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Masahiro Ogawa, Tomoya Kitakaze, Naoki Harada and Ryoichi Yamaji

Inui H Nakano Y 2011 Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms . Biochemical and Biophysical Research

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Mark A Exley, Laura Hand, Donal O'Shea and Lydia Lynch

inflammation is triggered is not completely understood, but it is suggested that lipotoxicity ( Unger & Scherer 2010 ), endoplasmic reticulum (ER) stress due to excess lipid burden ( Ozcan et al . 2004 ), hypoxia due to decreased oxygen diffusion into enlarged

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Jing Li, Pan-Pan Zhao, Ting Hao, Dan Wang, Yu Wang, Yang-Zi Zhu, Yu-Qing Wu and Cheng-Hua Zhou

of Neuroscience Methods 53 55 – 63 . ( doi:10.1016/0165-0270(94)90144-9 ) Chiu CZ Wang BW Shyu KG 2014 Angiotensin II and the JNK pathway mediate urotensin II expression in response to hypoxia in rat cardiomyocytes . Journal of

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Weiwei Qin, Wenbao Lu, Hongwei Li, Xiaochen Yuan, Bingwei Li, Qiuju Zhang and Ruijuan Xiu

interactions in endothelial permeability regulation . Journal of Anatomy 200 561 – 574 . doi:10.1046/j.1469-7580.2002.00057.x . Bauer AT Burgers HF Rabie T Marti HH 2010 Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in

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Michela Campolo, Akbar Ahmad, Rosalia Crupi, Daniela Impellizzeri, Rossana Morabito, Emanuela Esposito and Salvatore Cuzzocrea

ones. Immediately following TBI, the direct trauma and the lack of blood flow cause necrotic neuronal death; however, even greater apoptotic neuronal loss occurs hours and days later, caused by secondary injury from cerebral ischemia/hypoxia as well as

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M Shimizu, J T Dickey, H Fukada and W W Dickhoff

, stage and/or physiologic condition. Expression of fish IGFBP-1 is influenced by fasting and hypoxia ( Gracey et al. 2001 , Maures & Duan 2002 ). In the present study, we found that expression of 22 kDa IGFBP in the liver was influenced by possible

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Zhenguang Zhang, Agnes E Coutinho, Tak Yung Man, Tiina M J Kipari, Patrick W F Hadoke, Donald M Salter, Jonathan R Seckl and Karen E Chapman

associated with reduced adipose tissue hypoxia and inflammation ( Michailidou et al . 2012 ) and in cutaneous surgical wounds, where it is associated with improved wound repair ( Small et al . 2005 ). Here, we have generated mice deficient in 11β-HSD1 in

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M A J Hervé, G Meduri, F G Petit, T S Domet, G Lazennec, S Mourah and M Perrot-Applanat

related to the vascular bed type ( Ferrara et al. 2003 ). Factors regulating Flk-1/KDR expression in vivo in endothelial cells are not clearly defined. In tumors, Flk-1/KDR appears to be regulated by hypoxia, an effect probably mediated by VEGF

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Joyce Emons, Andrei S Chagin, Torun Malmlöf, Magnus Lekman, Åsa Tivesten, Claes Ohlsson, Jan M Wit, Marcel Karperien and Lars Sävendahl

-induced recruitment of both estrogen receptor alpha and hypoxia-inducible factor 1 to the vascular endothelial growth factor promoter . Molecular Endocrinology 19 2006 – 2019 . Kember NF Cell kinetics and the control of bone growth Acta Paediatrica 82 Suppl

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P Nguyen, S Khurana, H Peltsch, J Grandbois, J Eibl, J Crispo, D Ansell and T C Tai

programming. This is mediated in part by adaptation of the fetus to adverse conditions that are encountered during development in utero . Examples of such stressors include maternal nutrient restriction, hypoxia, physical trauma, as well as exposure to