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S Hesketh, D S Jessop, S Hogg and M S Harbuz

. Young E & Vazquez D 1996 Hypercortisolemia, hippocampal glucocorticoid receptors and fast feedback. Molecular Psychiatry 1 149 –159. Young W III, Mezey E & Siegel R 1986a Vasopressin and oxytocin mRNAs in

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David A Bechtold and Simon M Luckman

the increasing number of peptides, several G-protein-coupled receptors (GPRs) are now recognised as receptors for the mammalian RFamides. NPFF family Neuropeptide FF (NPFF, shortened from F8Famide) and neuropeptide AF (NPAF

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Roman A Romanov, Alán Alpár, Tomas Hökfelt and Tibor Harkany

steroidogenesis in, and corticosteroid release from, the adrenal cortex ( Munck et al . 1984 , McEwen & Stellar 1993 ). Corticosteroid action is then executed through glucocorticoid receptors ( Gustafsson et al . 1987 ), encoded by the Nr3c1 gene ( McEwen

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A F Roy, Y Benomar, V Bailleux, C M Vacher, A Aubourg, A Gertler, J Djiane and M Taouis

hormones that show significant plasma level changes during these periods. During pregnancy and lactation, other hormones may also contribute to hyperphagia. The lack of central oxytocin action may partly contribute to maternal hyperphagia ( Douglas et al

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Natasha Singh, Bronwen Herbert, Gavin R Sooranna, Nicolas M Orsi, Lydia Edey, Tathagata Dasgupta, Suren R Sooranna, Steven M Yellon and Mark R Johnson

agonists and, in the case of oxytocin, antagonists, are commonly used to promote and inhibit contractions, respectively. However, the use of tocolytics, including the oxytocin receptor antagonist, Atosiban, does not improve neonatal outcomes ( Haram et al

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Kok-Min Seow, Jyun-Lin Lee, Ming-Luen Doong, Seng-Wong Huang, Jiann-Loung Hwang, Wei-Ju Huang, Full-Young Chang, Low-Tone Ho and Chi-Chang Juan

receptor in the inhibition of gastrointestinal motility by oxytocin in ovariectomized rats . European Journal of Pharmacology 580 407 – 415 . ( doi:10.1016/j.ejphar.2007.11.024 ) *(K-M Seow and J-L Lee contributed equally to this work)

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Y Takei, H Hashimoto, K Inoue, T Osaki, K Yoshizawa-Kumagaye, M Tsunemi, T X Watanabe, M Ogoshi, N Minamino and Y Ueta

activator of hypothalamic oxytocin-secreting neurons than adrenomedullin in rats, and its effects are only partially blocked by antagonists for adrenomedullin and calcitonin gene-related peptide receptors . Peptides 28 1104 – 1112 . Katafuchi T Minamino

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A Glover and S J Assinder

Introduction Phytoestrogens are plant-derived, non-steroidal compounds, able to activate oestrogen receptor-α (ERα) and ERβ ( Kuiper et al. 1997 , 1998 ). Phytoestrogens can be divided into three main classes – isoflavones

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Anne-Marie O'Carroll, Gillian M Howell, Emma M Roberts and Stephen J Lolait

paradigm of endocrine secretion . European Journal of Biochemistry 259 3 – 17 . Lee B Yang C Chen TH al Azawi N Hsu WH 1995 Effect of AVP and oxytocin on insulin release: involvement of V1b receptors . American Journal of Physiology

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Jaroslav Kuneš, Veronika Pražienková, Andrea Popelová, Barbora Mikulášková, Jana Zemenová and Lenka Maletínská

antiobesity drugs. Prolactin-releasing peptide in food intake regulation The anorexigenic neuropeptide prolactin-releasing peptide (PrRP) was initially isolated from the hypothalamus as a ligand for the human orphan G-protein-coupled receptor GPR10