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Wang Xiao, Fei Beibei, Shen Guangsi, Jiang Yu, Zhang Wen, Huang Xi and Xu Youjia

of these results, changes of other parameters were in accordance with theoretical analysis. In addition, a significant decrease in bone formation and resorption activities were observed in our model, recapitulating iron-induced osteopenia in

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K J Oldknow, V E MacRae and C Farquharson

05557 ) Ljunggren Ö Bolinder J Johansson L Wilding J Langkilde AM Sjöström CD Sugg J Parikh S 2012 Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately

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Jessica L Pierce, Ke-Hong Ding, Jianrui Xu, Anuj K Sharma, Kanglun Yu, Natalia del Mazo Arbona, Zuleika Rodríguez-Santos, Paul J Bernard, Wendy B Bollag, Maribeth H Johnson, Mark W Hamrick, Dana L Begun, Xing-Ming Shi, Carlos M Isales and Meghan E McGee-Lawrence

from the mice to quantify markers of bone formation and resorption. Circulating markers were verified in a site-specific fashion through histomorphometric measurements of metaphyseal trabecular bone in the proximal tibia (TRAP staining) and distal femur

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Chandrika D Mahalingam, Tanuka Datta, Rashmi V Patil, Jaclynn Kreider, R Daniel Bonfil, Keith L Kirkwood, Steven A Goldstein, Abdul B Abou-Samra and Nabanita S Datta

the present time, our results imply that ON levels may play a role in modulating the balance between bone formation and resorption in response to PTH in Mkp1 null mice. Using different osteogenic cells it has been shown that ALKP activity is not

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Guillaume Mabilleau, Marie Pereira and Chantal Chenu

reflect those in human bone tissue. Bone turnover markers and circulating sclerostin levels Multiple studies in humans have found that serum markers of bone formation and resorption are reduced in diabetic individuals vs non-diabetic controls

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David J Mellis, Cecile Itzstein, Miep H Helfrich and Julie C Crockett

-8674(00)80209-3 . Sims NA Gooi JH 2008 Bone remodeling: multiple cellular interactions required for coupling of bone formation and resorption . Seminars in Cell and Developmental Biology 19 444 – 451 . doi:10.1016/j.semcdb.2008.07.016 . Smink JJ Begay V

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K Boelaert and J A Franklyn

direct effects upon bone formation and resorption, thyroid hormone excess resulting in net loss of bone and hence reduction in bone mineral density (BMD) ( Ross 1994 ). It is well recognised that overt hyperthyroidism results in reduction in BMD and that

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Katherine A Staines, Vicky E MacRae and Colin Farquharson

, Raynal et al . 1996 , Malaval et al . 2008 , Valverde et al . 2008 ). This has been further examined in BSP transgenic mice in which an uncoupling of bone formation and resorption resulted in an osteopenia-like phenotype ( Valverde et al . 2008

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S F Ahmed and C Farquharson

trabeculae in socs2 null mice appeared to be more ‘plate-like’ and more connected, which is consistent with greater ‘strength’. Osteocalcin and TRAP5b, respective markers of bone formation and resorption, were also reported to be higher in the socs2 null

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Victoria E DeMambro, Masanobu Kawai, Thomas L Clemens, Keertik Fulzele, Jane A Maynard, Caralina Marín de Evsikova, Kenneth R Johnson, Ernesto Canalis, Wesley G Beamer, Clifford J Rosen and Leah Rae Donahue

Mishra S Rosen CJ Beamer WG Turner RT Powell DR Murphy LJ 2003 Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice . Journal of Bone and Mineral Research 18 1834 – 1841