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R Prasad, J C Kowalczyk, E Meimaridou, H L Storr, and L A Metherell

Introduction Reactive oxygen species (ROS) are derived from O 2 and comprise molecules with varying oxidant properties. At low concentrations, ROS modulate many cellular processes through redox-dependent signalling, including proliferation

Open access

E Meimaridou, M Goldsworthy, V Chortis, E Fragouli, P A Foster, W Arlt, R Cox, and L A Metherell

receptor on a B6/Balbc mix background . Molecular and Cellular Endocrinology 300 32 – 36 . ( ) 19022343 10.1016/j.mce.2008.10.027 Diemer T Allen JA Hales KH Hales DB 2003 Reactive oxygen

Open access

Alvaro Souto Padron, Ruy Andrade Louzada Neto, Thiago Urgal Pantaleão, Maria Carolina de Souza dos Santos, Renata Lopes Araujo, Bruno Moulin de Andrade, Monique da Silva Leandro, João Pedro Saar Werneck de Castro, Andrea Claudia Freitas Ferreira, and Denise Pires de Carvalho

Caillou B Talbot M Ameziane-El-Hassani R Lacroix L Lagent-Chevallier O Al Ghuzlan A Roos D Bidart JM Virion A 2010 Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid

Open access

Helen L Jeanes, Caroline Tabor, Darcey Black, Antwan Ederveen, and Gillian A Gray

Pedram A Razandi M Levin ER 2006 Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 kinase isoforms . Journal of Biological Chemistry 281 6760 – 6767 . Lesnefsky EJ Moghaddas

Open access

Joachim M Weitzel, Torsten Viergutz, Dirk Albrecht, Rupert Bruckmaier, Marion Schmicke, Armin Tuchscherer, Franziska Koch, and Björn Kuhla

these defense enzymes seems to be a mechanism to allow for accumulating levels of peroxides and other reactive oxygen species, which in turn may activate transcription factors such as heat shock factor 1 ( HSF1 ) or hypoxia-inducible factor 1 ( HIF-1

Open access

Bernadette M Trojanowski, Heba H Salem, Heike Neubauer, Eric Simon, Martin Wagner, Rajkumar Dorajoo, Bernhard O Boehm, Leticia Labriola, Thomas Wirth, and Bernd Baumann

-induced precancerous lesions in the pancreas . Oncogene 2690 – 2695 . ( ) Morgan MJ Liu ZG 2011 Crosstalk of reactive oxygen species and NF-kappaB signaling . Cell Research 103 – 115 . (

Open access

Xuefeng Yang, Shuang Mei, Haihua Gu, Huailan Guo, Longying Zha, Junwei Cai, Xuefeng Li, Zhenqi Liu, and Wenhong Cao

Healthcare. Measurement of ROS production from cultured cells Intracellular reactive oxygen species (ROS) was detected using fluorescent DCF-DA as described previously ( Palmer et al . 1977 , D'Alessandro et al . 2011 ). In brief, the non-fluorescent dye

Open access

Valentina Pampanini, Daniela Germani, Antonella Puglianiello, Jan-Bernd Stukenborg, Ahmed Reda, Iuliia Savchuk, Kristín Rós Kjartansdóttir, Stefano Cianfarani, and Olle Söder

the production of reactive oxygen species (ROS). Those molecules can directly bind to specific sites on DNA and cause genetic and epigenetic modifications, e.g. by interfering with DNA methylation and histone configuration ( Thompson & Al-Hasan 2012

Open access

Colin P Sibley

latter symptoms, there have been virtually no reports of models with defective invasion. This is because of the major differences in placentation between species, with few showing the deep invasion by EVT found in women. Even when there are maternal