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INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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INRA, Laboratory of Nutrition and Integrative Neurobiology, INSERM, Nutrition and Integrative Neurobiology, UMR1286, Université de Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France
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particularly interested in the LOU/C-inbred rat strain, which was derived from the Wistar strain and has been described as a model of healthy ageing with a long life expectancy ( Alliot et al . 2002 ) and preserved memory capacities ( Kollen et al . 2010
Department of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain
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Department of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain
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Department of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain
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Department of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain
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Department of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain
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Department of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain
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Department of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain
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, the Lou/C rat is an inbred sub-strain, derived from the Wistar rat. It is reported to exhibit spontaneous caloric restriction, relatively high energy expenditure and a lower body weight, mainly due to lower levels of white adipose tissue (WAT
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comparison of three inbred rat strains, Fischer 344 (F344), LOU/C (LOU), and Lewis (LEW). The F344 strain has been classically used as a model of HPA axis hyperactivity and hyperreactivity to stress, often in comparison with the LEW strain, of which the
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peptide PVN (mRNA) Arc (mRNA) TSH TT 4 TT 3 Cort References Trh Crh Agrp Npy Cart Pomc Bdnf Lou/C rat vs Wistar ↓ + ↑ * ↑ * ↑ * – + ↓ + ↑ ↑ ↓ – ↓ Mitchell et al
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Surgical Research Unit, Department of Surgery, Laboratory of Metabolism, Infectious Diseases Service, Clinical Diabetes Unit, Radiology, Cell Physiology and Metabolism, Internal Medicine, Department of Surgery
Surgical Research Unit, Department of Surgery, Laboratory of Metabolism, Infectious Diseases Service, Clinical Diabetes Unit, Radiology, Cell Physiology and Metabolism, Internal Medicine, Department of Surgery
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Gjinovci A Meda P Foti M Rohner-Jeanrenaud F 2009 The Lou/C rat: a model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue . American Journal of Physiology. Endocrinology
State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, China
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Shandong Sport Training Center, Jinan, China
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Soares AF Lagarde M Geloen A 2008 Lou/C obesity-resistant rat exhibits hyperactivity, hypermetabolism, alterations in white adipose tissue cellularity, and lipid tissue profiles . Endocrinology 149 615 – 625 . ( doi:10.1210/en.2007
INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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INSERM U938, Université Pierre-et-Marie-Curie, INRA, INSERM U707, Hôpital Saint-Antoine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France
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pulsatile secretion and increased orexigenic peptide expression in the Lou C/JaLL rat . Neuroendocrinology 80 273 – 283 doi:10.1159/000083610 . Kappeler L De Magalhaes Filho C Dupont J Leneuve P Cervera P Périn L Loudes C Blaise A Klein
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Jin S Lou C 2009 AIB1 is required for the acquisition of epithelial growth factor receptor-mediated tamoxifen resistance in breast cancer cells . Biochemical and Biophysical Research Communications 380 699 – 704 . ( doi:10.1016/j
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Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri, USA
Department of Child Health, University of Missouri, Columbia, Missouri, USA
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Altirriba J Montet X Colin DJ Caillon A Lyautey J Rohner-Jeanrenaud F 2015 Ectopic UCP1 overexpression in white adipose tissue improves insulin sensitivity in Lou/C Rats, a Model of Obesity Resistance Lou . Diabetes 64 3700 – 3712 . ( https