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, nesfatin-1 was demonstrated to be co-localized with oxytocin within the SON and PVN ( Foo et al. 2008 , Kohno et al. 2008 ). The excitability of oxytocinergic neurons of the PVN was influenced by nesfatin-1 in vitro ( Price et al. 2008 a
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. 2009 , Otto et al . 2008 ). In addition, GPR30 is expressed in oxytocin (OXT) neurones of the rat hypothalamic paraventricular nucleus (PVH) and supraoptic nucleus (SON), implicating a role for GPR30 in the fast, non-genomic actions of E 2 on OXT
Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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Orthopaedics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Department of Physiology, Jichi Medical School, Tochigi 329-0498, Japan
Department of Third Internal Medicine, Miyazaki University, Miyazaki 889-1692, Japan
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in the supraoptic nucleus (SON), which contains magnocellular neurosecretory cells (MNCs) that produce arginine vasopressin (AVP) and oxytocin (OXT) in rats ( Lee et al. 1999 , Dun et al. 2003 , Levine et al. 2005 ). However, there are few
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investigate the expression of natriuretic peptides, NOS and cGMP in the rat LV throughout gestation and early postpartum. Because of their contribution to ANP and NO release in the cardiovascular system, estrogen and oxytocin receptors (OTR) were also
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Department of Reproductive Immunology and Pathology, The Interdisciplinary Centre of Research in Animal Health, Institute of Animal Reproduction and Food Research, Olsztyn, Poland
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). Oxytocin (OT; 10 −7 M) was used as a positive control as described recently ( Szóstek et al . 2012 a , b ). In the above-mentioned study, we showed that epithelial as well as stromal cells are capable of producing PG in response to OT ( Szóstek et al
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expression at this time ( Zhang et al . 1996 , Gibb et al . 2000 , McClaren et al. 2000 ). In the uterus and placenta PG production and release can be modulated by a variety of physiological and pharmacological stimuli, for example oxytocin (OT; Lee
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octapeptide hormone angiotensin II (ANGII) also induces vasopressin (AVP) and oxytocin (OT) secretion when injected into the brain ( Antunes-Rodrigues et al . 2004 , Almeida-Pereira et al . 2016 ). OT and AVP are synthesized by magnocellular neurosecretory
Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA
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Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA
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1B (IL1B ( Il1B ), Mm00434228_m1), cyclooxygenase 2 (COX2 ( Ptgs2 ), Mm00478374_m1), iNOS ( Nos2 , Mm00440502_m1), oxytocin receptor ( Oxtr , Mm01182684_m1), Creb3 (Mm00457268_m1), and steroid receptor coactivator 2 (SRC2 ( Ncoa2 ), Mm00500749_m1
Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Department of Physiology and Genetic Regulation, National Institute of Agrobiological Sciences, Ibaraki 305-0901, Japan
Departments of Food Technology and
Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn 10-747, Poland
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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of endometrial cells have the capacity to produce PGs, they have specific morphological and physiological properties ( Asselin et al. 1997 , Fortier et al. 1988 , Miyamoto et al. 2000 ). We found that oxytocin (OT) stimulates PG production
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Institute of Experimental Medicine, Institut für Biochemie and Zellbiologie, Centre for Behavioral Brain Sciences, Hungarian Academy of Sciences, Szigony 43, 1083 Budapest, Hungary
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to defined stressors, lactating rats exhibit – compared with virgin females – reduced ACTH, corticosterone, prolactin, catecholamine, and oxytocin (OT) responses. In the PVN of lactating rats, Crh mRNA levels fail to increase in response to a