Search Results

You are looking at 81 - 90 of 100 items for :

  • "suppressor of cytokine signaling" x
  • All content x
Clear All
Free access

Christopher M Mulligan and Jacob E Friedman

suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: implications for insulin resistance . Diabetes Care 32 2281 – 2287 . ( doi:10.2337/dbib9-0979 ) Ghanim H Sia CL Upadhyay M Korzeniewski K

Free access

Sara Yosefi, Gideon Hen, Charles I Rosenblum, David J Cerasale, Michaël Beaulieu, Francois Criscuolo, and Miriam Friedman-Einat

Klingenspor M 2004 Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodopus sungorus , is reflected in arcuate nucleus SOCS-3 (suppressor of cytokine signaling) gene expression . Endocrinology 145 1185 – 1193 doi:10.1210/en

Free access

Christophe Breton

activates the expression of suppressors of cytokine signalling 3 (SOCS3) that in turn inhibits leptin-induced tyrosine phosphorylation of JAK2 and STAT3 activation (indicated in red). The direct cross talk between insulin and leptin signalling at the level

Free access

Simon J Dunmore and James E P Brown

gene expression by leptin induction of suppressor of cytokine signaling 3 in pancreatic β-cells . Diabetes 54 3410 – 3417 . ( doi:10.2337/diabetes.54.12.3410 ) Leahy JL Hirsch IB Peterson KA Schneider D 2010 Targeting β-cell function

Free access

N David Åberg, Inger Johansson, Maria A I Åberg, Johan Lind, Ulf E Johansson, Christiana M Cooper-Kuhn, H Georg Kuhn, and Jörgen Isgaard

RL Coonan JR Bartlett PF 2002 Suppressor of cytokine signaling 2 regulates neuronal differentiation by inhibiting growth hormone signaling . Nature Neuroscience 5 1155 – 1162 . Westenbroek C Den Boer JA Veenhuis M Ter Horst GJ

Free access

Barbara C Fam, Rebecca Sgambellone, Zheng Ruan, Joseph Proietto, and Sofianos Andrikopoulos

neuropeptide Y ( Npy ) and agouti related peptide ( Agrp ) and in the appetite-suppressing melanocortin pathway ( Huang et al . 2003 a , b ) were the predominant contributors, whereas other authors showed changes only in the suppressor of cytokine signalling 3

Free access

Rajat Kumar Das, Sarmistha Banerjee, and Bernard H Shapiro

contradiction with the accompanying ∼90% decline in CYP2C11 mRNA and protein. However, the episodic GH/JAK2/STAT5B signal transduction pathway is negatively regulated by tyrosine phosphatases ( Frank 2001 , Waxman & O'Connor 2006 ) and suppressors of cytokine

Free access

María E Díaz, Johanna G Miquet, Soledad P Rossi, Pablo E Irene, Ana I Sotelo, Mónica B Frungieri, Daniel Turyn, and Lorena González

number of subsets ( n ) of individual animals. Different letters denote significant differences ( P ≤0.05). Representative western blots are shown. The liver content of the suppressor of cytokine signaling CIS also varies depending on GH plasma

Free access

Misuzu Yamashita, Fumio Otsuka, Tomoyuki Mukai, Hiroyuki Otani, Kenichi Inagaki, Tomoko Miyoshi, Junko Goto, Masahiro Yamamura, and Hirofumi Makino

osteogenetic process. There has been recent evidence indicating that the effects of TNF-α are primarily associated with activation of MAPK signaling, which subsequently increases the activation of stress-related proteins such as NF-κB and suppressor of cytokine

Free access

Susan Kralisch, Anke Tönjes, Kerstin Krause, Judit Richter, Ulrike Lossner, Peter Kovacs, Thomas Ebert, Matthias Blüher, Michael Stumvoll, and Mathias Fasshauer

. FGF21-mediated suppression of STAT5 is accompanied by decreases in the expression of its target genes including IGF1 ( Inagaki et al . 2008 ). Furthermore, FGF21 induces hepatic expression of IGF1 binding protein 1 and suppressor of cytokine signaling