Search Results

You are looking at 11 - 20 of 1,207 items for :

  • brain development x
  • All content x
Clear All
Open access

Huali Yu, Ye Guo, Yang Zhao, Feng Zhou, Kehan Zhao, Mayuqing Li, Junxiong Wen, Zixuan He, Xiaojuan Zhu, and Xiaoxiao He

brain development and function. For instance, maternal stress-triggered GC elevation changes the fetal brain structure, leading to attention and learning deficits in adulthood ( Weinstock 2008 ). Prenatal stress is highly associated with increased

Free access

Ángel Enrique Céspedes Rubio, Maria José Pérez-Alvarez, Catalina Lapuente Chala, and Francisco Wandosell

. 2001 ). Estradiol has an important impact on brain development and normal physiology, but also after injury. Cellular targets of its action are both neurons and the main glial cell types (astrocytes, microglia, radial glia and oligodendrocytes

Free access

Andréa Gonçalves Trentin

& Robitaille 2003 , Nedergaard et al. 2003 , Bachoo et al. 2004 ). Astrocytes are mediators of thyroid hormone metabolism in the brain The importance of thyroid hormone for normal brain development is well documented

Free access

Praveen Kumar, Vishwa Mohan, Rohit Anthony Sinha, Megha Chagtoo, and Madan M Godbole

unliganded TRs, we hypothesized that inhibiting HDAC activity would block the negative regulation of target genes by unliganded TRs and may restore normal brain development under hypothyroidism. Using rat model of perinatal hypothyroidism, we here demonstrate

Free access

S Van der Geyten and V M Darras

intracellular T 3 availability in this tissue. That brain D3 activity also increased simultaneously might indicate that for the brain this increase comes at the wrong time in development and therefore the brain, through induction of the IRD pathway, takes

Free access

Yang Zhang, Weimin Zhang, Huiyi Yang, Wenliang Zhou, Chaoqun Hu, and Lihong Zhang

summary, cyp19a1a and cyp19a1b were differentially expressed in the gonad and brain of the ricefield eel, and the tissue distribution of cyp19a1b exhibited a novel sexual dimorphism. Both cyp19a1a and cyp19a1b may be involved in the ovarian development and

Free access

Ellen Kanitz, Winfried Otten, and Margret Tuchscherer

pigs, sheep and primates), maximal brain growth and a large proportion of neuroendocrine maturation (including corticosteroid receptor development) take place in utero ( Matthews 1998 , Challis et al. 2000 ). Conversely, in species that give birth

Free access

S Benvenuti, P Luciani, I Cellai, C Deledda, S Baglioni, R Saccardi, S Urbani, F Francini, R Squecco, C Giuliani, G B Vannelli, M Serio, A Pinchera, and A Peri

Introduction Thyroid hormones (TH) play a fundamental role in fetal life, particularly in promoting brain development. TH affect the expression of several genes, which are related to cell migration (i.e. reelin, laminin, tenascin C), myelination (i

Open access

Shiao Y Chan, Laura A Hancox, Azucena Martín-Santos, Laurence S Loubière, Merlin N M Walter, Ana-Maria González, Phillip M Cox, Ann Logan, Christopher J McCabe, Jayne A Franklyn, and Mark D Kilby

development. IUGR is often characterized by continued head and brain growth at the expense of other less vital organs resulting in an elevated brain:liver weight ratio postnatally ( Cox & Marton 2009 ). IUGR complicates 5–10% of pregnancies and is associated

Free access

Sean C Lema, Jon T Dickey, Irvin R Schultz, and Penny Swanson

Introduction The hypothalamic–pituitary–thyroid (HPT) axis regulates metabolism and growth, reproduction, and brain development in vertebrates. Similarly, in fish, thyroid hormones (THs) have been demonstrated to regulate growth ( Huang et al