Introduction When Geoffrey Harris wrote his influential monograph on ‘Neural Control of the Pituitary Gland’, it was already apparent that prolactin, or ‘lactogenic hormone’ as he referred to it, might be controlled differently to the other
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Emma Castrique, Marta Fernandez-Fuente, Paul Le Tissier, Andy Herman, and Andy Levy
the physical expansion of the pituitary during pregnancy and lactation ( Gonzalez et al . 1988 , Elster et al . 1991 , Dinc et al . 1998 , Chanson et al . 2001 ). Several morphometric studies have identified the prolactin (PRL) cell population
Dominik Simon Botermann, Nadine Brandes, Anke Frommhold, Ina Heß, Alexander Wolff, Arne Zibat, Heidi Hahn, Rolf Buslei, and Anja Uhmann
/adrenocorticotropic hormone- (Acth), somatotrophs/growth hormone- (Gh), prolactin- (Prl), thyroid-stimulating hormone-, luteinizing hormone-, follicle-stimulating hormone-secreting cells), the anterior lobe (AL) of the pituitary consists of Sox2 + (stem) cells and a meshwork
Shona Wood and Andrew Loudon
-out of the seasonal response is seen in the expression of a seasonal pituitary prolactin rhythm, which is activated by long photoperiods, driving moult cycles in birds and mammals ( Fig. 1 ). In small short-lived mammals such as Siberian hamsters, LD
L A Nolan and A Levy
suckling does not take place, lactotroph mass returns to almost normal within 1–3 weeks, but remains slightly higher after pregnancy than in nulliparous rats, implying that pregnancy-induced changes in the size of the prolactin immunopositive population are
Nadia Schoenmakers, Kyriaki S Alatzoglou, V Krishna Chatterjee, and Mehul T Dattani
αGSU will only be detected in thyrotropes and gonadotropes ( Ericson et al . 1998 , Himes & Raetzman 2009 , Kelberman et al . 2009 ). The expression of GH and Prolactin ( Prl ) by E15.5 is the hallmark of the differentiation of somatotrope and
Koichiro Taguchi, Kazuo Kajita, Yoshihiko Kitada, Masayuki Fuwa, Motochika Asano, Takahide Ikeda, Toshiko Kajita, Tatsuo Ishizuka, Itaru Kojima, and Hiroyuki Morita
, expression levels of members of the prolactin family, prolactin family 2, subfamily c, member 3 ( Prl2c3: Plf ) and prolactin family 2, subfamily c, member 5 ( Prl2c5 ) were elevated only in SPA. On the other hand, microarray revealed that numerous adipocyte
Sian J S Simpson, Lorna I F Smith, Peter M Jones, and James E Bowe
organ, secreting numerous hormonal signals, which influence maternal and foetal physiology ( Jansson 2016 ). The lactogenic hormones, prolactin and placental lactogen, are important pregnancy-associated signals, well-established to act via β
F Wahab, M Shahab, and R Behr
very recent study demonstrated an important role of prolactin in the lactation-induced suppression of KP release and reproduction ( Brown et al . 2014 ). Figure 3 A possible mechanism of lactation-induced suppression of the reproductive axis. Metabolic
Erica Yeo, Patricia L Brubaker, and Deborah M Sloboda
resistance which drives maternal β-cells to synthesize and secrete more insulin. This expansion of insulin-producing β-cells coincides with the onset of PL, PGH and prolactin (PrL) secretion from the placenta. As PL, PGH and PrL induce β-cell proliferation
