Search Results
Manuela Elsen
Manuela Elsen
Paul-Langerhans-Group for Integrative Physiology, German Diabetes Center, Auf'm Hennekamp 65, 40225 Düsseldorf, Germany
Search for other papers by Manuela Elsen in
Google Scholar
PubMed
Search for other papers by Manuela Elsen in
Google Scholar
PubMed
Silja Raschke
Silja Raschke
Paul-Langerhans-Group for Integrative Physiology, German Diabetes Center, Auf'm Hennekamp 65, 40225 Düsseldorf, Germany
Search for other papers by Silja Raschke in
Google Scholar
PubMed
Search for other papers by Silja Raschke in
Google Scholar
PubMed
Jürgen Eckel
Jürgen Eckel
Paul-Langerhans-Group for Integrative Physiology, German Diabetes Center, Auf'm Hennekamp 65, 40225 Düsseldorf, Germany
Search for other papers by Jürgen Eckel in
Google Scholar
PubMed
Search for other papers by Jürgen Eckel in
Google Scholar
PubMed
-induced insulin resistance ( Boström et al . 2012 a ). These results suggested a potential protective role of irisin in the development of type 2 diabetes, one of the major obesity-associated metabolic diseases. In order to investigate the relevance of irisin in
Bernard Khoo
Bernard Khoo
Endocrinology, Division of Medicine, University College London, Royal Free Campus, London, UK
Search for other papers by Bernard Khoo in
Google Scholar
PubMed
Search for other papers by Bernard Khoo in
Google Scholar
PubMed
Tricia Mei-Mei Tan
Tricia Mei-Mei Tan
Department of Digestion, Metabolism and Reproduction, Imperial College London, Hammersmith Campus, London, UK
Search for other papers by Tricia Mei-Mei Tan in
Google Scholar
PubMed
Search for other papers by Tricia Mei-Mei Tan in
Google Scholar
PubMed
, type 2 diabetes (T2D), hypertension, hyperlipidaemia, obstructive sleep apnoea, subfertility, cancers (breast, ovary, prostate, liver, endometrium and colon) and fatty liver disease/steatohepatitis leading to cirrhosis and liver failure. Key drivers of
Yolanda Diz-Chaves
Yolanda Diz-Chaves
Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Yolanda Diz-Chaves in
Google Scholar
PubMed
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Yolanda Diz-Chaves in
Google Scholar
PubMed
Manuel Gil-Lozano
Manuel Gil-Lozano
Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Manuel Gil-Lozano in
Google Scholar
PubMed
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Manuel Gil-Lozano in
Google Scholar
PubMed
Laura Toba
Laura Toba
Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Laura Toba in
Google Scholar
PubMed
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Laura Toba in
Google Scholar
PubMed
Juan Fandiño
Juan Fandiño
Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Juan Fandiño in
Google Scholar
PubMed
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Juan Fandiño in
Google Scholar
PubMed
Hugo Ogando
Hugo Ogando
Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Hugo Ogando in
Google Scholar
PubMed
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Hugo Ogando in
Google Scholar
PubMed
Lucas C González-Matías
Lucas C González-Matías
Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Lucas C González-Matías in
Google Scholar
PubMed
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Lucas C González-Matías in
Google Scholar
PubMed
Federico Mallo
Federico Mallo
Laboratory of Endocrinology, Center for Biomedical Research – CINBIO, University of Vigo, Vigo, Spain
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Federico Mallo in
Google Scholar
PubMed
Instituto de Investigación Sanitaria Galicia Sur – IISGS, Vigo, Spain
Search for other papers by Federico Mallo in
Google Scholar
PubMed
nervous system (SNS) activation, favours the accumulation of visceral fat and contributes to the clinical presentation of visceral obesity, type 2 diabetes mellitus (DM2) and related cardiometabolic complications. In addition, both circulating and local
Mohammed Bensellam
Mohammed Bensellam
Garvan Institute of Medical Research, Sydney, New South Wales, Australia
Université Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Pôle d’Endocrinologie, Diabète et Nutrition, Brussels, Belgium
Search for other papers by Mohammed Bensellam in
Google Scholar
PubMed
Université Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Pôle d’Endocrinologie, Diabète et Nutrition, Brussels, Belgium
Search for other papers by Mohammed Bensellam in
Google Scholar
PubMed
Jean-Christophe Jonas
Jean-Christophe Jonas
Université Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Pôle d’Endocrinologie, Diabète et Nutrition, Brussels, Belgium
Search for other papers by Jean-Christophe Jonas in
Google Scholar
PubMed
Search for other papers by Jean-Christophe Jonas in
Google Scholar
PubMed
D Ross Laybutt
D Ross Laybutt
Garvan Institute of Medical Research, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Sydney, Sydney, New South Wales, Australia
Search for other papers by D Ross Laybutt in
Google Scholar
PubMed
St Vincent’s Clinical School, UNSW Sydney, Sydney, New South Wales, Australia
Search for other papers by D Ross Laybutt in
Google Scholar
PubMed
animal and human studies suggest that mature β-cells could regress backwards to a precursor-like stage and/or transdifferentiate into other islet cells in type 2 diabetes. Interestingly, cellular differentiation is not unidirectional. Indeed
Prabhakara R Nagareddy
Prabhakara R Nagareddy
Department of Nutrition Sciences, University of Alabama, Birmingham, UK
Search for other papers by Prabhakara R Nagareddy in
Google Scholar
PubMed
Search for other papers by Prabhakara R Nagareddy in
Google Scholar
PubMed
Sunil K Noothi
Sunil K Noothi
Department of Nutrition Sciences, University of Alabama, Birmingham, UK
Search for other papers by Sunil K Noothi in
Google Scholar
PubMed
Search for other papers by Sunil K Noothi in
Google Scholar
PubMed
Michelle C Flynn
Michelle C Flynn
Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia
Department of Immunology, Monash University, Melbourne, Australia
Search for other papers by Michelle C Flynn in
Google Scholar
PubMed
Department of Immunology, Monash University, Melbourne, Australia
Search for other papers by Michelle C Flynn in
Google Scholar
PubMed
Andrew J Murphy
Andrew J Murphy
Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia
Department of Immunology, Monash University, Melbourne, Australia
Search for other papers by Andrew J Murphy in
Google Scholar
PubMed
Department of Immunology, Monash University, Melbourne, Australia
Search for other papers by Andrew J Murphy in
Google Scholar
PubMed
such as diabetes and metabolic syndrome to promote an exacerbated myelopoietic phenotype. The mechanisms of each of these risk factors in relation to myeloid-driven CAD are summarized in Fig. 1 (modified from Murphy & Tall 2016 ) and detailed below
Weiwei Xu
Weiwei Xu
Section of Endocrinology and Metabolism, Department of Medicine, Diabetes Discovery Research and Gender Medicine Laboratory, Tulane University Health Sciences Center, School of Medicine, and Southeast Louisiana Veterans Healthcare System Medical Center, New Orleans, Louisiana, USA
Search for other papers by Weiwei Xu in
Google Scholar
PubMed
Search for other papers by Weiwei Xu in
Google Scholar
PubMed
Jamie Morford
Jamie Morford
Section of Endocrinology and Metabolism, Department of Medicine, Diabetes Discovery Research and Gender Medicine Laboratory, Tulane University Health Sciences Center, School of Medicine, and Southeast Louisiana Veterans Healthcare System Medical Center, New Orleans, Louisiana, USA
Search for other papers by Jamie Morford in
Google Scholar
PubMed
Search for other papers by Jamie Morford in
Google Scholar
PubMed
Franck Mauvais-Jarvis
Franck Mauvais-Jarvis
Section of Endocrinology and Metabolism, Department of Medicine, Diabetes Discovery Research and Gender Medicine Laboratory, Tulane University Health Sciences Center, School of Medicine, and Southeast Louisiana Veterans Healthcare System Medical Center, New Orleans, Louisiana, USA
Search for other papers by Franck Mauvais-Jarvis in
Google Scholar
PubMed
Search for other papers by Franck Mauvais-Jarvis in
Google Scholar
PubMed
particularly surprising, as observational studies have implicated low testosterone levels in both the development of insulin resistance and the pathogenesis of hyperglycemia and diabetes in men, and hyperglycemia requires β cell dysfunction to develop. In the
Andrew W Norris
Andrew W Norris
Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA
Search for other papers by Andrew W Norris in
Google Scholar
PubMed
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA
Search for other papers by Andrew W Norris in
Google Scholar
PubMed
Katie Larson Ode
Katie Larson Ode
Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA
Search for other papers by Katie Larson Ode in
Google Scholar
PubMed
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA
Search for other papers by Katie Larson Ode in
Google Scholar
PubMed
Lina Merjaneh
Lina Merjaneh
Division of Endocrinology & Diabetes, Seattle Children’s Hospital, Seattle, Washington, USA
Search for other papers by Lina Merjaneh in
Google Scholar
PubMed
Search for other papers by Lina Merjaneh in
Google Scholar
PubMed
Srinath Sanda
Srinath Sanda
Department of Pediatrics, University of California San Francisco, San Francisco, California, USA
Diabetes Center, University of California San Francisco, San Francisco, California, USA
Search for other papers by Srinath Sanda in
Google Scholar
PubMed
Diabetes Center, University of California San Francisco, San Francisco, California, USA
Search for other papers by Srinath Sanda in
Google Scholar
PubMed
Yaling Yi
Yaling Yi
Department of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA
Search for other papers by Yaling Yi in
Google Scholar
PubMed
Search for other papers by Yaling Yi in
Google Scholar
PubMed
Xingshen Sun
Xingshen Sun
Department of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA
Search for other papers by Xingshen Sun in
Google Scholar
PubMed
Search for other papers by Xingshen Sun in
Google Scholar
PubMed
John F Engelhardt
John F Engelhardt
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA
Department of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA
Search for other papers by John F Engelhardt in
Google Scholar
PubMed
Department of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA
Search for other papers by John F Engelhardt in
Google Scholar
PubMed
Rebecca L Hull
Rebecca L Hull
Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA
Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, Washington, USA
Search for other papers by Rebecca L Hull in
Google Scholar
PubMed
Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, Washington, USA
Search for other papers by Rebecca L Hull in
Google Scholar
PubMed
Example Disease Pancreatic insufficiency risk (Ahmed et al . 2003) Diabetes risk (Adler et al . 2008) I Failed synthesis G542X Severe High High II Failed protein processing F508del Severe High High III
Louis Potier
Louis Potier
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Louis Potier in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Louis Potier in
Google Scholar
PubMed
Ludovic Waeckel
Ludovic Waeckel
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Ludovic Waeckel in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Ludovic Waeckel in
Google Scholar
PubMed
Fréderic Fumeron
Fréderic Fumeron
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Fréderic Fumeron in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Fréderic Fumeron in
Google Scholar
PubMed
Sophie Bodin
Sophie Bodin
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Sophie Bodin in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Sophie Bodin in
Google Scholar
PubMed
Marinos Fysekidis
Marinos Fysekidis
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Marinos Fysekidis in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Marinos Fysekidis in
Google Scholar
PubMed
Catherine Chollet
Catherine Chollet
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Catherine Chollet in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Catherine Chollet in
Google Scholar
PubMed
Naima Bellili
Naima Bellili
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Naima Bellili in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Naima Bellili in
Google Scholar
PubMed
Fabrice Bonnet
Fabrice Bonnet
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Fabrice Bonnet in
Google Scholar
PubMed
Search for other papers by Fabrice Bonnet in
Google Scholar
PubMed
Gaëlle Gusto
Gaëlle Gusto
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Gaëlle Gusto in
Google Scholar
PubMed
Search for other papers by Gaëlle Gusto in
Google Scholar
PubMed
Gilberto Velho
Gilberto Velho
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Gilberto Velho in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Gilberto Velho in
Google Scholar
PubMed
Michel Marre
Michel Marre
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Michel Marre in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Michel Marre in
Google Scholar
PubMed
François Alhenc-Gelas
François Alhenc-Gelas
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by François Alhenc-Gelas in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by François Alhenc-Gelas in
Google Scholar
PubMed
Ronan Roussel
Ronan Roussel
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Ronan Roussel in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Ronan Roussel in
Google Scholar
PubMed
Nadine Bouby
Nadine Bouby
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Nadine Bouby in
Google Scholar
PubMed
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
INSERM U1138, University Paris Descartes, University Pierre and Marie Curie, Diabetology, INSERM U695, Paris Diderot University, Department of Endocrinology, Institut inter Régional Pour la Santé, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France
Search for other papers by Nadine Bouby in
Google Scholar
PubMed
the DESIR study group
the DESIR study group
Search for other papers by the DESIR study group in
Google Scholar
PubMed
Search for other papers by the DESIR study group in
Google Scholar
PubMed
obesity-related disorders have provided encouraging but still limited results ( Satterfield et al . 2003 , Laatikainen et al . 2007 ). The pathogenesis of insulin resistance and diabetes in obesity is complex and still incompletely understood. Besides
Alex Rafacho
Alex Rafacho
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
Search for other papers by Alex Rafacho in
Google Scholar
PubMed
Search for other papers by Alex Rafacho in
Google Scholar
PubMed
Henrik Ortsäter
Henrik Ortsäter
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
Search for other papers by Henrik Ortsäter in
Google Scholar
PubMed
Search for other papers by Henrik Ortsäter in
Google Scholar
PubMed
Angel Nadal
Angel Nadal
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
Search for other papers by Angel Nadal in
Google Scholar
PubMed
Search for other papers by Angel Nadal in
Google Scholar
PubMed
Ivan Quesada
Ivan Quesada
Department of Physiological Sciences, Department of Clinical Science and Education, Institute of Bioengineering and the Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Center of Biological Sciences, Federal University of Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
Search for other papers by Ivan Quesada in
Google Scholar
PubMed
Search for other papers by Ivan Quesada in
Google Scholar
PubMed
effects, including peripheral insulin resistance (IR) and glucose intolerance as well as overt hyperglycaemia and diabetes. These side effects are observed particularly in susceptible individuals such as pregnant women, obese subjects, IR individuals or
Noèlia Téllez
Noèlia Téllez
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
Search for other papers by Noèlia Téllez in
Google Scholar
PubMed
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
Search for other papers by Noèlia Téllez in
Google Scholar
PubMed
Eduard Montanya
Eduard Montanya
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
Search for other papers by Eduard Montanya in
Google Scholar
PubMed
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
CIBER of Diabetes and Metabolic Diseases, Bellvitge Biomedical Research Institute, Endocrine Unit, Department of Clinical Sciences, CIBERDEM, Barcelona, Spain
Search for other papers by Eduard Montanya in
Google Scholar
PubMed
Introduction β-cell mass reduction is a central event in the development of types 1 and 2 diabetes, and β-cell regeneration is a potentially curative treatment for the disease. Strategies aiming to regenerate β-cell mass include stimulation of
