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C R Liu, L Y Li, F Shi, X Y Zang, Y M Liu, Y Sun, and B H Kan

. Macroscopic observations revealed obvious myocardial hypertrophy and cardiac chamber narrowing in hyperthyroid rats (5/8), and heart weight was higher in the hyperthyroidism group than in the control group ( P <0.01; Tables 2 and 3 ). Table 2 Body weight

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Christopher J Charles, Miriam T Rademaker, and A Mark Richards

1997 Ovine brain natriuretic peptide in cardiac tissues and plasma: effects of cardiac hypertrophy and heart failure on tissue concentration and molecular forms. Journal of Endocrinology 155 541 –550. Rademaker MT

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Katie J Mylonas, Neil A Turner, Sumia A Bageghni, Christopher J Kenyon, Christopher I White, Kieran McGregor, Robert A Kimmitt, Richard Sulston, Valerie Kelly, Brian R Walker, Karen E Porter, Karen E Chapman, and Gillian A Gray

muscle ( Hatakeyama et al . 2001 ), mast cells ( Coutinho et al . 2013 ) and resident macrophages ( Gilmour et al . 2006 ) and fibroblasts ( Sun & Myatt 2003 ). In a recent study ( White et al . 2016 ), we reported that 11β-HSD1 deletion in cardiac

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Harman S Mattu and Harpal S Randeva

have been shown to be cardioprotective against myocardial ischaemia/reperfusion (I/R) injury and may also play a role in cardiac remodelling in pathology by limiting the extent of myocardial hypertrophy ( Ouchi et al . 2006 ). This article is intended

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Stefanie Ruhs, Alexander Nolze, Ralf Hübschmann, and Claudia Grossmann

aldosterone/MR signaling on different levels is reported in literature and spironolactone, for example, can inhibit angII-mediated pathological effects by improving cardiac and vascular changes, including fibrosis, hypertrophy and oxidative stress in rats

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Robson A S Santos, Anderson J Ferreira, Thiago Verano-Braga, and Michael Bader

concentration of this peptide 2.5-fold ( Botelho-Santos et al . 2007 ). In addition, these animals showed a slight, but significant, increase in daily and nocturnal dP/dt, more resistance to isoproterenol-induced cardiac hypertrophy, reduced duration of

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Miski Scerif, Tamás Füzesi, Julia D Thomas, Blerina Kola, Ashley B Grossman, Csaba Fekete, and Márta Korbonits

, impaired glucose tolerance, insulin resistance, dyslipidaemia, hepatic steatosis and systemic arterial hypertension, a state similar to the metabolic syndrome ( Pivonello et al . 2005 ). Cardiac abnormalities, such as left ventricular hypertrophy

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Tsun-Jui Liu, Hui-Chin Lai, Chih-Tai Ting, and Ping H Wang

survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 857 –868. Dorn GW & Force T 2005 Protein kinase cascades in the regulation of cardiac hypertrophy. Journal of Clinical Investigation

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Sonnet S Jonker, Daniel Kamna, Dan LoTurco, Jenai Kailey, and Laura D Brown

repression in the heart. How cortisol interacts with low levels of IGF1 to suppress growth or induce apoptosis in IUGR skeletal and cardiac muscle remains to be determined. Norepinephrine is a non-selective adrenergic agonist linked to hypertrophy in adult

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Mariana Renovato Martins, Anatalia Kutianski Gonzalez Vieira, Érica Patrícia Garcia de Souza, and Anibal Sanchez Moura

almost all body tissues ( Shiojima et al . 2002 ). Glucose uptake, glycogen synthesis, glycolysis, glucose oxidation, and inhibition of fatty acid oxidation are all insulin-dependent processes in various tissues including the cardiac muscle ( Carroll et