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Open access

Georgina G J Hazell, Song T Yao, James A Roper, Eric R Prossnitz, Anne-Marie O'Carroll, and Stephen J Lolait

protein-coupled receptor from rat lung . Biochemical and Biophysical Research Communications 8 190 – 193 . Bossmar T Forsling M Akerlund M 1995 Circulating oxytocin and vasopressin is influenced by ovarian steroid replacement in women

Open access

David R Grattan

) Oxytocin secretion Marked change in firing pattern, generation of ‘burst’ firing to facilitate parturition and milk ejection Prolactin receptors on oxytocin neurons, and acute inhibitory effects on activity Kokay et al . (2006) and Sapsford et al

Open access

Anne-Marie O'Carroll, Gillian M Howell, Emma M Roberts, and Stephen J Lolait

paradigm of endocrine secretion . European Journal of Biochemistry 259 3 – 17 . Lee B Yang C Chen TH al Azawi N Hsu WH 1995 Effect of AVP and oxytocin on insulin release: involvement of V1b receptors . American Journal of Physiology

Open access

Emma M Roberts, Michael J F Newson, George R Pope, Rainer Landgraf, Stephen J Lolait, and Anne-Marie O'Carroll

Introduction Apelin, a novel 36 amino acid peptide originally isolated from extracts of bovine stomach ( Tatemoto et al . 1998 ), mediates its actions through the G protein-coupled (GPCR) apelin receptor (APJ; APLNR as given in the MGI Database

Open access

Michael J F Newson, Emma M Roberts, George R Pope, Stephen J Lolait, and Anne-Marie O'Carroll

Introduction The apelin peptide, isolated from extracts of bovine stomach ( Tatemoto et al . 1998 ), selectively binds to the G-protein-coupled apelin receptor (APJ; O'Dowd et al . 1993 ). Apelin, a 36-amino acid peptide, is derived from a 77

Open access

Helen L Jeanes, Caroline Tabor, Darcey Black, Antwan Ederveen, and Gillian A Gray

–reperfusion injury in ovariectomised rats ( Squadrito et al . 1997 , Jeanes et al . 2007 ). There are two known oestrogen receptors (ERs), ERα and ERβ. The receptors are members of the steroid hormone receptor family with distinct tissue distribution and

Open access

F Wahab, M Shahab, and R Behr

). Recently, GnIH receptor (GnIHR) antagonist, RF9, injection has markedly reversed fasting-induced quiescent of the reproductive axis in the male adult rhesus monkey ( Batool et al . 2014 ). In contrast, an anorexigenic effect of KP has been noted ( Stengel

Open access

T V Novoselova, R Larder, D Rimmington, C Lelliott, E H Wynn, R J Gorrigan, P H Tate, L Guasti, The Sanger Mouse Genetics Project, S O’Rahilly, A J L Clark, D W Logan, A P Coll, and L F Chan

Introduction Melanocortin receptor accessory protein (MRAP) and its paralogue MRAP2 are a recently identified class of small, single-pass transmembrane domain accessory proteins ( Chan et al . 2009 , Novoselova et al . 2013 ). Both MRAP and

Open access

Dawn E W Livingstone, Emma M Di Rollo, Chenjing Yang, Lucy E Codrington, John A Mathews, Madina Kara, Katherine A Hughes, Christopher J Kenyon, Brian R Walker, and Ruth Andrew

Ppia in addition for pituitary); the respective means of the reference genes did not differ between groups. Table 1 Assay details for real-time PCR. ABI assay numbers: cyclophilin ( Ppia ), Mm02342429_g1; corticotrophin-releasing hormone receptor 1

Open access

David M Golding, Daniel J Rees, Jennifer R Davies, Dinko Relkovic, Hannah V Furby, Irina A Guschina, Anna L Hopkins, Jeffrey S Davies, James L Resnick, Anthony R Isles, and Timothy Wells

possible that proportionate hyperphagia may arise from impairment of the anorexic oxytocin circuitry. Although we have yet to quantify oxytocin expression in PWS-IC del mice, a reduction in the population of parvocellular oxytocin neurons has previously