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K Boelaert and J A Franklyn

been detected in adult rat brain and a neuronal localisation in developing rat CNS has been postulated ( Friesema et al. 2004 ). However, the precise anatomical and temporal expression of MCT8 during brain development has yet to be described in

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Zahida Yesmin Roly, Andrew T Major, Alex Fulcher, Martin A Estermann, Claire E Hirst and Craig A Smith

2004 A novel signaling mechanism in brain development . Pediatric Research 309 – 310 . ( ) Piao X Hill RS Bodell A Chang BS Basel-Vanagaite L Straussberg R Dobyns WB Qasrawi B

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Daniela Leite de Oliveira, Camila Hirotsu, Sergio Tufik and Monica Levy Andersen

deprivation induced by exposure to artificial light causes several impairments in the regulation of biological rhythms, cognition and brain development, leading to long-term negative impacts on quality of life ( Thomas et al . 2000 , Durmer & Dinges 2005

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Karen Forbes and Melissa Westwood

Mester J Herich R 2009 Partial primary deficiency of insulin-like growth factor (IGF)-I activity associated with IGF1 mutation demonstrates its critical role in growth and brain development . Journal of Clinical Endocrinology and Metabolism 94

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Peter J King, Leonardo Guasti and Ed Laufer

A Alvarez-Buylla A Altaba A 2005 Sonic hedgehog controls stem cell behavior in the postnatal and adult brain . Development 132 335 – 344 . Parkin CA Ingham PW 2008 The adventures of Sonic Hedgehog in development and repair. I

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Local control of thyroid hormone action: role of type 2 deiodinase

Deiodinases: the balance of thyroid hormone

Graham R Williams and J H Duncan Bassett

.2007-0652 . Heuer H 2007 The importance of thyroid hormone transporters for brain development and function . Best Practice and Research. Clinical Endocrinology and Metabolism 21 265 – 276 doi:10.1016/j.beem.2007.03.003 . Huang H Cai L

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K A Chan, M W Tsoulis and D M Sloboda

systems including gonadal and brain development ( Forges et al . 2007 , Stover 2011 , Dwarkanath et al . 2013 , Gueant et al . 2013 ). Deficiencies in folate and/or vitamin B during pregnancy increase the risk of neural tube defects, cognitive or

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Arturo Hernandez and M Elena Martinez

promoters ( Martinez et al . 2018 ). The majority of genes associated with the most profound promoter hypomethylation are specific to brain tissue and implicated in brain development ( Martinez et al . 2018 ) and may contribute to the behavioral

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Patricia Joseph-Bravo, Lorraine Jaimes-Hoy, Rosa-María Uribe and Jean-Louis Charli

TJ Heuer H 2013 Tetrac can replace thyroid hormone during brain development in mouse mutants deficient in the thyroid hormone transporter mct8 . Endocrinology 154 968 – 979 . ( doi:10.1210/en.2012-1628 ) Ishikawa K Kakegawa T Suzuki M

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Trassanee Chatmethakul and Robert D Roghair

. ( ) 10.3945/ajcn.116.150482 Lodygensky GA Rademaker K Zimine S Gex-Fabry M Lieftink AF Lazeyras F Groenendaal F de Vries LS Huppi PS 2005 Structural and functional brain development after hydrocortisone