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Sarah L Armour Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Denmark

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Jade E Stanley Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

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James Cantley Division of Cellular and Systems Medicine, School of Medicine, University of Dundee, UK

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E Danielle Dean Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Division of Diabetes, Endocrinology, & Metabolism, Vanderbilt University Medical Center School of Medicine, Nashville, Tennessee, USA

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Jakob G Knudsen Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Denmark

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-1298 ) Rakhshandehroo M Hooiveld G Müller M & Kersten S 2009 Comparative analysis of gene regulation by the transcription factor PPARα between mouse and human . PLoS One 4 e6796 . ( https://doi.org/10.1371/journal.pone.0006796 ) Rocha DM Faloona GR

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Elliott P Brooks Barbara Davis Center for Diabetes, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA

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Lori Sussel Barbara Davis Center for Diabetes, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA

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metabolic stress and this could be due to a change in transcription factor function. To test this hypothesis, more experiments on how transcription factor gene regulation and DNA occupancy change during metabolic stress could be conducted. Using conditional

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