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Natasha Singh, Bronwen Herbert, Gavin R Sooranna, Nicolas M Orsi, Lydia Edey, Tathagata Dasgupta, Suren R Sooranna, Steven M Yellon and Mark R Johnson

. Seminars in Fetal and Neonatal Medicine 15 336 – 341 . ( doi:10.1016/j.siny.2010.06.006 ) 10.1016/j.siny.2010.06.006 Streicher JM Ren S Herschman H Wang Y 2010 MAPK-activated protein kinase-2 in cardiac hypertrophy and

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Márta Szaszák, Hung-Dar Chen, Hao-Chia Chen, Albert Baukal, László Hunyady and Kevin J Catt

pathogenesis of renal diseases and several cardiovascular disorders, including hypertension, cardiac hypertrophy, and atherosclerosis, and has been implicated in the Marfan syndrome and cancer. In addition to its classical target tissues, local AngII formation

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Peter J Fuller, Jun Yang and Morag J Young

Moussa L Dilley R Funder JW 2003 Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 beta-hydroxysteroid dehydrogenase inactivation . Endocrinology 144 1121 – 1125 . ( doi:10.1210/en.2002

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Ji-Eun Kim, Seung Eun Song, Yong-Woon Kim, Jong-Yeon Kim, Sung-Chul Park, Yoon-Ki Park, Suk-Hwan Baek, In Kyu Lee and So-Young Park

.vetimm.2003.09.005 . Takimoto E Kass DA 2007 Role of oxidative stress in cardiac hypertrophy and remodeling . Hypertension 49 241 – 248 doi:10.1161/01.HYP.0000254415.31362.a7 . Tan KC Xu A Chow WS Lam MC Ai VH Tam SC Lam KS 2004

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Peter J Fuller, Yizou Yao, Jun Yang and Morag J Young

.mce.2003.10.009 . Qin W Rudolph AE Bond BR Rocha R Blomme EAG Goeliner JJ Funder JW McMahon EG 2003 Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure . Circulation Research 93 69 – 76 . doi:10.1161/01.RES

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Hans-Peter Holthoff, Kerstin Uhland, Gabor Laszlo Kovacs, Andreas Reimann, Kristin Adler, Clara Wenhart and Martin Ungerer

Graves’ disease, tachycardia and cardiac hypertrophy . Endocrinology 156 1577 – 1589 . ( https://doi.org/10.1210/en.2014-1813 ) Holthoff HP Li ZM Fassbender J Reimann A Adler K Münch G Ungerer M 2017 Cyclic peptides for effective

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Rui Song, Xiang-Qun Hu and Lubo Zhang

prematurely from spontaneous cardiovascular disease such as spontaneous cardiac hypertrophy, left ventricular dysfunction and heart failure ( Oakley et al. 2013 ). Cortisol administration directly to the near-term fetal lambs increased heart mass that was

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Harman S Mattu and Harpal S Randeva

proliferation Human in vitro (SMC) Arita et al . (2002) ↓Systolic BP Mouse in vivo Ohashi et al . (2006) ↓Pressure overload induced cardiac hypertrophy Mouse in vivo /rat ventricular myocytes Shibata et al . (2004) ↓ET-1 induced hypertrophy Rat

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Svetlana I Sofronova, Dina K Gaynullina, Anastasia A Shvetsova, Anna A Borzykh, Ekaterina K Selivanova, Daria S Kostyunina, Anna P Sharova, Andrey A Martyanov and Olga S Tarasova

nitric oxide synthase . Journal of Clinical Investigation 102 2061 – 2071 . ( doi:10.1172/JCI4394 ) 10.1172/JCI4394 Ojamaa K 2010 Signaling mechanisms in thyroid hormone-induced cardiac hypertrophy . Vascular Pharmacology 52 113 – 119

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Syed Jalal Khundmiri

cardiac myocytes increases intracellular calcium and activates a signaling cascade that involves production of ROS and activation of the EGFR–Src kinase pathway leading to cardiac hypertrophy ( Xie & Askari 2002 , Mohammadi et al . 2003 ). This