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Metformin as an anti-inflammatory agent: a short review

Robin Kristófi

Robin Kristófi Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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Jan W Eriksson

Jan W Eriksson Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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(TXNIP), which in turn leads to reduced cellular oxidative stress and so could exert a protective effect on vascular endothelium ( Li et al. 2015 ). Recent evidence also points to the role of metformin and AMPK in promoting autophagic flux to counteract