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Madeleine R Di Natale, Alita Soch, Ilvana Ziko, Simone N De Luca, Sarah J Spencer and Luba Sominsky

Introduction Psychological stress has well-known inhibitory effects on reproductive function ( Rivier & Rivest 1991 , Tilbrook et al. 2002 , Young et al. 2006 , Lynch et al. 2014 ), suppressing hypothalamic–pituitary–gonadal (HPG

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Miroslav Adzic, Jelena Djordjevic, Ana Djordjevic, Ana Niciforovic, Constantinos Demonacos, Marija Radojcic and Marija Krstic-Demonacos

example, JNK pathway was reported to play a significant role in various brain regions as signalling mediator of different types of physical and psychological stressors ( Meller et al . 2003 , Shen et al . 2004 ). The capability of JNKs to phosphorylate

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Alberto Loizzo, Santi M Spampinato, Gabriele Campana, Stefano Vella, Andrea Fortuna, Loredana Costa, Anna Capasso, Palmiero Monteleone, Paolo Renzi and Stefano Loizzo

hypothesis that a double stress paradigm (mild psychological stress plus mild pain stress) daily applied to nursing male mice produces enduring body metabolic alterations similar to mild type 2 diabetes. Here, we show also two new series of findings: 1

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Georgia Balsevich, Andres Uribe, Klaus V Wagner, Jakob Hartmann, Sara Santarelli, Christiana Labermaier and Mathias V Schmidt

Introduction The global prevalence of obesity is rising ( Yach et al . 2006 ), emphasizing the need to decipher the complex regulatory mechanisms underlying energy balance. Evidence indicates that chronic stress is a risk factor for obesity

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S Babic, M Pokusa, V Danevova, S T Ding and D Jezova

during stress conditions is limited. The activation of release of anterior pituitary hormones, such as adrenocorticotropic hormone (ACTH) or prolactin, is one of the main characteristics of the stress response ( Jezova & Hlavacova 2008 ). Knowledge

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Francesca Spiga, Louise R Harrison, Cliona P MacSweeney, Fiona J Thomson, Mark Craighead and Stafford L Lightman

of the vasopressin 1b receptor (AVPR1B; Aguilera et al . 1994 ). AVP levels and secretion, as well as AVP mRNA expression within the parvocellular PVN, increase in response to repeated exposure to stressors such as restraint ( de Goeij et al

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Gabriele E Mattos, Jan-Michael Heinzmann, Stefanie Norkowski, Jean-Christophe Helbling, Amandine M Minni, Marie-Pierre Moisan and Chadi Touma

subjected to a psychological stressor in the SR test (SRT). The SRT consists of a 15-min restraint period and two tail blood samples immediately before ( t =0) and after restraint ( t =15) ( Touma et al . 2008 ). After the SRT, animals were transferred back

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Sara Sandrini, Marwh Aldriwesh, Mashael Alruways and Primrose Freestone

-responsive bacteria. Stress and health Stress is generally described as experiences that are psychologically or physiologically challenging. In animals, stress results in a bi-directional communication between the brain and the peripheral organs and is

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Chad Osterlund and Robert L Spencer

negative feedback function associated with a wide range of clinical disorders (e.g. depression, post-traumatic stress disorder, type II diabetes, chronic fatigue syndrome, fibromyalgia, and chronic facial pain) and associated precursor conditions (e

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Francesca Spiga, Louise R Harrison, Susan Wood, David M Knight, Cliona P MacSweeney, Fiona Thomson, Mark Craighead and Stafford L Lightman

attenuated depression-like behaviour in forced swimming and sucrose preference tests ( Mlynarik et al . 2007 ). Although V 1b R knockout (KO) mice exhibit a normal corticosterone response to the acute psychological stress of restraint ( Lolait et al . 2007