estrogen treatment protects against osteoporosis-related fractures, has favorable effects on several metabolic parameters, and alleviates postmenopausal symptoms. However, due to adverse effects, estrogen treatment is avoided

Open access

Georgina G J Hazell, Song T Yao, James A Roper, Eric R Prossnitz, Anne-Marie O'Carroll, and Stephen J Lolait

Society for Neuroendocrinology meeting in Bristol (September, 2008) and the Winter Neuropeptide Conference in Colorado (February, 2009). References Ábrahám I Todman MG Korach KS Herbison AE 2004 Critical in vivo roles for classical estrogen

Open access

Carmen Corciulo, Julia M Scheffler, Piotr Humeniuk, Alicia Del Carpio Pons, Alexandra Stubelius, Ula Von Mentzer, Christina Drevinge, Aidan Barrett, Sofia Wüstenhagen, Matti Poutanen, Claes Ohlsson, Marie K Lagerquist, and Ulrika Islander

-Zeinstra 2019 ). Epidemiological studies associate menopause with articular cartilage degeneration, OA severity, and unsuccessful joint replacement. The decline of sex steroids after menopause, in particular estrogens, has been investigated as responsible for