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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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National Hormone and Peptide Program, Harbor-UCLA Medical Center, Torrence, California 90509, USA
Eppley Institute for Research in Cancer and Allied Diseases and the Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198, USA
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achieved by genetic engineering such as transgenic overexpression or gene targeting. Three transgenic mouse strains have been reported to express rat prolactin under the metallothionine promoter ( Wennbo et al. 1997 a ), or the prostate-specific probasin
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
Department of Pharmacology, Göteborg University, Göteborg, Sweden
Department of Psychology, Göteborg University, Göteborg, Sweden
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Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation. PNAS 94 14054 –14059. Kuhn R , Schwenk F, Aguet M & Rajewsky K 1995 Inducible gene
INSERM, UMR_S 1138, Teams 1, Centre de Recherche des Cordeliers, UPMC Univ Paris 06, Université Paris Descartes, Paris, France
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Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy
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-1541 ) 20068130 10.2337/db09-1541 Lee KY Russell SJ Ussar S Boucher J Vernochet C Mori MA Smyth G Rourk M Cederquist C Rosen ED , 2013 Lessons on conditional gene targeting in mouse adipose tissue . Diabetes 62 864 – 874 . ( https://doi.org/10.2337/db
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al . 2007 ). In general, ossification symptoms are a classical AHO feature, as they can occur upon mutations of the maternal or paternal allele. Loss of paternally expressed XLα s (through gene targeting of the Gnasxl -specific exon) causes
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I.N.B.B. – Istituto Nazionale Biostrutture e Biosistemi, Rome, Italy
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I.N.B.B. – Istituto Nazionale Biostrutture e Biosistemi, Rome, Italy
Gynecologic Endocrinology Research Unit, Department of Experimental and Clinical Biomedical Sciences ‘Mario Serio’, University of Florence, Florence, Italy
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Gene targeting in rabbits: single-step generation of knock-out rabbits by microinjection of CRISPR/Cas9 plasmids . Methods in Molecular Biology 1630 109 - 120 . 10.1007/978-1-4939-7128-2_10 Kelley DE He J Menshikova EV Ritov VB 2002
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The Institute for Pharmacology and Toxicology, University of Bonn, Bonn, Germany
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-CA023100 (UCSD Gene Targeting Mouse Core), P30-NS047101 (UCSD Neuroscience Microscopy Shared Facility) and P30-AR04603 (University of Alabama, Birmingham, Center for Metabolic Bone Disease). N S was supported by the Deutsche Forschungsgemeinschaft
St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK
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Swanson A Kloczko E Boyd M Barker H Avdic-Belltheus A Martin J Zachary I Peebles D 2016 Gene targeting to the uteroplacental circulation of pregnant guinea pigs . Reproductive Sciences 23 1087 – 1095 . ( doi:10
Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
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Waseda Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
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Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
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Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
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Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas, USA
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Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
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Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
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Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
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Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
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Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA
Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas, USA
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.komp.org ; VG10539). The University of Kansas Medical Center Transgenic and Gene-targeting Facility (Kansas City, KS, USA) injected the mutant ES cells into C57BL/6 blastocysts. Germline-competent chimeras were generated on C57BL/6 background, and the mutation
University of Groningen, University Medical Center, Groningen, The Netherlands
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14 675 – 689 . ( doi:10.1046/j.0953-816x.2001.01685.x ) Datson NA Morsink MC Meijer OC de Kloet ER 2008 Central corticosteroid actions: Search for gene targets . European Journal of Pharmacology 583 272 – 289 . ( doi:10
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vitro , but concerns over the systemic effects associated with retinoid use need to be carefully considered. While exogenous expression of NIS in cells has proved successful in vivo , delivery methods for gene targeting are not fully optimised and