Search Results

You are looking at 81 - 90 of 91 items for :

  • All content x
Clear All
Free access

Mohammed Bensellam, Jean-Christophe Jonas, and D Ross Laybutt

metallothionein overexpression in β-cells, while reducing cytokine-induced ROS generation, accelerated diabetes onset in male NOD mice in association with increased β-cell death and reduced PDX1 protein levels ( Li et al . 2006 a ). It should be emphasized here

Free access

Stephen C Hanley, Béatrice Assouline-Thomas, Julia Makhlin, and Lawrence Rosenberg

therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice . Diabetes 54 2596 – 2601 . doi:10.2337/diabetes.54.9.2596 . Vinter-Jensen L Juhl CO Teglbjaerg PS Poulsen SS Dajani

Free access

A Alidibbiat, C E Marriott, K T Scougall, S C Campbell, G C Huang, W M Macfarlane, and J A M Shaw

marrow without evidence of cell fusion . Journal of Clinical Investigation 111 843 – 850 . Kodama S Kuhtreiber W Fujimura S Dale EA Faustman DL 2003 Islet regeneration during the reversal of autoimmune diabetes in NOD mice . Science 302 1223

Open access

Qinglei Yin, Liyun Shen, Yicheng Qi, Dalong Song, Lei Ye, Ying Peng, Yanqiu Wang, Zhou Jin, Guang Ning, Weiqing Wang, Dongping Lin, and Shu Wang

addition, the SIRT1 activator resveratrol has been shown to prevent and treat spontaneous type 1 diabetes, which normally develops in non-obese diabetic (NOD) mice ( Lee et al. 2011 ). In contrast, there is a paucity of studies regarding the role of SIRT1

Free access

Alessandra Fierabracci

negative ATC cells, induced tumours in vivo when injected into immunodeficient NOD/SCID mice. The CD133-positive cell pool could be separated by flow cytometry into two distinct populations: cells highly expressing CD133 and cells with low CD133

Open access

Scott Haston, Saba Manshaei, and Juan Pedro Martinez-Barbera

serially transplanted into NOD/SCID mice. Chen and coworkers were able to show similar results through isolation of CD133 and NESTIN-expressing cells from PA, which were able to initiate synaptophysin-positive tumours when xenotransplanted subcutaneously

Free access

Noèlia Téllez and Eduard Montanya

.3727/096368908786092775 ) Suarez-Pinzon WL Power RF Yan Y Wasserfall C Atkinson M Rabinovitch A 2008b Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice . Diabetes 57 3281 – 3288 . ( doi:10.2337/db08

Free access

Kleber L A Souza, Ewa Gurgul-Convey, Matthias Elsner, and Sigurd Lenzen

RF Szabo C Rabinovitch A 2001 An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice . Journal of Autoimmunity 16 449 – 455 . Tiedge M Lortz S Drinkgern J Lenzen S 1997

Free access

Maria Petropavlovskaia, Julia Makhlin, John Sampalis, and Lawrence Rosenberg

patient with new-onset type I diabetes and acts as T-cell autoantigen in NOD mice. Diabetes 51 339 –346. Hamamoto N , Ashizawa N, Niigaki M, Kaji T, Katsube T, Endoh H, Watanabe M, Sumi S & Kinoshita Y 2002 Morphological

Free access

Wenjing Wang, Lisa Upshaw, D Michael Strong, R Paul Robertson, and JoAnna Reems

cell death program. Diabetes 50 1290 –1301. Gaber AO , Fraga D, Kotb M, Lo A, Sabek O & Latif K 2004 Human islet graft function in NOD-SCID mice predicts clinical response in islet transplant recipients