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Xiaoqin Shi, Xinyu Li, Yi Hou, Xuemei Cao, Yuyao Zhang, Heng Wang, Hongyin Wang, Chuan Peng, Jibin Li, Qifu Li, Chaodong Wu, and Xiaoqiu Xiao

following primary antibodies: p-STAT3 (1:1000, 9145, Tyr705) and STAT3 (1:1000, 9139) (Cell Signaling Technology), and suppressor of cytokine signaling 3 (SOCS3) (1:1000, ab16030), and then the secondary antibodies for 1 h at room temperature. The protein

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C Viguié, Y Chilliard, V Gayrard, N Picard-Hagen, P Monget, A Dutour, and P-L Toutain

. 2001 b ). Non-metabolic beneficial effects might arise from increased GH secretion. Indeed, GH exhibits IGF-I-independent neuroprotective effects ( Scheepens et al. 2001 ) and can induce the expression of suppressors of cytokine signalling

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Anshu Gupta, Malathi Srinivasan, Supaporn Thamadilok, and Mulchand S Patel

; Upstate Cell Signaling, Chicago, IL, USA), signal transducers and activators of transcription-3 (STAT-3; Cell Signaling Solutions, Lake Placid, NY, USA) and suppressors of cytokine signaling-3 (SOCS-3; Affinity BioReagents, Golden, CO, USA). Statistical

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Ke Cui, Giamal N Luheshi, and Patricia Boksa

hypothalamic suppressor of cytokine signaling 3 ( Socs3 ) mRNA, an indicator of IL-6 signaling pathway activation. Non-pregnant female and E15 pregnant rats ( n =7–8/experimental group) were injected i.p. with metyrapone (75 mg/kg) or its vehicle (40% propylene

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David J Flint, Nadine Binart, Stephanie Boumard, John J Kopchick, and Paul Kelly

showed it to be upregulated in lactation. They proceeded to show that PRL could induce suppressor of cytokine signaling proteins in adipocytes cultured in vitro , or in adipose tissue of PRL-transgenic mice, providing evidence for induction of

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Marion Walser, Maria Teresa Samà, Ruth Wickelgren, Maria Åberg, Mohammad Bohlooly-Y, Bob Olsson, Jan Törnell, Jörgen Isgaard, and N David Åberg

numbers ( Ransome et al . 2004 ), while increasing GH signalling via disrupting the suppressor of cytokine signalling 2 (SOCS2) decreased neuron numbers and presumably increased astrocyte numbers ( Turnley et al . 2002 ). Neither from these studies nor

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Richard R Almon, Debra C DuBois, Jin Y Jin, and William J Jusko

. Martinez-Riquelme AE & Allison SP 2003 Insulin revisited. Clinical Nutrition 22 7 –15. Mooney RA , Senn J, Cameron S, Inamdar N, Boivin LM, Shang Y & Furlanetto RW 2001 Suppressors of cytokine signaling-1 and -6

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V E MacRae, C Farquharson, and S F Ahmed

, cytokines may induce a state of IGF-I resistance by reducing IGF-I signal transduction in chondrocytes by inhibiting insulin receptor substrate-1 phosphorylation ( Broussard et al. 2004 ) by the up-regulation of the suppressor of cytokine-signalling

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Mauricio da Silva Krause, Aline Bittencourt, Paulo Ivo Homem de Bittencourt Jr, Neville H McClenaghan, Peter R Flatt, Colin Murphy, and Philip Newsholme

Mooney RA 2003 Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes . Journal of Biological Chemistry 278 13740 – 13746 . doi:10.1074/jbc.M210689200 . Smukler SR Tang

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L Lundholm, G Bryzgalova, H Gao, N Portwood, S Fält, K D Berndt, A Dicker, D Galuska, J R Zierath, J-Å Gustafsson, S Efendic, K Dahlman-Wright, and A Khan

, member 1 Suppressor of cytokine signaling 2 Syndecan 4 Decreased by PPT and E 2 Butyrylcholinesterase Esterase 22 Fatty acid desaturase 2 Glucose-6-phosphatase, catalytic Glutamate-cysteine ligase, catalytic subunit Glutathione S-transferase, α 2 (Yc2