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-dark cycle (light on 07:00–19:00 h) with ad libitum or time-restricted feeding access to standard powder chow (10 kcal% fat, produced by Research Diets, Inc.: open source diet code D12450B) and water. All the experiments were performed in accordance with
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Tokyo Adachi Hospital, Adachi, Tokyo, Japan
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(+/+) mice and the APN (−/−) mice are similar to this behavioral pattern, that is, the amount of food intake by the APN (+/+) mice decreased between CT14 and CT16, showing a bimodal pattern, whereas the APN (−/−) mice were still feeding at that time period
Gulbali Institute, Charles Sturt University, Wagga Wagga, NSW, Australia
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Gulbali Institute, Charles Sturt University, Wagga Wagga, NSW, Australia
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Gulbali Institute, Charles Sturt University, Wagga Wagga, NSW, Australia
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with an LH surge were excluded from analysis. Analysis was restricted to the period during which sampling occurred every 10 min. Inter-pulse interval (IPI) was calculated as the interval in time between the start of two adjacent pulses. A mixed
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responses such as pigmentation ( Lerner & McGuire 1961 ), sexual behavior ( Bertolini et al . 1968 ), thermoregulation, and inflammatory responses, but also feeding ( Vergoni et al . 1986 ) and control of body weight ( Fan et al . 1997 , MacNeil et al
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KP containing cells in the brain center for feeding and reproduction control Besides many other functions, the hypothalamus is the brain center for the regulation of feeding and reproduction ( Kennedy & Mitra 1963 b , Wynne et al . 2005 ). It serves
Department of Internal Medicine IV, Division of Diabetology, Endocrinology and Nephrology, Eberhard-Karls University of Tübingen, Tübingen, Germany
Institute for Diabetes Research and Metabolic Diseases, Helmholtz Center Munich, Eberhard-Karls University of Tübingen, Tübingen, Germany
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Department of Internal Medicine IV, Division of Diabetology, Endocrinology and Nephrology, Eberhard-Karls University of Tübingen, Tübingen, Germany
Institute for Diabetes Research and Metabolic Diseases, Helmholtz Center Munich, Eberhard-Karls University of Tübingen, Tübingen, Germany
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Beyl R Early KS Cefalu WT Ravussin E & Peterson CM 2018 Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes . Cell Metabolism 27 1212 – 1221.e3
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development. However, despite cell death, Slc2a3 −/− embryos implanted but were lost at embryonic day 8.5 ( Ganguly et al . 2007 ). Here, we describe the exact time point of embryonic lethality, and identify the defect responsible for death of post
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) were maintained at 28°C on a 14/10 h light/dark cycle in a re-circulating system with reverse osmosis dosed-salt water (pH 7.6 and conductivity of 800 µs). Fish were fed three times a day, once with live brine shrimp and twice with dry feed (Gemma
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Early Life Nutrition Research Unit, Respiratory Biomedical Research Unit, Department of Animal Sciences, Division of Human Development, Academic Child Health
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Early Life Nutrition Research Unit, Respiratory Biomedical Research Unit, Department of Animal Sciences, Division of Human Development, Academic Child Health
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calculated using the 2 −Δ C t method ( Livak & Schmittgen 2001 ). Gene expression data are normalised to the 1-day-old group born to multiparous mothers and are presented as a fold change. Quantitative real-time PCR analysis The relative abundance of GR, HSD
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EPSRC Centre for Predictive Modelling in Healthcare, University of Exeter, Exeter, UK
Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, UK
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the impact of neuronal activity within a network on other functions. This methodology has been successfully used to study arcuate nucleus and amygdala control of feeding behaviour in freely moving mice ( Betley et al. 2015 , Jennings et al. 2015