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State Key Laboratory of Marine Pollution (SKLMP) at City University of Hong Kong, Hong Kong SAR, People’s Republic of China
Department of Materials Science and Engineering, College of Science and Engineering, City University of Hong Kong, Hong Kong SAR, People’s Republic of China
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sex (usually male) and sexual differences in regeneration have never been investigated. In the present study, we examine, for the first time, sexual dimorphism of zebrafish heart regeneration and factors that influence the rate of cardiac regeneration
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assessment of isolated populations or deduced from cohort differences due to sex or suppression of endogenous hormones. It is well known that sexual dimorphism in immune responses affects the prevalence and severity of a range of inflammatory conditions, but
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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-temporal expression of ERα and ERβ was reported to contribute to organize sex differences that are not associated with reproduction, such as the stress response and cognition ( Mogi et al. 2015 ). It is conceivable that the sexual dimorphism observed in
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either global P -values for genotype adjusted for multiple correction testing, or (in the cases of sexual dimorphism) the P -value is the impact of genotype for that sex. Animal husbandry The care and use of all animals were carried out in
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, although the ultimate reason for the observed sexual dimorphism remains obscure. 11β-HSD1/H6PDH HETs and double HETs have a urinary 11-DHC profile that is comparable to that of WT animals ( Fig. 2 ). Loss of one 11β-HSD1 and/or one H6PDH allele therefore
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striking sexual dimorphism . Journal of Physiology 549 835 – 843 . Oishi Y Okuda M Takahashi H Fujii T Morii S 1993 Cellular proliferation in the anterior pituitary gland of normal adult rats: influences of sex, estrous cycle, and
Royal (Dick) School of Veterinary Studies, MRC Human Reproductive Sciences Unit, MRC/UCT, The Roslin Institute, University of Edinburgh, Roslin, Midlothian, Edinburgh EH25 9PS, UK
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Royal (Dick) School of Veterinary Studies, MRC Human Reproductive Sciences Unit, MRC/UCT, The Roslin Institute, University of Edinburgh, Roslin, Midlothian, Edinburgh EH25 9PS, UK
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due to the age of animals used in different studies. The sexual dimorphism in cGnRH-R-III expression, where levels of mRNA are higher in juvenile males compared with juvenile females, is consistent with the LH response to photo-stimulation seen in
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murine embryonic and postnatal mechanisms of IGFBP-4 without specifically looking at sexual dimorphism ( Ning et al . 2006 , 2008 ). In contrast, we examined pubertal and adult skeletal maintenance in C57BL/6J mice by phenotyping mice with a germline
Department of Biosciences, Nottingham Trent University, Nottingham, UK
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NEXUS, Discovery Way, University of Leeds, Leeds, UK
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Department of Biosciences, Nottingham Trent University, Nottingham, UK
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in male mice. As such, we can discount the possibility of sexual dimorphism with respect to our findings. Indeed, there is evidence of sexually dimorphic expression of hepatic 11β-HSD1 in rats, underpinned by sex-specific changes in growth hormone
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.3791/2429 ) Kotani K Tokunaga K Fujioka S Kobatake T Keno Y Yoshida S Shimomura I Tarui S Matsuzawa Y 1994 Sexual dimorphism of age-related-changes in whole-body fat distribution in the obese . International Journal of Obesity and Related Metabolic Disorders