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PubMed
SUMMARY
A total of twenty-three human pre-viable foetuses (7–400 g.) were removed by abdominal hysterotomy (legal abortions) and studied during survival in an anoxic state at different temperatures.
The duration of survival, as judged by ECG waves, at 37° c was about 3 hr.; it was longer for female foetuses than for males, and longer for large foetuses than for small ones. General reduction of the body-temperature to 4° c during periods varying between 30 min. and 6 hr. with subsequent rewarming to and maintenance at 37° c increased the survival time by a further 1–2 hr.
The blood sugar did not decrease either during the period of survival or during hypothermia, but the non-protein nitrogen increased, while acidosis and hyperkalaemia developed.
The glycogen content of the liver decreased during the anoxic period of survival and diminished further during hypothermia.
The adrenal glands produced adrenaline in addition to noradrenaline during the anoxic phase, and this may occur in a very early stage of intrauterine life.
