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- Author: M. H. ELLETT x
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It was observed in our laboratory that the age of onset of puberty of Long-Evans female rats differed according to their source. Animals from the University of California, Berkeley, California (U.C.B.) are reported to have an age of vaginal canalization of 39–45 days (J. Ehlert, personal communication), while animals from Simonsen Laboratories, Gilroy, California (S.L.) achieve puberty at 32–35 days (Simonsen Laboratories, personal communication). This difference of age is surprising since the S.L. rat colony was started from the U.C.B. colony in 1949. Simonsen Laboratories maintain semi-specific pathogen-free conditions, whereas no special precautions are taken in U.C.B. or San Francisco (U.C.M.C.S.F.).
This study was undertaken to determine if environmental influences affected the difference in the age of onset of puberty between rats from the two sources. Among these factors feed was considered to be important. Although the animals in both laboratories were fed on a common diet, powdered White Diet
