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  • Author: MARJORIE V. MUSSETT x
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P. MARY COTES, MARJORIE V. MUSSETT, I. BERRYMAN, R. EKINS, S. GLOVER, N. HALES, W. M. HUNTER, CLARA LOWY, R. W. J. NEVILLE, E. SAMOLS and PATRICIA M. WOODWARD

SUMMARY

Results of a collaborative study in which the insulin concentrations of a number of plasma samples were estimated in several laboratories are reported. They indicate that: (1) laboratories agreed on the ranking of plasma samples according to insulin content; (2) the reproducibility of replicate estimates obtained in the same assay usually overestimated the reproducibility of estimates made on different occasions; (3) values reported for the insulin concentration of the same plasma examined in each of a number of laboratories were likely to range from about one half to twice the inter-laboratory mean estimate.

Possible reasons for the variability of estimates are discussed.