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Jodi L Downs Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon 97006 and Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, Oregon 97239, USA

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Henryk F Urbanski Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon 97006 and Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, Oregon 97239, USA

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). Unlike their old male counterparts and young females, the old peri- and post-menopausal females had relatively constant levels of plasma leptin across the day and night. However, this aging-related sexual dimorphism was not evident in all of the old

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06745
Volume/Issue:
Volume 190: Issue 1
Free access
Evelyn Davies Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK

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Selma Omer Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK

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John F Morris Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK

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Helen C Christian Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK

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1991 ). Sexual dimorphism in corticosterone secretion is well established: female rodents display elevated corticosterone secretion in basal and some stress conditions relative to males ( Critchlow et al. 1963 ). Furthermore, estrogen exerts

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-06-0132
Volume/Issue:
Volume 192: Issue 2
Free access
Galya Vassileva
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Weiwen Hu
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Lizbeth Hoos Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Glen Tetzloff Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Shijun Yang
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Li Liu Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Ling Kang Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Harry R Davis Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Joseph A Hedrick Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Hong Lan Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Timothy Kowalski Merck Research Laboratories, Merck Research Laboratories, Department of Discovery Technologies, Kenilworth, New Jersey 07033, USA

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Eric L Gustafson
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glucose homeostasis in the BAT, WAT, and livers of Gpbar1 −/− and Gpbar1 + / + mice on HFD did not reveal more than 2.5-fold changes between KO and WT control mice ( Supplementary Figures 1B, C and 2 ). Sexual dimorphism in HFD-induced obesity and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0009
Volume/Issue:
Volume 205: Issue 3
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María E Díaz
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Johanna G Miquet
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Soledad P Rossi Departamento de Química Biológica, Instituto de Biología y Medicina Experimental, Facultad de Farmacia y Bioquímica, Instituto de Química y Fisicoquímica Biológicas (UBA‐CONICET), Universidad de Buenos Aires, Junín 956, 1113 Ciudad de Buenos Aires, Argentina

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Pablo E Irene
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Ana I Sotelo
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Mónica B Frungieri Departamento de Química Biológica, Instituto de Biología y Medicina Experimental, Facultad de Farmacia y Bioquímica, Instituto de Química y Fisicoquímica Biológicas (UBA‐CONICET), Universidad de Buenos Aires, Junín 956, 1113 Ciudad de Buenos Aires, Argentina

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Daniel Turyn
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Lorena González
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humans . American Journal of Physiology. Endocrinology and Metabolism 283 1008 – 1015 . ( doi:10.1152/ajpendo.00513.2001 ) Jansson JO Edén S Isaksson O 1985 Sexual dimorphism in the control of growth hormone secretion . Endocrine Reviews

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0447
Volume/Issue:
Volume 221: Issue 2
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Campbell J L Harter School of Human Sciences, The University of Western Australia, Perth, Western Australia, Australia

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Georgia S Kavanagh School of Human Sciences, The University of Western Australia, Perth, Western Australia, Australia

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Jeremy T Smith School of Human Sciences, The University of Western Australia, Perth, Western Australia, Australia

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arrangement and development of kisspeptin neurons using male and female mice. They found that kisspeptin neuronal cell bodies existed primarily in the ARC and RP3V. They also noticed a sexual dimorphism in the number of kisspeptin neurons present in the RP3V

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-18-0108
Volume/Issue:
Volume 238: Issue 3
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Branka Šošić-Jurjević
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Branko Filipović
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Kostja Renko Department of Cytology, Institut für Experimentelle Endokrinologie, Institute for Biological Research ‘Siniša Stanković’, University of Belgrade, Despot Stefan Boulevard 142, 11000 Belgrade, Serbia

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Vladimir Ajdžanović
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Milica Manojlović-Stojanoski
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Verica Milošević
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Josef Köhrle Department of Cytology, Institut für Experimentelle Endokrinologie, Institute for Biological Research ‘Siniša Stanković’, University of Belgrade, Despot Stefan Boulevard 142, 11000 Belgrade, Serbia

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higher incidence of thyroid dysfunction and carcinomas than men ( Ron et al . 1987 ). However, elderly men with thyroid carcinomas have much worse prognosis than women ( Morganti et al . 2005 ). In animal models, rats in particular, sexual dimorphism is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0336
Volume/Issue:
Volume 215: Issue 2
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Astrid Chamson-Reig Lawson Health Research Institute, St Joseph’s Health Care, 268 Grosvenor Street Room H404, London, Ontario, Canada N6A 4V2
Departments of Medicine,
Physiology and Pharmacology,
Paediatrics, University of Western Ontario, London, Ontario, Canada N6A 4V2

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Sandra M Thyssen Lawson Health Research Institute, St Joseph’s Health Care, 268 Grosvenor Street Room H404, London, Ontario, Canada N6A 4V2
Departments of Medicine,
Physiology and Pharmacology,
Paediatrics, University of Western Ontario, London, Ontario, Canada N6A 4V2

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Edith Arany Lawson Health Research Institute, St Joseph’s Health Care, 268 Grosvenor Street Room H404, London, Ontario, Canada N6A 4V2
Departments of Medicine,
Physiology and Pharmacology,
Paediatrics, University of Western Ontario, London, Ontario, Canada N6A 4V2

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David J Hill Lawson Health Research Institute, St Joseph’s Health Care, 268 Grosvenor Street Room H404, London, Ontario, Canada N6A 4V2
Departments of Medicine,
Physiology and Pharmacology,
Paediatrics, University of Western Ontario, London, Ontario, Canada N6A 4V2

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the adults at age 50 with a profound sexual dimorphism, the relative obesity being seen in the females but not in the males ( Ravelli et al. 1999 ). Dietary modifications in early life, such as altered composition, excess or restricted intake

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06754
Volume/Issue:
Volume 191: Issue 1
Free access
S Morimoto Instituto Nacional de Ciencias Médicas y Nutrición, SZ Vasco de Quiroga 15, Tlalpan 14000, D F México, México
Facultad de Química and
Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Coyoacan 04510, D F México, México

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C A Mendoza-Rodríguez Instituto Nacional de Ciencias Médicas y Nutrición, SZ Vasco de Quiroga 15, Tlalpan 14000, D F México, México
Facultad de Química and
Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Coyoacan 04510, D F México, México

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M Hiriart Instituto Nacional de Ciencias Médicas y Nutrición, SZ Vasco de Quiroga 15, Tlalpan 14000, D F México, México
Facultad de Química and
Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Coyoacan 04510, D F México, México

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M E Larrieta Instituto Nacional de Ciencias Médicas y Nutrición, SZ Vasco de Quiroga 15, Tlalpan 14000, D F México, México
Facultad de Química and
Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Coyoacan 04510, D F México, México

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P Vital Instituto Nacional de Ciencias Médicas y Nutrición, SZ Vasco de Quiroga 15, Tlalpan 14000, D F México, México
Facultad de Química and
Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Coyoacan 04510, D F México, México

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M A Cerbón Instituto Nacional de Ciencias Médicas y Nutrición, SZ Vasco de Quiroga 15, Tlalpan 14000, D F México, México
Facultad de Química and
Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Coyoacan 04510, D F México, México

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progressive hyperglycemia, accompanied by lymphocytic infiltration of pancreatic islets. In some basic aspects, this model mimics recent-onset IDDM in human patients ( O’Brien et al. 1996 ). There is evidence of sexual dimorphism in the incidence and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06357
Volume/Issue:
Volume 187: Issue 2
Free access
Melody L Allensworth-James Department of Neurobiology and Developmental Sciences, College of Medicine University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Angela Odle Department of Neurobiology and Developmental Sciences, College of Medicine University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Anessa Haney Department of Neurobiology and Developmental Sciences, College of Medicine University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Melanie MacNicol Department of Neurobiology and Developmental Sciences, College of Medicine University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Angus MacNicol Department of Neurobiology and Developmental Sciences, College of Medicine University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Gwen Childs Department of Neurobiology and Developmental Sciences, College of Medicine University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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at PND 8–10 corresponds with the reduction in GH at PND 8 in those females. Since Pou1f1 is also reduced at PND 15, we need to investigate whether or not Pou1f1 remains down throughout development in this model. We do see sexual dimorphism of Pou1f1

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0238
Volume/Issue:
Volume 238: Issue 3
Free access
Takeshi Iwasa Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Toshiya Matsuzaki Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Masahiro Murakami Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Riyo Kinouchi Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Ganbat Gereltsetseg Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Shinobu Fujisawa Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Akira Kuwahara Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Toshiyuki Yasui Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Minoru Irahara Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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putative physiopathological implications . Peptides 30 139 – 145 doi:10.1016/j.peptides.2008.06.007 . Clarkson J Herbison AE 2006 Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0129
Volume/Issue:
Volume 207: Issue 2
Free access