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J. R. MAINOYA
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H. A. BERN
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J. W. REGAN
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SUMMARY

Mucosal fluid, sodium and chloride transfer were measured in everted sacs of rat, guinea-pig and hamster jejunum, and in rat ileum and colon, and in guinea-pig gall bladder. After treatment of the animal with ovine prolactin, a highly significant enhancement of fluid and NaCl absorption was observed in rat, hamster and guinea-pig jejunum. Prolactin treatment caused a significant increase in fluid and NaCl transfer in rat ileum, but not in guinea-pig ileum or rat colon. Prolactin administration had no consistent effect on fluid and NaCl absorption by the guinea-pig gall bladder. The several regions of the mammalian gut appear to differ in their responsiveness to prolactin.

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