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Marumi Osuna Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan

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Yokiko Sonobe Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan

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Eisuke Itakura Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan

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Sukumar Devnath Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan

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Takako Kato Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan

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Yukio Kato Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan

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Kinji Inoue Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan
Graduate School of Science and Engineering, Division of Life Science, Department of Physiology and Cell Biology, School of Agriculture and Rural Development, Department of Life Science, Institute of Reproduction and Endocrinology, Research Management Bureau, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan

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Introduction Pituitary folliculostellate (FS) cells are stellate and S100B protein-positive cells that surround neighboring endocrine cells by their long cytoplasmic processes, which are considered to act as a sustentacular cell in the pituitary

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M-O Faure UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Physiologie de la Reproduction et des Comportements, 37380 Nouzilly, France
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK

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L Nicol UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Physiologie de la Reproduction et des Comportements, 37380 Nouzilly, France
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK

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S Fabre UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Physiologie de la Reproduction et des Comportements, 37380 Nouzilly, France
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK

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J Fontaine UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Physiologie de la Reproduction et des Comportements, 37380 Nouzilly, France
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK

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N Mohoric UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Physiologie de la Reproduction et des Comportements, 37380 Nouzilly, France
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK

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A McNeilly UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Physiologie de la Reproduction et des Comportements, 37380 Nouzilly, France
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK

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C Taragnat UMR 6175 INRA-CNRS-Université de TOURS-Haras Nationaux, Physiologie de la Reproduction et des Comportements, 37380 Nouzilly, France
Medical Research Council, Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor’s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK

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Introduction In females the gonadotropins FSH and LH produced by pituitary gonadotropes are required for terminal follicular growth and regulation of ovulation number ( McNeilly et al. 1992 ). The patterns of the synthesis and

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Chiara Onofri Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Marily Theodoropoulou Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Marco Losa Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Eberhard Uhl Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Manfred Lange Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Eduardo Arzt Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Günter K Stalla Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Ulrich Renner Max-Planck-Institute of Psychiatry, Neuroendocrinology Group, Kraepelinstr. 10, D-80804 Munich, Germany
Istituto San Raffaele, Neurosurgical Department, Milano, Italy
Ludwig-Maximilians University, Neurosurgical Department, Munich, Germany
Klinikum Villingen-Schwenningen, Neurosurgical Department, Villingen-Schwenningen, Germany
Laboratorio de Fisiología y Biología Molecular, Departamento Ciencias Biológicas, FCEN-Universidad de Buenos Aires and CONICET, Buenos Aires, Argentina

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Introduction Angiogenesis, the formation of new blood vessels from pre-existing ones, is known to be a fundamental process in the expansion of solid tumours ( Carmeliet 2003 , Ferrara 2004 ) and is also essential for pituitary

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Maria J Chen Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, U-3125 Storrs, Connecticut 06269, USA

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Pinwen Peter Chiou Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, U-3125 Storrs, Connecticut 06269, USA

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Yu-Hsian Liao Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, U-3125 Storrs, Connecticut 06269, USA

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Chun-Mean Lin Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, U-3125 Storrs, Connecticut 06269, USA

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Thomas T Chen Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, U-3125 Storrs, Connecticut 06269, USA

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Introduction Development of in vitro systems is crucial for understanding the mechanism of regulation of pituitary hormone gene expression at the molecular level in fish. Whole pituitary gland cultures ( Yada et al . 1991 , Elango et al . 2006

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Anne-Lise Lecoq Institut National de la Santé et de la Recherche Médicale (Inserm) U1185, Le Kremlin-Bicêtre, France
Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France

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Philippe Zizzari Inserm U894, Centre de Psychiatrie et Neurosciences, Université Paris Descartes, Sorbonne Paris Cité, Paris, France

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Mirella Hage Institut National de la Santé et de la Recherche Médicale (Inserm) U1185, Le Kremlin-Bicêtre, France
Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France

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Lyvianne Decourtye Sorbonne Universités, Univ Paris 06 UMRS 938, Inserm U938, CDR Saint-Antoine, Paris, France

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Clovis Adam Assistance Publique-Hôpitaux de Paris, Service d’Anatomie et Cytologie Pathologiques, Hôpital Bicêtre, Le Kremlin Bicêtre, France

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Say Viengchareun Institut National de la Santé et de la Recherche Médicale (Inserm) U1185, Le Kremlin-Bicêtre, France
Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France

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Johannes D Veldhuis Department of Medicine, Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota, USA

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Valérie Geoffroy Inserm U1132, Hôpital Lariboisière, Université Paris Diderot, Sorbonne Paris Cité, Paris, France

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Marc Lombès Institut National de la Santé et de la Recherche Médicale (Inserm) U1185, Le Kremlin-Bicêtre, France
Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France

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Virginie Tolle Inserm U894, Centre de Psychiatrie et Neurosciences, Université Paris Descartes, Sorbonne Paris Cité, Paris, France

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Anne Guillou Unité Mixte de Recherche-5203, Centre National de la Recherche Scientifique, Institut de Génomique Fonctionnelle, Montpellier, France

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Auli Karhu Department of Medical Genetics, Genome-Scale Biology Research Program Biomedicum, University of Helsinki, Helsinki, Finland

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Laurent Kappeler Sorbonne Universités, Univ Paris 06 UMRS 938, Inserm U938, CDR Saint-Antoine, Paris, France

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Philippe Chanson Institut National de la Santé et de la Recherche Médicale (Inserm) U1185, Le Kremlin-Bicêtre, France
Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
Assistance Publique-Hôpitaux de Paris, Service d’Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, Le Kremlin Bicêtre, France

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Peter Kamenický Institut National de la Santé et de la Recherche Médicale (Inserm) U1185, Le Kremlin-Bicêtre, France
Université Paris-Sud, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France
Assistance Publique-Hôpitaux de Paris, Service d’Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, Le Kremlin Bicêtre, France

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Introduction Since 2006, mutations in the AIP (aryl hydrocarbon receptor-interacting protein) gene have been known to predispose humans to pituitary adenomas ( Vierimaa et al. 2006 ). Heterozygous mutations are found in 20% of familial

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Eun-Jin Kang Department of Biomaterials Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Milyang, Republic of Korea

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So-Hye Hong Department of Biomaterials Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Milyang, Republic of Korea

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Jae-Eon Lee Department of Biomaterials Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Milyang, Republic of Korea

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Seung Chul Kim Department of Obstetrics and Gynecology, Biomedical Research Institute, Pusan National University School of Medicine, Milyang, Republic of Korea

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Hoe-Saeng Yang Department of Obstetrics and Gynecology, Medical College, Dongguk University, Seoul, Republic of Korea

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Pyong in Yi Department of Bioenvironmental Energy, College of Natural Resources and Life Science, Pusan National University, Milyang, Republic of Korea

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Sang-Myeong Lee College of Environmental and Bioresource Sciences, Chonbuk National University, Jeonju, Republic of Korea

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Beum-Soo An Department of Biomaterials Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Milyang, Republic of Korea

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Introduction Prolactin (PRL) is a polypeptide hormone synthesized and secreted from specialized cells of the anterior pituitary gland, which is known for its multiple effects on the female mammary gland, including regulation of growth and

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B Shan
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C Schaaf
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A Schmidt
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K Lucia
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M Buchfelder Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany

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M Losa Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany

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D Kuhlen Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany

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J Kreutzer Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany

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M J Perone Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany
Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany

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E Arzt Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany
Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany

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G K Stalla
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U Renner
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applied in recent studies ( Thomas et al . 2008 , Shahani et al . 2010 ), may overcome this problem in the future. Tumours of the anterior pituitary represent the second most frequent type of intracranial neoplasms and are mostly benign adenomas derived

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Michael Muchow
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Ioannis Bossis
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Tom E Porter
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role in the hypothalamic–pituitary–thyroid (HPT) axis in mammals. However, due to a lack of homologous antisera to TSH in birds and the only recent description of an anti-peptide antibody ( Iwasawa et al. 2002 ), the physiological role of TSH in the

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Hyun Joon Kim Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Mary C Gieske Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Susan Hudgins Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Beob Gyun Kim Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Andree Krust Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Pierre Chambon Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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CheMyong Ko Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA
Division of Clinical and Reproductive Sciences, Department of Anatomy and Neurobiology, Animal Sciences, Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS, INSERM, ULP, College de France) and Institut Clinique de la Souris, Department of Clinical Sciences, University of Kentucky, Lexington, Kentucky 40536, USA

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Introduction It is well established that, among multiple factors that contribute to the induction of luteinizing hormone (LH) secretion, the ovarian steroid estrogen plays a pivotal role by exerting positive feedback to the pituitary ( Clarke 2002

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Norbert Chauvet Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Taoufik El-Yandouzi Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Marie-Noëlle Mathieu Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Audrey Schlernitzauer Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Evelyne Galibert Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Chrystel Lafont Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Paul Le Tissier Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Iain C Robinson Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Patrice Mollard Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Nathalie Coutry Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France
Département d'Endocrinologie, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universités Montpellier I and II, Division of Molecular Neuroendocrinology, Institut de Génomique Fonctionnelle, 141 Rue de la Cardonille, 34094 Montpellier Cedex 05, France

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Introduction The anterior pituitary is a complex endocrine gland that transfers information between the brain and peripheral tissues, playing a pivotal role in the regulation of physiological functions such as reproduction, metabolism, and growth

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