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Erica Gentilin Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy
Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Federico Tagliati Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Massimo Terzolo Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Matteo Zoli Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Marcello Lapparelli Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Mariella Minoia Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Maria Rosaria Ambrosio Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Ettore C degli Uberti Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy
Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Maria Chiara Zatelli Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy
Section of Endocrinology, Laboratorio in Rete del Tecnopolo Tecnologie delle Terapie Avanzate (LTTA), Division of Internal Medicine I, Department of Neurosurgery, Neurosurgery Unit, Department of Medical Sciences, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy

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Introduction Cushing's disease (CD), characterized by hypercortisolism due to excessive secretion of ACTH by the pituitary gland, is a rare disease with an incidence between 0.7 and 2.4 cases per million per year ( Patil et al . 2008

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0210
Volume/Issue:
Volume 218: Issue 3
Free access
Petra Popovics Department of Anatomy, School of Medicine, Medical School, University of Pecs, 12 Szigeti Street, Pecs 7624, Hungary
Department of Anatomy, School of Medicine, Medical School, University of Pecs, 12 Szigeti Street, Pecs 7624, Hungary

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Zoltan Rekasi Department of Anatomy, School of Medicine, Medical School, University of Pecs, 12 Szigeti Street, Pecs 7624, Hungary

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Alan J Stewart Department of Anatomy, School of Medicine, Medical School, University of Pecs, 12 Szigeti Street, Pecs 7624, Hungary

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Magdolna Kovacs Department of Anatomy, School of Medicine, Medical School, University of Pecs, 12 Szigeti Street, Pecs 7624, Hungary

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Introduction Activin, inhibin, and follistatin are key regulators of pituitary FSH production. These factors, together with ovarian steroids and GnRH, define the diverse pattern of LH and FSH secretion. Based on their ability to modulate FSH

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-10-0485
Volume/Issue:
Volume 210: Issue 1
Free access
Alejandro Ibáñez-Costa Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, UK

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Márta Korbonits Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, UK

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Introduction Pituitary adenomas are usually benign tumours of the anterior pituitary, which represent 15.5% of intracranial neoplasms ( Ostrom et al . 2015 ). They are frequently associated with severe comorbidities due to mass effect and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-17-0254
Volume/Issue:
Volume 235: Issue 3
Free access
Dong-Xu Han Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Chang-Jiang Wang Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Xu-Lei Sun Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Jian-Bo Liu Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Hao Jiang Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Yan Gao Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Cheng-Zhen Chen Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Bao Yuan Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Jia-Bao Zhang Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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circRNAs in bovine cumulus cells ( Fu et al. 2018 ). As an important class of experimental animals, rats play a crucial role in many types of functional studies, particularly in reproductive development ( Han et al. 2017 a ). The pituitary is an

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0540
Volume/Issue:
Volume 240: Issue 3
Free access
Tony M Plant Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh School of Medicine, 204 Craft Avenue, Room B311, Pittsburgh, Pennsylvania 15213, USA

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evidence upon which they were based, on the neural mechanisms controlling the pituitary–gonadal axis. That gonadal function was under control by the CNS was well established at the time of Harris' monograph, as was the recognition of the gonad

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-15-0113
Volume/Issue:
Volume 226: Issue 2
Free access
Débora Cristina de Moraes
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Mario Vaisman Laboratório de Endocrinologia Molecular, Hospital Universitário Clementino Fraga Filho, Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Rio de Janeiro CEP 21949-900, Brasil

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Flavia Lucia Conceição Laboratório de Endocrinologia Molecular, Hospital Universitário Clementino Fraga Filho, Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Rio de Janeiro CEP 21949-900, Brasil

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Tânia Maria Ortiga-Carvalho
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Introduction The pituitary gland comprises two parts: posterior and anterior. The posterior pituitary, or neurohypophysis, has a neuronal origin and is responsible for storing and secreting antidiuretic hormone and oxytocin, which are produced by

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0229
Volume/Issue:
Volume 215: Issue 2
Free access
Takahiro Nemoto Department of Physiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan

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Naoko Yamauchi Department of Physiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan

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Tamotsu Shibasaki Department of Physiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan

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unclarified. We previously demonstrated that Ucn 2 is expressed in the corticotrophs of rat pituitary but the concentrations of Ucn 2 in culture media of rat anterior pituitary cells are extremely low compared with those of ACTH ( Nemoto et al . 2007 ). We

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0467
Volume/Issue:
Volume 201: Issue 1
Free access
Jens Mittag Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany
Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany

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Wiebke Oehr Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany

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Heike Heuer Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany

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Tuula Hämäläinen Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany

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Bent Brachvogel Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany

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Ernst Pöschl Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany

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Karl Bauer Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany
Max Planck Institute for Experimental Endocrinology, Department of Cell and Molecular Biology, Fritz-Lipmann-Institut, Institute of Biomedicine, Institute for Biochemistry, University of East Anglia, Feodor-Lynen-Str. 7, D-30625 Hannover, Germany

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the anterior pituitary ( Traverso et al . 1999 , Kawaminami et al . 2002 ), the master gland of the endocrine system. We were therefore interested in studying the expression of the annexins in the anterior pituitary not only in wild-type animals but

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0042
Volume/Issue:
Volume 195: Issue 3
Free access
L A Nolan Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK

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A Levy Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK

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Introduction The anterior pituitary, like many other endocrine tissues, retains considerable plasticity throughout adult life. The precise quantitative and qualitative nature of any pituitary mitotic and/or apoptotic response is influenced by the

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0474
Volume/Issue:
Volume 200: Issue 3
Open access
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Raúl M Luque Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain
Department of Cell Biology, Physiology and Immunology, University of Córdoba, Cordoba, Spain
Hospital Universitario Reina Sofia (HURS), Cordoba, Spain
CIBER de la Fisiopatología de la Obesidad y Nutrición (CIBERobn), Madrid, Spain

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Rhonda D Kineman Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago and Research and Development Division, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, USA

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NST are common to SST ( Samson et al. 2008 , Hua et al. 2009 ). In spite of the genetic and putative functional link between NST and SST, the actions of NST on pituitary function, also known as the ‘master gland’ of the body, has not been explored

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0135
Volume/Issue:
Volume 237: Issue 3
Free access