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Juan Kong, Yunzi Chen, Guojun Zhu, Qun Zhao and Yan Chun Li

Introduction White adipose tissue not only serves the purpose of an energy store but also functions as an endocrine organ for the regulation of energy homeostasis. Adipocytes release an array of endocrine signals that are integrated into the

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Elias Rawish, Laura Nickel, Franziska Schuster, Ines Stölting, Alex Frydrychowicz, Kathrin Saar, Norbert Hübner, Alaa Othman, Lars Kuerschner and Walter Raasch

Effects on growth, energy homeostasis, and plasma levels of lipids and adipocytokines Initial body weight did not differ between groups (CON chow 23.3 ± 1.4 g; CON HFD 22.8 ± 1.4 g; TEL HFD 23.2 ± 1.8 g; F = 0.4, P  = 0.68). HFD-fed mice developed

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Charlotte Benoit, Hassina Ould-Hamouda, Delphine Crepin, Arieh Gertler, Laurence Amar and Mohammed Taouis

arcuate nucleus (ARC) that project to the paraventricular nucleus (PVN) to adjust energy homeostasis ( Schwartz et al . 2000 ). In the early postnatal period, leptin plays an independent role from regulating body weight and fat size. In newborn rodents, a

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Frank Peelman, Lennart Zabeau, Kedar Moharana, Savvas N Savvides and Jan Tavernier

Introduction Leptin and the leptin receptor (LR) are essential components in the complex genetic wiring diagram underlying energy homeostasis and body weight. The hormone is now known to participate in a wide range of biological functions including

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Hassina Ould Hamouda, Bernadette Delplanque, Yacir Benomar, Delphine Crépin, Laure Riffault, Pascale LeRuyet, Cécile Bonhomme and Mohammed Taouis

subjects is often caused by an inappropriate consumption of different nutrients, including proteins and micronutrients. Indeed, it has been suggested that the impairment of energy homeostasis control is one cause of malnutrition ( Foster et al . 2010

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Laura Marroqui, Eva Tudurí, Paloma Alonso-Magdalena, Iván Quesada, Ángel Nadal and Reinaldo Sousa dos Santos

that pollutants targeting mitochondria would lead to harmful effects, especially on metabolic homeostasis. In fact, the term metabolism-disrupting chemical (MDC) has been recently proposed to refer to a particular class of EDCs that disturbs energy

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Jennifer H Steel, Roger White and Malcolm G Parker

) and energy homeostasis ( Leonardsson et al. 2004 ). This review will focus on the function of RIP140 in the ovary to regulate ovulation and in adipose tissue to regulate fat accumulation. RIP140 binds to nuclear receptors in a ligand

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E H Leder and J T Silverstein

Introduction Pro-opiomelanocortin (POMC) is an important precursor for several peptide hormones involved in a broad variety of functions, ranging from the stress response to energy homeostasis. POMC is expressed mainly in the

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I Sadaf Farooqi and Stephen O'Rahilly

an important role in the regulation of blood pressure and its coupling to changes in weight. Summary Finally, the discovery of leptin, and the central pathways involved in energy homeostasis that it regulates, has paved the way for the understanding

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M Skrzypski, M Billert, K W Nowak and M Z Strowski

molecules transmitting the signals upon orexin receptors activation ( Kukkonen & Leonard 2014 , Kukkonen 2014 ). Early reports indicated the importance of orexins and their receptors in controlling body weight and energy homeostasis by stimulating food