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, enrichment analysis predicted that the circadian rhythm was the only statistically enriched KEGG pathway in the pathological liver from obese individuals compared with controls (corrected P value=0.00076). Belonging to this pathway, Period family genes
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Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia
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diurnal effects may influence APP processing in the context of the aforementioned models is unknown. Symptoms in humans suffering from AD include the disruption of their sleep cycle and day time activity. While studies on the circadian rhythm on mice in
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was evaluated by real-time PCR, basal levels were significantly higher at 12 h (0700 h) than at 2 h (2100 h) after saline treatment, suggesting a circadian rhythm of NMS mRNA levels ( Mori et al . 2005 ). On the other hand, there was no significant
INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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effects of stress and circadian rhythm on circulating GH. We also used rank plot analysis to investigate the GH pattern in bIGF1RKO +/− mice ( Kappeler et al . 2008 ) and found this long-lived mutant had extended trough periods and rarefied peaks
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Max Planck Institute of Psychiatry, Institut National de la Recherche Agronomique (INRA), University of Bordeaux, Research Group of Psychoneuroendocrinology, Kraepelinstrasse 2-10, 80804 Munich, Germany
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Max Planck Institute of Psychiatry, Institut National de la Recherche Agronomique (INRA), University of Bordeaux, Research Group of Psychoneuroendocrinology, Kraepelinstrasse 2-10, 80804 Munich, Germany
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Max Planck Institute of Psychiatry, Institut National de la Recherche Agronomique (INRA), University of Bordeaux, Research Group of Psychoneuroendocrinology, Kraepelinstrasse 2-10, 80804 Munich, Germany
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different litters per line. Animals were between 3 and 5 months of age during the experiments. All experiments were performed during the trough of the circadian rhythm of GC secretion (between 0900 and 1200 h, Touma et al . (2009) ) and the order of
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Department of Biological Sciences, Laboratory of Biosystems, Federal University of São Paulo, Diadema, São Paulo, Brazil
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pancreatic islets . American Journal of Physiology 276 C507 – C510 . Peschke E Peschke D 1998 Evidence for a circadian rhythm of insulin release from perifused rat pancreatic islets . Diabetologia 41 1085 – 1092 . ( doi:10.1007/s
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clearly warranted in order to determine the modulatory effects of both the estrogens and progesterone. A circadian relationship between melatonin and leptin concentrations was reported earlier by Gündüz (2002) who suggested that photoperiod
Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
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Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
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Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
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Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
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Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
Institut National de la Santé et de la Recherche Médicale, Commissariat à l'Energie Atomique, Université Joseph Fourier, Unité 878, Grenoble, France
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where it affects circadian rhythm, and in the seminiferous tubules of the testis ( Wechselberger et al . 1999 , Melchiorri et al . 2001 , Cheng et al . 2002 , LeCouter et al . 2003 a , b ). Moreover, the distinct patterns of expression of both
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Department of Endocrinology and Metabolic Diseases, TNO-Metabolic Health Research, Leiden University Medical Center, Room C5-R61, Albinusdreef 2, PO Box 9600, 2300 RC Leiden, The Netherlands
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corticosterone levels both acutely and in the long term A diurnal corticosterone rhythm was observed in all animals, with a nadir in the morning (0700 h) and with peak values during the last light hour before the dark phase (1800 h). The HFD decreased plasma
INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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/C rats. We first measured plasma corticosterone in basal inactive and active phases of the circadian rhythm. In both cases, the vitamin A deficiency induced an increase in HPA axis activity, which was restored to control level by the supplementation