Search Results

You are looking at 91 - 100 of 619 items for :

  • Acute insulin resistance x
Clear All
Free access

Nattayaporn Apaijai, Tharnwimol Inthachai, Suree Lekawanvijit, Siriporn C Chattipakorn and Nipon Chattipakorn

-term high-fat diet (HFD) consumption could induce obese-insulin resistance ( Apaijai et al. 2012 ) and is related to an increased risk of MI ( Oh et al. 2005 ), promotion of arrhythmic death, and worsening of LV dysfunction in a myocardial ischemia

Free access

Milos Lazic, Fraser Aird, Jon E Levine and Andrea Dunaif

have an increased prevalence of hyperandrogenemia, insulin resistance, and metabolic syndrome ( Sam et al . 2005 , 2006 ). Brothers of women with PCOS have elevated levels of dehydroepiandrosterone sulfate ( Legro et al . 2002 ) and metabolic

Free access

J C Parker, K S Lavery, N Irwin, B D Green, B Greer, P Harriott, F P M O’Harte, V A Gault and P R Flatt

–42) and GLP-1(9–36)amide were examined in obese diabetic ob / ob mice. This is a commonly studied animal model displaying several abnormalities characteristic of type 2 diabetes, including obesity, insulin resistance, moderate hyperglycaemia and severe

Free access

Bruno C Pereira, Alisson L da Rocha, Ana P Pinto, José R Pauli, Leandro P de Moura, Rania A Mekary, Ellen C de Freitas and Adelino S R da Silva

Introduction The beneficial effects of acute and chronic moderate intensity exercise on the glucose metabolism in skeletal muscle cells of aging, obese, and sedentary rodents may be mediated by key proteins of the insulin-dependent signaling

Free access

Linda Ahlkvist, Bilal Omar, Anders Valeur, Keld Fosgerau and Bo Ahrén

compensate for insulin resistance by increasing insulin secretion is reduced, which leads to significant reductions in glucose clearance. However, in spite of different insulin responses, plasma glucose levels were similar between groups, which likely reflect

Free access

Camilla Alexanderson, Elias Eriksson, Elisabet Stener-Victorin, Malin Lönn and Agneta Holmäng

, Recabarren et al . 2005 , King et al . 2007 ). In a recent study, we showed that an early postnatal injection of oestradiol, testosterone or dihydrotestosterone causes insulin resistance in adult female rats, and that testosterone and oestradiol exposed

Free access

Hiranya Pintana, Nattayaporn Apaijai, Nipon Chattipakorn and Siriporn C Chattipakorn

Introduction Insulin resistance is a pathological condition in which tissues do not respond to normal physiological insulin concentrations resulting in increased insulin concentration required to maintain glucose homeostasis ( Kahn & Flier 2000

Free access

Bee K Tan, Krzysztof C Lewandowski, Joseph Paul O'Hare and Harpal S Randeva

Introduction Obesity and the metabolic syndrome are associated with insulin resistance, hyperinsulinaemia, type 2 diabetes mellitus (T2DM) and serious cardiovascular sequelae ( Eckel et al . 2005 ). Adipose tissue produces cytokines termed

Free access

Monique C Saleh, Michael B Wheeler and Catherine B Chan

weeks, insulin secretion was increased by 30-fold compared with lean mice ( P <0.001). The insulin:glucose (ins:gluc) ratio is an approximate measure of insulin resistance; the higher the ratio, the more insulin is required to maintain appropriate

Free access

Cynthia L Blanco, Alvaro G Moreira, Lisa L McGill-Vargas, Diana G Anzueto, Peter Nathanielsz and Nicolas Musi

birth weight) have a high incidence of hyperglycemia ( Blanco et al . 2006 , Beardsall et al . 2010 , Liechty 2010 ), relative insulin resistance, and defective insulin processing; however, the molecular basis for their impaired glucose metabolism