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E Oliveira Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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E G Moura Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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A P Santos-Silva Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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A T S Fagundes Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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A S Rios Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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Y Abreu-Villaça Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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J F Nogueira Neto Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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M C F Passos Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute
Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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P C Lisboa Department of Physiological Sciences, Laboratory of Lipids, Department of Applied Nutrition, Roberto Alcantara Gomes Biology Institute

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hypothalamic–pituitary dysfunction, with reduced thyrotropin-releasing hormone (TRH)–TSH production and/or release or TRH action on the pituitary. In the present study, we can not explain whether the effect of programing by maternal NIC exposure is caused by a

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0020
Volume/Issue:
Volume 202: Issue 3
Free access
Stefan Groeneweg Department of Internal Medicine and Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands

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Robin P Peeters Department of Internal Medicine and Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands

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Theo J Visser Department of Internal Medicine and Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands

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W Edward Visser Department of Internal Medicine and Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands

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biochemical abnormalities in myxedematous patients (Pitt-Rivers 1955, 1956, Trotter 1955 , 1956 ). Later studies showed that TA 3 potently reduces TSH secretion and TRH-receptor expression in mouse thyrotropic pituitary tumor cells ( Gershengorn et al

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-17-0113
Volume/Issue:
Volume 234: Issue 2
Free access
Marc Schneeberger Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain

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Ramon Gomis Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain

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Marc Claret Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain

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( Stanley et al . 1986 , Kim et al . 2000 ). Part of these effects are mediated by a subset of neurons that express thyrotropin-releasing hormone (TRH), which are activated by α-MSH and inhibited by AGRP ( Fekete et al . 2000 , 2004 ). Another relevant

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-13-0398
Volume/Issue:
Volume 220: Issue 2
Free access
Renata Lopes Araujo
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Bruno Moulin de Andrade
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Álvaro Souto Padron de Figueiredo
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Monique Leandro da Silva
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Michelle Porto Marassi
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Valmara dos Santos Pereira
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Eliete Bouskela Laboratório de Fisiologia Endócrina do Instituto de Biofísica Carlos Chagas Filho, Laboratório de Pesquisas em Microcirculação, Universidade Federal do Rio de Janeiro, Rio de Janeiro, CEP 21949-900, Brazil

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Denise P Carvalho
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controlling body mass ( Oh & Kaplan 1994 , Moreno et al . 2003 , Lanni et al . 2005 , Villicev et al . 2007 ). Decreased thyroid function seems to be related to impaired thyrotropin-releasing hormone (TRH) and thyroid-stimulating hormone (TSH) secretion

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0125
Volume/Issue:
Volume 198: Issue 1
Free access
Caitlin S Wyrwoll School of Human Sciences, University of Western Australia, Crawley, Western Australia, Australia
Telethon Kids Institute, Perth, Australia
Healthy Environments and Lives (HEAL) Network

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Sports Medicine 53 799 – 805 . ( https://doi.org/10.1136/bjsports-2017-097914 ) Regnault TRH de Vrijer B Galan HL Davidsen ML Trembler KA Battaglia FC Wilkening RB & Anthony RV 2003 The relationship between transplacental O2 diffusion and placental

Article Type:
Review Article
Collections:
Rising Stars special collection
DOI:
https://doi.org/10.1530/JOE-23-0030
Volume/Issue:
Volume 259: Issue 1
Free access
Francisco J Arjona Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands

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Luis Vargas-Chacoff Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands
Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands

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María P Martín del Río Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands

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Gert Flik Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands

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Juan M Mancera Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands

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Peter H M Klaren Department of Animal Physiology, Departamento de Biología, Instituto de Zoología, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands

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-to-T 3 conversion. However, we cannot exclude a feedback mechanism in which cortisol reduces the activity of hypothalamic corticotropin-releasing hormone (CRH), urotensin-I (UI), and thyrotropin-releasing hormone (TRH), factors with both

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-10-0416
Volume/Issue:
Volume 208: Issue 3
Free access
Edra London Section on Endocrinology and Genetics WEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Michelle Bloyd Section on Endocrinology and Genetics WEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Constantine A Stratakis Section on Endocrinology and Genetics WEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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-depth review see Schwartz et al. (2000) . PKA is an integral mediator of this dichotomous hypothalamic system at multiple junctions because GPCRs mediate the actions of the primary targets of NPY and melanocortin: thyrotropin-releasing hormone (TRH

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-20-0035
Volume/Issue:
Volume 246: Issue 3
Free access
Clive W Coen Reproductive Neurobiology, Division of Women's Health, School of Medicine, King's College London, London SE1 1UL, UK

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YEARS OF NEUROENDOCRINOLOGY: TRH, the first hypophysiotropic releasing hormone isolated: control of the pituitary–thyroid axis . Journal of Endocrinology 226 T85 – T100 . ( doi:10.1530/JOE-15-0124 ) Leng G Pineda R Sabatier N Ludwig M 2015

Article Type:
Editorial
DOI:
https://doi.org/10.1530/JOE-15-0251
Volume/Issue:
Volume 226: Issue 2
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Riccardo Dore Department of Internal Medicine I, Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Lübeck, Germany

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Luka Levata Department of Internal Medicine I, Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Lübeck, Germany

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Hendrik Lehnert Department of Internal Medicine I, Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Lübeck, Germany

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Carla Schulz Department of Internal Medicine I, Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Lübeck, Germany

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-releasing hormone (TRH) in mediating nesfatin-1’s effects was investigated ( Gotoh et al. 2013 ). Histamine is known to potently reduce appetite and ( Masaki et al. 2004 ) and NUCB2/nesfatin-1 was found to be expressed in the tuberal hypothalamic area (THA

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0361
Volume/Issue:
Volume 232: Issue 1
Free access
Giampaolo Trivellin Department of Endocrinology, Endocrinology Division, Bart's and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, UK
Department of Endocrinology, Endocrinology Division, Bart's and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, UK

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Márta Korbonits Department of Endocrinology, Endocrinology Division, Bart's and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, UK

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(MIM# 190160) gene encodes three isoforms, β1, β2 and β3 ( Cheng et al . 2010 ). TRβ1 is involved in the negative feedback of T 3 on TRH production in the paraventricular nucleus (PVN) but also mediates the T 3 -independent activation of TRH

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0054
Volume/Issue:
Volume 210: Issue 2
Free access