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Shannon M Bailey Division of Molecular and Cellular Pathology, Division of Cardiovascular Diseases, Department of Pathology

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Uduak S Udoh Division of Molecular and Cellular Pathology, Division of Cardiovascular Diseases, Department of Pathology

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Martin E Young Division of Molecular and Cellular Pathology, Division of Cardiovascular Diseases, Department of Pathology

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) showed that insulin secretion from isolated pancreatic rat islets display a circadian rhythm that originates within the islet. Further, plasma insulin concentrations in rats exhibit daily oscillations with distinct increments at every meal ( Kalsbeek

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-14-0200
Volume/Issue:
Volume 222: Issue 2
Free access
Nava Chapnik
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Gili Solomon
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Yoni Genzer
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Ruth Miskin Robert H. Smith Faculty of Agriculture, Department of Biological Chemistry, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University of Jerusalem, Rehovot 76100, Israel

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Arieh Gertler
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Oren Froy
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neuropeptides in the brain ( Froy et al . 2011 ). αMUPA mice also show pronounced circadian rhythms ( Froy et al . 2006 ) and altered locomotor activity compared with FVB/N mice ( Gutman et al . 2011 ). αMUPA mice that spontaneously consume less food per day

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0033
Volume/Issue:
Volume 217: Issue 3
Free access
Sarika Paul Centre for Biological Timing, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK

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Timothy M Brown Centre for Biological Timing, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK

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function ( Takahashi 2015 ). In the case of the SCN, these clock controlled genes include membrane ion channels, thereby generating pronounced circadian rhythms in the excitability and spontaneous electrical activity of SCN neurons ( Belle & Allen 2018

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0302
Volume/Issue:
Volume 243: Issue 1
Free access
Francesca Spiga Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK

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Jamie J Walker Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK

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Rita Gupta Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK

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John R Terry Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK

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Stafford L Lightman Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, College of Engineering, Wellcome Trust Centre for Biomedical Modelling and Analysis, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK

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glucocorticoid pulsatility The circadian rhythm of the HPA axis is under the control of the suprachiasmatic nucleus (SCN), which directly regulates the pattern of CRH and AVP release from the PVN, and in addition modulates the responsiveness of the adrenal gland

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-15-0132
Volume/Issue:
Volume 226: Issue 2
Free access
Dario R Lemos Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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Jodi L Downs Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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Martin N Raitiere Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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Henryk F Urbanski Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of
Division of Neuroscience, Physiology and Pharmacology, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA Departments of

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Introduction In mammals, many aspects of physiology and behavior are temporally regulated, showing circadian as well as circannual rhythms. Whereas, circadian rhythms reflect the daily organization of body functions, circannual rhythms represent an

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0437
Volume/Issue:
Volume 201: Issue 2
Free access
Pei-Jian He Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences, Graduate School of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan
Molecular Medicine Research Labs, Drug Discovery Research, Astellas Pharma Inc., Miyukigaoka 21, Tsukuba-shi, Ibaraki 305-8585, Japan

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Masami Hirata Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences, Graduate School of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan
Molecular Medicine Research Labs, Drug Discovery Research, Astellas Pharma Inc., Miyukigaoka 21, Tsukuba-shi, Ibaraki 305-8585, Japan

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Nobuhiko Yamauchi Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences, Graduate School of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan
Molecular Medicine Research Labs, Drug Discovery Research, Astellas Pharma Inc., Miyukigaoka 21, Tsukuba-shi, Ibaraki 305-8585, Japan

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Seiichi Hashimoto Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences, Graduate School of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan
Molecular Medicine Research Labs, Drug Discovery Research, Astellas Pharma Inc., Miyukigaoka 21, Tsukuba-shi, Ibaraki 305-8585, Japan

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Masa-aki Hattori Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences, Graduate School of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan
Molecular Medicine Research Labs, Drug Discovery Research, Astellas Pharma Inc., Miyukigaoka 21, Tsukuba-shi, Ibaraki 305-8585, Japan

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, which is critical for successful pregnancy in rodents ( Gu et al. 1994 ). The present finding predicts that, in vivo , the circadian rhythms in the endometrial stroma may be impaired during decidualization. In vivo , cellular differentiation

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0044
Volume/Issue:
Volume 193: Issue 3
Free access
Sophie M T Wehrens Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK

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Shelagh M Hampton Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK

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Rebecca E Finn Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK

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Debra J Skene Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK

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given are those obtained during the week prior to the study (see Materials and Methods). Prior to the laboratory session In order to maintain or establish regular circadian rhythms (i.e. for the shift workers to be adapted for the laboratory study) and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0077
Volume/Issue:
Volume 206: Issue 2
Free access
Michaela D Wharfe School of Anatomy, Metabolomics Australia, Physiology and Human Biology, The University of Western Australia, M309, Perth 6009, Australia

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Peter J Mark School of Anatomy, Metabolomics Australia, Physiology and Human Biology, The University of Western Australia, M309, Perth 6009, Australia

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Caitlin S Wyrwoll School of Anatomy, Metabolomics Australia, Physiology and Human Biology, The University of Western Australia, M309, Perth 6009, Australia

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Jeremy T Smith School of Anatomy, Metabolomics Australia, Physiology and Human Biology, The University of Western Australia, M309, Perth 6009, Australia

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Cassandra Yap School of Anatomy, Metabolomics Australia, Physiology and Human Biology, The University of Western Australia, M309, Perth 6009, Australia

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Michael W Clarke School of Anatomy, Metabolomics Australia, Physiology and Human Biology, The University of Western Australia, M309, Perth 6009, Australia

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Brendan J Waddell School of Anatomy, Metabolomics Australia, Physiology and Human Biology, The University of Western Australia, M309, Perth 6009, Australia

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, referred to as ‘peripheral clocks’. The circadian rhythm of circulating glucocorticoids (generated via the HPA axis) provides a key coordination link between the central SCN clock and these peripheral clocks ( Hastings et al . 2007 ), and as such plays a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0405
Volume/Issue:
Volume 228: Issue 3
Free access
Lucia Gajdosechova Institute of Experimental Endocrinology, Unit of Physiology, Institute of Organic Chemistry and Biochemistry, Chair of Pharmacology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia

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Katarina Krskova Institute of Experimental Endocrinology, Unit of Physiology, Institute of Organic Chemistry and Biochemistry, Chair of Pharmacology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia

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Ana Belen Segarra Institute of Experimental Endocrinology, Unit of Physiology, Institute of Organic Chemistry and Biochemistry, Chair of Pharmacology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia

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Andrea Spolcova Institute of Experimental Endocrinology, Unit of Physiology, Institute of Organic Chemistry and Biochemistry, Chair of Pharmacology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia

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Maciej Suski Institute of Experimental Endocrinology, Unit of Physiology, Institute of Organic Chemistry and Biochemistry, Chair of Pharmacology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia

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Rafal Olszanecki Institute of Experimental Endocrinology, Unit of Physiology, Institute of Organic Chemistry and Biochemistry, Chair of Pharmacology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia

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Stefan Zorad Institute of Experimental Endocrinology, Unit of Physiology, Institute of Organic Chemistry and Biochemistry, Chair of Pharmacology, Slovak Academy of Sciences, Vlarska 3, 83306 Bratislava, Slovakia

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oxytocin receptors on isolated rat fat cells . European Journal of Biochemistry 56 295 – 303 . ( doi:10.1111/j.1432-1033.1975.tb02233.x ) Bray MS Young ME 2007 Circadian rhythms in the development of obesity: potential role for the circadian

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0417
Volume/Issue:
Volume 220: Issue 3
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Andreas Nygaard Madsen
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Gitte Hansen
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Sarah Juel Paulsen
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Kirsten Lykkegaard
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Mads Tang-Christensen
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Harald S Hansen Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark

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Barry E Levin Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark
Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark

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Philip Just Larsen
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Lotte Bjerre Knudsen Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark

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Keld Fosgerau
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Niels Vrang
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was measured in duplicate at all time points using a commercially available insulin ELISA assay (Diamyd Diagnostics, Stockholm, Sweden). Circadian rhythm hormone profile Measurements of the circadian rhythms of leptin and insulin were performed in rats

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0004
Volume/Issue:
Volume 206: Issue 3
Free access