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Benoit Cox Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium

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Emma Laporte Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium

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Annelies Vennekens Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium

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Hiroto Kobayashi Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium
Department of Anatomy and Structural Science, Yamagata University Faculty of Medicine, Yamagata, Japan

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Charlotte Nys Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium

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Indra Van Zundert Department of Chemistry, Laboratory of Molecular Imaging and Photonics, KU Leuven, Leuven, Belgium

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Hiroshi Uji-i Department of Chemistry, Laboratory of Molecular Imaging and Photonics, KU Leuven, Leuven, Belgium

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Alizée Vercauteren Drubbel Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Brussels, Belgium

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Benjamin Beck Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Brussels, Belgium
WELBIO, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Heleen Roose Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium

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Matteo Boretto Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium

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Hugo Vankelecom Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Unit of Stem Cell Research, KU Leuven (University of Leuven), Leuven, Belgium

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Introduction The pituitary represents the master endocrine gland, producing hormones that are key regulators of fundamental physiological processes including body growth, fertility, metabolism, immunity and stress. The gland produces these

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Sara Pepe Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK
Department of Medical Biotechnologies, University of Siena, Siena, Italy

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Márta Korbonits Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Donato Iacovazzo Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Introduction The human pituitary gland consists of an anterior lobe, which derives from the oral ectoderm, and a posterior lobe, which originates from the neuroectoderm. The anterior pituitary contains five types of endocrine cells, including

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Wenxia He Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China
Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China

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Xiangyan Dai Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China
Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China

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Xiaowen Chen Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China
Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China

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Jiangyan He Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China

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Zhan Yin Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, 7 Donghu South Road, Wuhan, Hubei 430072, People's Republic of China

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Introduction The pituitary gland is a central endocrine gland that regulates the function of other organs and responds to the hypothalamic centers involved in processing external and internal stimuli. The pituitary gland of teleost fish is unique

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Scott Haston Developmental Biology and Cancer Research Programme, Birth Defects Research Centre, UCL Great Ormond Street Institute of Child Health, London, UK

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Saba Manshaei Developmental Biology and Cancer Research Programme, Birth Defects Research Centre, UCL Great Ormond Street Institute of Child Health, London, UK

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Juan Pedro Martinez-Barbera Developmental Biology and Cancer Research Programme, Birth Defects Research Centre, UCL Great Ormond Street Institute of Child Health, London, UK

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Introduction The pituitary gland is known as the master regulator of the endocrine system, a title that is justified by the numerous critical physiological functions that it regulates including growth, metabolism, stress responses and

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Dominik Simon Botermann Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Nadine Brandes Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Anke Frommhold Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Ina Heß Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Alexander Wolff Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Arne Zibat Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Heidi Hahn Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Rolf Buslei Institute of Pathology, Sozialstiftung Bamberg, Klinikum am Bruderwald, Bamberg, Germany

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Anja Uhmann Institute of Human Genetics, Molecular Developmental Genetics and Tumor Genetics Group, University Medical Center, Göttingen, Germany

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Introduction The pituitary gland is a key regulator of body homeostasis and responsible for signal exchanges between the hypothalamus and peripheral organs. Besides of the six different endocrine cell types (e.g. corticotrophs

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María Andrea Camilletti Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Alejandra Abeledo-Machado Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Jimena Ferraris Instituto de Investigaciones Biomédicas, Facultad de Medicina, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina

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Pablo A Pérez Centro de Microscopia Electrónica, Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Facultad de Ciencias Medicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Erika Y Faraoni Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Daniel Pisera Instituto de Investigaciones Biomédicas, Facultad de Medicina, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina

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Silvina Gutierrez Centro de Microscopia Electrónica, Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Facultad de Ciencias Medicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Graciela Díaz-Torga Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Introduction The involvement of estrogens in the control of pituitary function has been extensively studied (reviewed in Seilicovich 2010 ). Initially, estradiol was described to induce lactotroph proliferation through ERα; however, apoptotic

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Alejandro Ibáñez-Costa Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology and Immunology, Universidad de Córdoba, Córdoba, Spain
Hospital Universitario Reina Sofía, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Córdoba, Spain

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Esther Rivero-Cortés Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology and Immunology, Universidad de Córdoba, Córdoba, Spain
Hospital Universitario Reina Sofía, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Córdoba, Spain

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Mari C Vázquez-Borrego Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology and Immunology, Universidad de Córdoba, Córdoba, Spain
Hospital Universitario Reina Sofía, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Córdoba, Spain

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Manuel D Gahete Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology and Immunology, Universidad de Córdoba, Córdoba, Spain
Hospital Universitario Reina Sofía, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Córdoba, Spain

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Luis Jiménez-Reina Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Department of Morphological Sciences, Universidad de Córdoba, Córdoba, Spain

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Eva Venegas-Moreno Metabolism and Nutrition Unit, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS), Seville, Spain

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Andrés de la Riva Service of Neurosurgery, Hospital Universitario Reina Sofía, Córdoba, Spain

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Miguel Ángel Arráez Neurosurgical Department, Carlos Haya Hospital, Málaga, Spain

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Inmaculada González-Molero Department of Endocrinology and Nutrition, Carlos Haya Hospital, Málaga, Spain

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Herbert A Schmid Novartis Pharma AG, Novartis Institutes for Biomedical Research, Oncology, CH-4057 Basel, Switzerland

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Silvia Maraver-Selfa Service of Endocrinology and Nutrition, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain

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Inmaculada Gavilán-Villarejo Endocrinology and Nutrition Unit, Hospital Universitario Puerta del Mar, Cádiz, Spain

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Juan Antonio García-Arnés Department of Endocrinology and Nutrition, Carlos Haya Hospital, Málaga, Spain

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Miguel A Japón Department of Pathology, Hospital Universitario Virgen del Rocío, Seville, Spain

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Alfonso Soto-Moreno Metabolism and Nutrition Unit, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS), Seville, Spain

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María A Gálvez Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Service of Endocrinology and Nutrition, Hospital Universitario Reina Sofía, Córdoba, Spain

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Raúl M Luque Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology and Immunology, Universidad de Córdoba, Córdoba, Spain
Hospital Universitario Reina Sofía, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Córdoba, Spain

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Justo P Castaño Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology and Immunology, Universidad de Córdoba, Córdoba, Spain
Hospital Universitario Reina Sofía, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Córdoba, Spain

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Introduction Pituitary tumors are generally benign adenomas from a monoclonal/oligoclonal origin, which display heterogeneous clinical manifestations derived from oversecretion of a single hormone and/or size effects due to excess growth

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Takehiro Tsukada Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Tochigi, Japan

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Morio Azuma Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Tochigi, Japan

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Kotaro Horiguchi Laboratory of Anatomy and Cell Biology, Department of Health Sciences, Kyorin University, Tokyo, Japan

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Ken Fujiwara Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Tochigi, Japan

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Tom Kouki Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Tochigi, Japan

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Motoshi Kikuchi Laboratory of Natural History, Jichi Medical University School of Medicine, Tochigi, Japan

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Takashi Yashiro Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Tochigi, Japan

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pituitary gland. Our group has identified various collagen types (type I, III, IV, and VI collagens) in rat anterior pituitary gland ( Kaidzu et al. 2000 ). These collagens are distributed around endocrine cells and capillaries and support tissue

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Cuili Wang State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China
Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Xiamen, China

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Dongteng Liu State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China
Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Xiamen, China

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Weiting Chen Centre of Reproduction, Development and Aging (CRDA), Faculty of Health Sciences, University of Macau, Taipa, Macau, China

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Wei Ge Centre of Reproduction, Development and Aging (CRDA), Faculty of Health Sciences, University of Macau, Taipa, Macau, China

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Wanshu Hong State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China
Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Xiamen, China

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Yong Zhu State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China
Department of Biology, East Carolina University, Greenville, North Carolina, USA

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Shi X Chen State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China
Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Xiamen, China
State-Province Joint Engineering Laboratory of Marine Bioproducts and Technology, Xiamen University, Xiamen, China

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Introduction Gonadal steroid hormones play key roles in regulating gametogenesis, but they also exert both positive and negative feedback effects at the hypothalamic and pituitary levels. In tetrapod vertebrates, progesterone (P4) is the

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Chengyuan Lin School of Biological Sciences, University of Hong Kong, Hong Kong
Clinical Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong
YMU-HKBU Joint Laboratory of Traditional Natural Medicine, Yunnan Minzu University, Kunming, China

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Xue Jiang School of Biological Sciences, University of Hong Kong, Hong Kong

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Mulan He School of Biological Sciences, University of Hong Kong, Hong Kong

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Ling Zhao Clinical Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong

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Tao Huang Clinical Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong

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Zhaoxiang Bian Clinical Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong
YMU-HKBU Joint Laboratory of Traditional Natural Medicine, Yunnan Minzu University, Kunming, China

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Anderson O L Wong School of Biological Sciences, University of Hong Kong, Hong Kong

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Introduction Pituitary adenylate cyclase-activating polypeptide (PACAP), a member of the secretin/glucagon family, is a 38-amino acid (a.a.) peptide isolated from ovine hypothalamus with stimulatory activity on cAMP production in rat pituitary

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