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Sami Ayari, Eva Gil-Iturbe, Léa le Gléau, Céline Osinski, Nathalie Kapel, Hedi Antoine Soula, Armelle Leturque, Fabrizio Andreelli, Karine Clément, Patricia Serradas, and Agnès Ribeiro

transcriptional activity of murine hepatocyte nuclear factor 4gamma . Biochimica et Biophysica Acta 1490 21 – 32 . ( ) Torres-Padilla ME Fougere-Deschatrette C Weiss MC 2001 Expression of HNF4alpha isoforms in

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Haifan Zhang, Tim McElrath, Wei Tong, and Jeffrey W Pollard

the ER in both these tissues ( Jordan & Morrow 1999 ). The ER has two transcriptional activation domains, AF-1 and AF-2. AF-1 activity is stimulated by tamoxifen binding but AF-2 is inhibited ( Smith et al. 1997 , McDonnell 1999 ) while E 2

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Palaniappan Murugesan, Muthusamy Balaganesh, Karundevi Balasubramanian, and Jagadeesan Arunakaran

) with high affinity ( Safe 1995 ). The AhR is a ligand-activated transcription factor that, upon binding of PCBs or dioxin, translocates to the nucleus where it heterodimerizes with the aryl hydrocarbon nuclear translocator. This complex then binds to

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Mi-Hyun Kim, Jae-Hwan Jee, Sunyoung Park, Myung-Shik Lee, Kwang-Won Kim, and Moon-Kyu Lee

combination of β-catenin with TCF7L2 stimulates transcriptional activity of Glu , a precursor of GLP1, and increases GLP1 production. SGLT1, sodium/glucose cotransporter; CAMK2, calcium-calmodulin dependent kinase 2; CREB, cAMP response element binding

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Fu-Qing Yu, Chun-Sheng Han, Wei Yang, Xuan Jin, Zhao-Yuan Hu, and Yi-Xun Liu

cholesterol from mitochondrial outer membrane to inner membrane, where cytochrome P450 side-chain cleavage enzyme (P450 scc) resides ( Christenson & Strauss 2000 , Stocco 2000 ). StAR expression is regulated by several transcription factors such as DAX-1

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A K Katakam, G Chipitsyna, Q Gong, A R Vancha, J Gabbeta, and H A Arafat

. Oligo (dT) 15 (Promega)-primed cDNA was synthesized from 3.5 g total RNA using Moloney murine leukemia virus RT (Gibco BRL) at 37 °C for 60 min. Samples were incubated at 90 °C for 5 min to terminate the reverse transcription reaction. The cDNA mixtures

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Vinay Shukla, Jyoti Bala Kaushal, Pushplata Sankhwar, Murli Manohar, and Anila Dwivedi

24 h, the cells were lysed with lysis buffer. Luciferase activity was measured using Dual Luciferase Assay System (Promega) according to the manufacturer’s protocol to detect the transcriptional activity of the transfected promoter. The firefly

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Shona Wood and Andrew Loudon

. 2008 ). This SCN read-out of the photoperiod signal has all of the characteristics of an internal co-incidence timer, and is also reflected in changes in the patterns of SCN electrical activity ( Brown & Piggins 2009 ). The current dogma is that the

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Pulak R Manna, Youngah Jo, and Douglas M Stocco

regulation of steroid synthesis has been documented with both basic and clinical studies ( Clark et al. 1994 , Lin et al. 1995 , Caron et al. 1997 , Hasegawa et al. 2000 ). Transcriptional or translational inhibition of StAR expression results in a

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J E Sánchez-Criado, J Martín de las Mulas, C Bellido, V M Navarro, R Aguilar, J C Garrido-Gracia, M M Malagón, M Tena-Sempere, and A Blanco

Neuroendocrinology 15 984 –990. Hall JM & McDonnell DP 1999 The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of cellular response to estrogen and